Performance of three preoperative risk indices; CABDEAL, EuroSCORE and Cleveland models in a prospective coronary bypass database.

OBJECTIVES The aim of the present study was to evaluate the performance of three different preoperative risk models in the prediction of postoperative morbidity and mortality in coronary artery bypass (CAB) surgery. METHODS Data on 1132 consecutive CAB patients were prospectively collected, including preoperative risk factors and postoperative morbidity and in-hospital mortality. The preoperative risk models CABDEAL, EuroSCORE and Cleveland model were used to predict morbidity and mortality. A C statistic (receiver operating characteristic (ROC) curve) was used to test the discrimination of these models. RESULTS The area under the ROC curve for morbidity was 0.772 for the CABDEAL, 0.694 for the EuroSCORE and 0.686 for the Cleveland model. Major morbidity due to postoperative complications occurred in 268 patients (23.6%). The mortality rate was 3.4% (n=38 patients). The ROC curve areas for prediction of mortality were 0.711 for the CABDEAL, 0.826 for the EuroSCORE and 0.858 for the Cleveland model. CONCLUSIONS The CABDEAL model was initially developed for the prediction of major morbidity. Thus, it is not surprising that this model evinced the highest predictive value for increased morbidity in this database. Both the Cleveland and the EuroSCORE models were better predictive of mortality. These results have implications for the selection of risk indices for different purposes. The simple additive CABDEAL model can be used as a hand-held model for preoperative estimation of patients' risk of postoperative morbidity, while the EuroSCORE and Cleveland models are to be preferred for the prediction of mortality in a large patient sample.

[1]  T. Kurki,et al.  Preoperative prediction of postoperative morbidity in coronary artery bypass grafting. , 1996, The Annals of thoracic surgery.

[2]  J. Tu,et al.  Multicenter validation of a risk index for mortality, intensive care unit stay, and overall hospital length of stay after cardiac surgery. Steering Committee of the Provincial Adult Cardiac Care Network of Ontario. , 1995, Circulation.

[3]  P. Schulman Bayes' theorem--a review. , 1984, Cardiology clinics.

[4]  E L Hannan,et al.  Improving the outcomes of coronary artery bypass surgery in New York State. , 1994, JAMA.

[5]  S. Lemeshow,et al.  European system for cardiac operative risk evaluation (EuroSCORE). , 1999, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[6]  A. Bernstein,et al.  A method of uniform stratification of risk for evaluating the results of surgery in acquired adult heart disease. , 1989, Circulation.

[7]  S. Ferraris,et al.  Risk factors for postoperative morbidity. , 1996, Journal of Thoracic and Cardiovascular Surgery.

[8]  J. Hanley,et al.  The meaning and use of the area under a receiver operating characteristic (ROC) curve. , 1982, Radiology.

[9]  G. Beck,et al.  Stratification of morbidity and mortality outcome by preoperative risk factors in coronary artery bypass patients. A clinical severity score. , 1992, JAMA.

[10]  F H Edwards,et al.  Use of a Bayesian statistical model for risk assessment in coronary artery surgery. , 1988, The Annals of thoracic surgery.

[11]  V. Parsonnet Risk Stratification in Cardiac Surgery: Is it Worthwhile? , 1995, Journal of cardiac surgery.

[12]  M. Hippeläinen,et al.  Intra-institutional prediction of outcome after cardiac surgery: comparison between a locally derived model and the EuroSCORE. , 2000, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[13]  J. Alpert,et al.  ACC/AHA guidelines for coronary artery bypass graft surgery , 1999 .

[14]  M. Südkamp,et al.  Risk stratification in heart surgery: comparison of six score systems. , 2000, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[15]  K. Skarvan,et al.  Prospective evaluation of 3 risk stratification scores in cardiac surgery. , 2000, The Thoracic and cardiovascular surgeon.

[16]  T. Higgins Quantifying risk and assessing outcome in cardiac surgery. , 1998, Journal of cardiothoracic and vascular anesthesia.