GYY4137, a H2S donor, ameliorates kidney injuries in diabetic mice by modifying renal ROS-associated enzymes.

[1]  O. Pol,et al.  The Beneficial Effects of Heme Oxygenase 1 and Hydrogen Sulfide Activation in the Management of Neuropathic Pain, Anxiety- and Depressive-like Effects of Paclitaxel in Mice , 2022, Antioxidants.

[2]  A. Papapetropoulos,et al.  Hydrogen Sulfide and the Kidney: Physiological Roles, Contribution to Pathophysiology, and Therapeutic Potential. , 2021, Antioxidants & redox signaling.

[3]  N. Samsu.  Diabetic Nephropathy: Challenges in Pathogenesis, Diagnosis, and Treatment , 2021, BioMed research international.

[4]  Xiaoyan Wang,et al.  Glucose‐induced decrease of cystathionine β‐synthase mediates renal injuries , 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[5]  Asadullah Madni,et al.  Role of Oxidative Stress and Reduced Endogenous Hydrogen Sulfide in Diabetic Nephropathy , 2021, Drug design, development and therapy.

[6]  A. Bavec,et al.  The Structure and Function of Paraoxonase-1 and Its Comparison to Paraoxonase-2 and -3 , 2020, Molecules.

[7]  R. Ekart,et al.  Oxidative Stress Markers in Chronic Kidney Disease with Emphasis on Diabetic Nephropathy , 2020, Antioxidants.

[8]  J. Chen,et al.  Study on the inhibitive effect of Catalpol on diabetic nephropathy. , 2020, Life sciences.

[9]  M. Cooper,et al.  Targeting oxidative stress and anti-oxidant defence in diabetic kidney disease , 2020, Journal of Nephrology.

[10]  R. Kitazawa,et al.  New Insights into the Pathogenesis of Diabetic Nephropathy: Proximal Renal Tubules Are Primary Target of Oxidative Stress in Diabetic Kidney , 2020, Acta histochemica et cytochemica.

[11]  P. Moore,et al.  Biological effects of GYY4137 and other phosphorothioate-based hydrogen sulfide donors. , 2019, Antioxidants & redox signaling.

[12]  G. Farrugia,et al.  Heme Oxygenase-2 Protects Against Ischemic Acute Kidney Injury: The Influence of Age and Sex. , 2019, American journal of physiology. Renal physiology.

[13]  H. Omar,et al.  Hydrogen sulfide modulates SIRT1 and suppresses oxidative stress in diabetic nephropathy , 2019, Molecular and Cellular Biochemistry.

[14]  Shangha Pan,et al.  GYY4137 attenuates LPS-induced acute lung injury via heme oxygenase-1 modulation. , 2019, Pulmonary pharmacology & therapeutics.

[15]  F. Flores-Murrieta,et al.  Possible involvement of peripheral TRP channels in the hydrogen sulfide-induced hyperalgesia in diabetic rats , 2019, BMC Neuroscience.

[16]  A. Van Schepdael,et al.  Oxidative stress in chronic kidney disease , 2018, Pediatric Nephrology.

[17]  Yu Lin,et al.  Specific downregulation of cystathionine β‐synthase expression in the kidney during obesity , 2018, Physiological reports.

[18]  D. Grandy,et al.  Antihypertensive effect of etamicastat in dopamine D2 receptor-deficient mice , 2018, Hypertension Research.

[19]  K. Tuttle,et al.  Diabetic Kidney Disease: Challenges, Progress, and Possibilities. , 2017, Clinical journal of the American Society of Nephrology : CJASN.

[20]  A. Bitto,et al.  Oxidative Stress: Harms and Benefits for Human Health , 2017, Oxidative medicine and cellular longevity.

[21]  V. A. Villar,et al.  Increased renal oxidative stress in salt‐sensitive human GRK4&ggr;486V transgenic mice , 2017, Free radical biology & medicine.

[22]  George J. Dugbartey,et al.  Diabetic nephropathy: A potential savior with ‘rotten-egg’ smell , 2017, Pharmacological reports : PR.

[23]  H. Abboud,et al.  Hydrogen sulfide inhibits high glucose-induced NADPH oxidase 4 expression and matrix increase by recruiting inducible nitric oxide synthase in kidney proximal tubular epithelial cells , 2017, Journal of Biological Chemistry.

[24]  D. Féliers,et al.  Hydrogen Sulfide in Renal Physiology and Disease. , 2016, Antioxidants & redox signaling.

[25]  M. Cooper,et al.  Diabetes and Kidney Disease: Role of Oxidative Stress. , 2016, Antioxidants & redox signaling.

[26]  M. Hezel,et al.  Dietary nitrate improves age-related hypertension and metabolic abnormalities in rats via modulation of angiotensin II receptor signaling and inhibition of superoxide generation. , 2016, Free radical biology & medicine.

[27]  R. Ge,et al.  Novel hydrogen sulfide-releasing compound, S-propargyl-cysteine, prevents STZ-induced diabetic nephropathy. , 2016, Biochemical and biophysical research communications.

[28]  Q. Gao,et al.  [Protective effect of hydrogen sulfide on kidneys of type 1 diabetic rats]. , 2016, Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology.

[29]  H. van Goor,et al.  Hydrogen sulfide in renal physiology, disease and transplantation--the smell of renal protection. , 2015, Nitric oxide : biology and chemistry.

[30]  Xiaoping Zhou,et al.  Hydrogen Sulfide Alleviates Diabetic Nephropathy in a Streptozotocin-induced Diabetic Rat Model , 2014, The Journal of Biological Chemistry.

[31]  L. Guarente,et al.  Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes , 2013, Nature Medicine.

[32]  A. Mima.  Inflammation and Oxidative Stress in Diabetic Nephropathy: New Insights on Its Inhibition as New Therapeutic Targets , 2013, Journal of diabetes research.

[33]  A. Sparatore,et al.  Role of Paraoxonase-1 in the Protection of Hydrogen Sulfide-Donating Sildenafil (ACS6) Against Homocysteine-Induced Neurotoxicity , 2013, Journal of Molecular Neuroscience.

[34]  Q. Ma.  Role of nrf2 in oxidative stress and toxicity. , 2013, Annual review of pharmacology and toxicology.

[35]  A. Elmarakby,et al.  Relationship between oxidative stress and inflammatory cytokines in diabetic nephropathy. , 2012, Cardiovascular therapeutics.

[36]  Yu Huang,et al.  Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide. , 2011, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[37]  K. Barišić,et al.  The paraoxonase 1, 2 and 3 in humans. , 2011, Biochemia medica.

[38]  P. Winocour,et al.  Oxidative stress in early diabetic nephropathy: fueling the fire , 2011, Nature Reviews Endocrinology.

[39]  A. Sparatore,et al.  Activity of a new hydrogen sulfide-releasing aspirin (ACS14) on pathological cardiovascular alterations induced by glutathione depletion in rats. , 2010, European journal of pharmacology.

[40]  U. Förstermann,et al.  One Enzyme, Two Functions , 2010, The Journal of Biological Chemistry.

[41]  M. Schwartzman,et al.  Heme Oxygenase-2 Deletion Causes Endothelial Cell Activation Marked by Oxidative Stress, Inflammation, and Angiogenesis , 2009, Journal of Pharmacology and Experimental Therapeutics.

[42]  V. A. Villar,et al.  Lipid Rafts Keep NADPH Oxidase in the Inactive State in Human Renal Proximal Tubule Cells , 2008, Hypertension.

[43]  U. Förstermann,et al.  Paraoxonase-2 Reduces Oxidative Stress in Vascular Cells and Decreases Endoplasmic Reticulum Stress–Induced Caspase Activation , 2007, Circulation.

[44]  L. Rodella,et al.  Heme oxygenase-2 deficiency contributes to diabetes-mediated increase in superoxide anion and renal dysfunction. , 2006, Journal of the American Society of Nephrology : JASN.

[45]  S. Doré,et al.  Catalytically inactive heme oxygenase-2 mutant is cytoprotective. , 2005, Free radical biology & medicine.

[46]  G. Catignani,et al.  Antioxidants and Prevention of Chronic Disease , 2004, Critical reviews in food science and nutrition.

[47]  G. Franceschini,et al.  Enzymatically Active Paraoxonase-1 Is Located at the External Membrane of Producing Cells and Released by a High Affinity, Saturable, Desorption Mechanism* , 2002, The Journal of Biological Chemistry.

[48]  Y. Goto,et al.  Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria. , 2010, Antioxidants & redox signaling.