Oral supplementation with whey proteins increases plasma glutathione levels of HIV‐infected patients

HIV infection is characterized by an enhanced oxidant burden and a systemic deficiency of the tripeptide glutathione (GSH), a major antioxidant. The semi‐essential amino acid cysteine is the main source of the free sulfhydryl group of GSH and limits its synthesis. Therefore, different strategies to supplement cysteine supply have been suggested to increase glutathione levels in HIV‐infected individuals. The aim of this study was to evaluate the effect of oral supplementation with two different cysteine‐rich whey protein formulas on plasma GSH levels and parameters of oxidative stress and immune status in HIV‐infected patients.

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