Track 1 – Track 5

[1]  C. Townsend,et al.  Fatty acid synthase inhibition activates AMP-activated protein kinase in SKOV3 human ovarian cancer cells. , 2007, Cancer research.

[2]  R. Shaw,et al.  Glucose metabolism and cancer. , 2006, Current opinion in cell biology.

[3]  F. Kuhajda,et al.  Fatty acid synthase and cancer: new application of an old pathway. , 2006, Cancer research.

[4]  Shailendra Giri,et al.  5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside Inhibits Cancer Cell Proliferation in Vitro and in Vivo via AMP-activated Protein Kinase* , 2005, Journal of Biological Chemistry.

[5]  D. Kwiatkowski,et al.  Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways. , 2005, Human molecular genetics.

[6]  C. Thompson,et al.  ATP citrate lyase is an important component of cell growth and transformation , 2005, Oncogene.

[7]  A. Noël,et al.  Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype. , 2005, Cancer research.

[8]  Moira A. Taylor,et al.  Deleterious effects of omitting breakfast on insulin sensitivity and fasting lipid profiles in healthy lean women. , 2005, The American journal of clinical nutrition.

[9]  C. Thompson,et al.  Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. , 2004, Molecular cell.

[10]  N. Sonenberg,et al.  Upstream and downstream of mTOR. , 2004, Genes & development.

[11]  N. Ruderman,et al.  AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms. , 2004, Biochemical and biophysical research communications.

[12]  Bruce J. Aronow,et al.  Chromatin Immunoprecipitation Assays Footprints in Glycolytic Genes by Evaluation of Myc E-box Phylogenetic Supplemental Material , 2004 .

[13]  A. Alavi,et al.  Akt Stimulates Aerobic Glycolysis in Cancer Cells , 2004, Cancer Research.

[14]  T. Nishizaki,et al.  Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase. , 2004, Biochemical pharmacology.

[15]  Lewis C Cantley,et al.  The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[16]  K. Inoki,et al.  TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival , 2003, Cell.

[17]  David Carling,et al.  Supplemental Data LKB 1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade , 2003 .

[18]  B. Kemp Faculty Opinions recommendation of Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. , 2003 .

[19]  Jérôme Boudeau,et al.  Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade , 2003, Journal of biology.

[20]  R. Houlston,et al.  Further observations on LKB1/STK11 status and cancer risk in Peutz–Jeghers syndrome , 2003, British Journal of Cancer.

[21]  T. Lawrence,et al.  AMPK-beta1 subunit is a p53-independent stress responsive protein that inhibits tumor cell growth upon forced expression. , 2003, Carcinogenesis.

[22]  M. Rider,et al.  Sustained activation of AMP‐activated protein kinase induces c‐Jun N‐terminal kinase activation and apoptosis in liver cells , 2002, FEBS letters.

[23]  D. Hardie,et al.  AMP‐activated protein kinase: the energy charge hypothesis revisited , 2001, BioEssays : news and reviews in molecular, cellular and developmental biology.

[24]  D J Campbell,et al.  AMP-activated protein kinase, super metabolic regulator. , 2001, Biochemical Society transactions.

[25]  S. Goodman,et al.  Very high risk of cancer in familial Peutz-Jeghers syndrome. , 2000, Gastroenterology.

[26]  D. Carling,et al.  Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia , 2000, Current Biology.

[27]  D. Kwiatkowski,et al.  Molecular genetic advances in tuberous sclerosis , 2000, Human Genetics.

[28]  M. Cascante,et al.  Transforming growth factor beta2 promotes glucose carbon incorporation into nucleic acid ribose through the nonoxidative pentose cycle in lung epithelial carcinoma cells. , 2000, Cancer research.

[29]  C. Townsend,et al.  Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts. , 2000, Cancer research.

[30]  D. Hardie,et al.  AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge. , 1999, The Biochemical journal.

[31]  R. Coleman,et al.  AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target. , 1999, The Biochemical journal.

[32]  D J Schaid,et al.  Increased Risk for Cancer in Patients with the Peutz-Jeghers Syndrome , 1998, Annals of Internal Medicine.

[33]  M. Stratton,et al.  A serine/threonine kinase gene defective in Peutz–Jeghers syndrome , 1998, Nature.

[34]  B. Kemp,et al.  Posttranslational Modifications of the 5′-AMP-activated Protein Kinase β1 Subunit* , 1997, The Journal of Biological Chemistry.

[35]  A. Engel,et al.  Cortical Tuber Count: A Biomarker Indicating Neurologic Severity of Tuberous Sclerosis Complex , 1997, Journal of child neurology.

[36]  S. Hawley,et al.  Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase* , 1996, The Journal of Biological Chemistry.

[37]  D. Hardie,et al.  5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells? , 1995, European journal of biochemistry.

[38]  L. Jacobs,et al.  Fatty acid synthesis: a potential selective target for antineoplastic therapy. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[39]  V. McKusick,et al.  Generalized intestinal polyposis and melanin spots of the oral mucosa, lips and digits; a syndrome of diagnostic significance. , 1949, The New England journal of medicine.

[40]  David Carling,et al.  The AMP-activated protein kinase cascade--a unifying system for energy control. , 2004, Trends in biochemical sciences.

[41]  M. Carlson,et al.  The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? , 1998, Annual review of biochemistry.

[42]  J. Nezu,et al.  Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase. , 1998, Nature genetics.

[43]  H. Kolb,et al.  Fatty-acid biosynthesis in man, a pathway of minor importance. Purification, optimal assay conditions, and organ distribution of fatty-acid synthase. , 1986, Biological chemistry Hoppe-Seyler.

[44]  D. Hardie Printed in U.S.A. Copyright © 2003 by The Endocrine Society doi: 10.1210/en.2003-0982 Minireview: The AMP-Activated Protein Kinase Cascade: The Key Sensor of Cellular Energy Status , 2022 .