IN VITRO ANTIFUNGAL ACTIVITY OF LEAF AND STEM BARK EXTRACTS OF THE ENDANGERED TRADITIONAL MEDICINAL TREE SPECIES, HILDEGARDIA POPULIFOLIA (ROXB.) SCHOTT & ENDL.

Objective: The present study describes the antifungal activity of various alcoholic extracts of leaf and stem bark parts of Hildegardia populifolia (Sterculiaceae) and to determine minimum inhibitory concentration against certain fungal pathogens. Methods: Various extracts of leaf and stem bark were assessed for antifungal activity against the species, Aspergillus fumigatus, A. niger, Candida albicans, Paecilomyces lilacinus, Trichoderma viride, Mucor sp., Fusarium sp. and Penicillium sp. by disc diffusion method. The minimum inhibitory concentration (MIC) was also determined. Ampilcillin was used as standard. Results: Methanolic extract had highest antifungal activity against the tested fungi than the other solvent extracts. Further, by using most susceptible fungi, the MIC determined was 400µg/mL. Conclusion: These results support that the leaf and stem bark of H. populifolia have prominent antifungal activity and it can be used to cure mycotic infections.

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