论文信息 - Reversal of isolated hypogonadotropic hypogonadism: long‐term integrity of hypothalamo–pituitary–testicular axis in two men is dependent on intermittent androgen exposure

Reversal of isolated hypogonadotropic hypogonadism: long‐term integrity of hypothalamo–pituitary–testicular axis in two men is dependent on intermittent androgen exposure

Fawzi Bakiri*, Javier Herrera†, Maria Riestra‡, Olivier Perrichot*, Joaquin Pertierra§, Oscar Domingo Bruno†, Thierry Brue¶** and Frederic Castinetti¶** *Department of Endocrinology, Centre Hospitalier Departemental Felix Guyon, St Denis, France, †Division of Endocrinology, Hospital de Cl ınicas, University of Buenos Aires, Buenos Aires, Argentina, ‡Endocrinology Unit, Hospital de Cabue~ nes, Gij on, §Hospital Universitario Central de Asturias, Oviedo, Spain, ¶Department of Endocrinology, Aix-Marseille University, Reference Center for Rare Pituitary Diseases, La Timone Hospital, Assistance Publique Hôpitaux de Marseille, **Centre de Recherches en Neurobiologie et Neurophysiologie de Marseille (CRN2M), CNRS UMR7286, Marseille, France E-mail: frederic.castinetti@ap-hm.fr

R. Quinton | A. Santhakumar | Ravikumar Balasubramanian | Margaret Miller

[1] N. Jørgensen,et al. A homozygous R262Q mutation in the gonadotropin‐releasing hormone receptor presenting as reversal of hypogonadotropic hypogonadism and late‐onset hypogonadism , 2013, Clinical endocrinology.

[2] J. Stockman. A Genetic Basis for Functional Hypothalamic Amenorrhea , 2012 .

[3] R. Quinton,et al. A genetic basis for functional hypothalamic amenorrhea. , 2011, The New England journal of medicine.

[4] W. Crowley,et al. The long-term clinical follow-up and natural history of men with adult-onset idiopathic hypogonadotropic hypogonadism. , 2010, The Journal of clinical endocrinology and metabolism.

[5] E. Laws. Pituitary Tumor Apoplexy: A Review , 2008, Journal of intensive care medicine.

[6] A. Latronico,et al. Update on the etiology, diagnosis and therapeutic management of sexual precocity. , 2008, Arquivos brasileiros de endocrinologia e metabologia.

[7] R. Quinton,et al. Reversal of idiopathic hypogonadotropic hypogonadism. , 2007, The New England journal of medicine.

[8] R. Quinton,et al. Kallmann's syndrome: is it always for life? , 1999, Clinical endocrinology.

[9] Adult‐onset idiopathic hypogonadotropic hypogonadism — A treatable form of male infertility , 1997 .

[10] W. Crowley,et al. Adult-onset idiopathic hypogonadotropic hypogonadism--a treatable form of male infertility. , 1997, The New England journal of medicine.