Screening of Candidate Coronary Artery Disease Genes in Pakistani Population

[1]  P. Armitage Tests for Linear Trends in Proportions and Frequencies , 1955 .

[2]  V. Froelicher,et al.  Analysis of epidemiologic studies of physical inactivity as risk factor for coronary artery disease , 1973 .

[3]  A. Copley,et al.  The physiological significance of the endoendothelial fibrin lining (EEFL) as the critical interface in the "vessel-blood organ' and the importance of in vivo "fibrinogenin formation' in health and disease. , 1983, Thrombosis research.

[4]  J. Walker,et al.  The delta-subunit of ATP synthase from bovine heart mitochondria. Complementary DNA sequence of its import precursor cloned with the aid of the polymerase chain reaction. , 1990, The Biochemical journal.

[5]  G. Jansen,et al.  Who Are Guidelines For , 1990 .

[6]  D. Levy,et al.  Lipids and risk of coronary heart disease. The Framingham Study. , 1992, Annals of epidemiology.

[7]  G. Watts,et al.  Effects on coronary artery disease of lipid-lowering diet, or diet plus cholestyramine, in the St Thomas' Atherosclerosis Regression Study (STARS) , 1992, The Lancet.

[8]  Scandinavian Simvastatin Survival Study Group Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S) , 1994, The Lancet.

[9]  L. Berkman,et al.  Genetic susceptibility to death from coronary heart disease in a study of twins. , 1994, The New England journal of medicine.

[10]  P. Wilson,et al.  Established risk factors and coronary artery disease: the Framingham Study. , 1994, American journal of hypertension.

[11]  D. Wilcken,et al.  Polymorphisms of the apolipoprotein E gene and severity of coronary artery disease defined by angiography. , 1995, Arteriosclerosis, thrombosis, and vascular biology.

[12]  T. Mazzone Apolipoprotein E secretion by macrophages: its potential physiological functions , 1996, Current opinion in lipidology.

[13]  Jonathan D. Smith,et al.  Apolipoprotein E allele–specific antioxidant activity and effects on cytotoxicity by oxidative insults and β–amyloid peptides , 1996, Nature Genetics.

[14]  K. Marder,et al.  The APOE- (cid:101) 4 Allele and the Risk of Alzheimer Disease Among African Americans, Whites, and Hispanics , 2001 .

[15]  A. Gotto Triglyceride as a risk factor for coronary artery disease. , 1998, The American journal of cardiology.

[16]  S. Yusuf,et al.  Cardiovascular and cancer mortality among Canadians of European, south Asian and Chinese origin from 1979 to 1993: an analysis of 1.2 million deaths. , 1999, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[17]  A. Vaughan,et al.  The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway. , 1999, The Journal of clinical investigation.

[18]  M. Daly,et al.  Two loci on chromosomes 2 and X for premature coronary heart disease identified in early- and late-settlement populations of Finland. , 2000, American journal of human genetics.

[19]  J. Pritchard,et al.  Linkage disequilibrium in humans: models and data. , 2001, American journal of human genetics.

[20]  S. Yusuf,et al.  Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization. , 2001, Circulation.

[21]  A. Sharrett,et al.  Coronary Heart Disease Prediction From Lipoprotein Cholesterol Levels, Triglycerides, Lipoprotein(a), Apolipoproteins A-I and B, and HDL Density Subfractions: The Atherosclerosis Risk in Communities (ARIC) Study , 2001, Circulation.

[22]  C. Dina,et al.  A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27. , 2001, Human molecular genetics.

[23]  Y. Zhi Apolipoprotein E Alleles, Dyslipidemia,and Coronary Heart Disease , 2001 .

[24]  Pardis C Sabeti,et al.  Linkage disequilibrium in the human genome , 2001, Nature.

[25]  A. Tonkin,et al.  Genome-Wide Linkage Analysis of the Acute Coronary Syndrome Suggests a Locus on Chromosome 2 , 2002, Arteriosclerosis, thrombosis, and vascular biology.

[26]  T. Henry,et al.  Pharmacological Treatment of Coronary Artery Disease With Recombinant Fibroblast Growth Factor-2: Double-Blind, Randomized, Controlled Clinical Trial , 2002, Circulation.

[27]  R. Collins,et al.  Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies , 2002, The Lancet.

[28]  B. Sobel Effects of glycemic control and other determinants on vascular disease in type 2 diabetes. , 2002, The American journal of medicine.

[29]  S. Liu-Cordero Patterns of linkage disequilibrium in the human genome , 2002 .

[30]  A. Simon,et al.  Intima–media thickness: a new tool for diagnosis and treatment of cardiovascular risk , 2002, Journal of hypertension.

[31]  Lisa J. Martin,et al.  A comprehensive linkage analysis for myocardial infarction and its related risk factors , 2002, Nature Genetics.

[32]  W. Dietz,et al.  Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. , 2002, JAMA.

[33]  A. Yashin,et al.  Heritability of death from coronary heart disease: a 36‐year follow‐up of 20 966 Swedish twins , 2002, Journal of internal medicine.

[34]  Berrit C Stroehla,et al.  Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review. , 2002, American journal of epidemiology.

[35]  A. Lakkaraju,et al.  Low-density Lipoprotein Receptor-related Protein Mediates the Endocytosis of Anionic Liposomes in Neurons* 210 , 2002, The Journal of Biological Chemistry.

[36]  H. Izawa,et al.  Prediction of the risk of myocardial infarction from polymorphisms in candidate genes. , 2002 .

[37]  T. Langmann,et al.  Mutations in the human ATP‐binding cassette transporters ABCG5 and ABCG8 in sitosterolemia , 2002, Human mutation.

[38]  S. Reis,et al.  APOE polymorphism and angiographic coronary artery disease severity in the Women's Ischemia Syndrome Evaluation (WISE) study. , 2003, Atherosclerosis.

[39]  E. Topol,et al.  Mutation of MEF2A in an Inherited Disorder with Features of Coronary Artery Disease , 2003, Science.

[40]  Daniel W. Jones,et al.  The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. , 2003, JAMA.

[41]  E. Topol,et al.  Thrombospondin-4 and Its Variants: Expression and Differential Effects on Endothelial Cells , 2003, Circulation.

[42]  A. Marais Familial hypercholesterolaemia. , 2004, The Clinical biochemist. Reviews.

[43]  I. Fearnley,et al.  The Phosphorylation of Subunits of Complex I from Bovine Heart Mitochondria* , 2004, Journal of Biological Chemistry.

[44]  A. Lusis,et al.  Effect of macrophage-derived apolipoprotein E on hyperlipidemia and atherosclerosis of LDLR-deficient mice. , 2004, Biochemical and biophysical research communications.

[45]  E. Topol,et al.  Transcription factor MEF2A mutations in patients with coronary artery disease. , 2004, Human molecular genetics.

[46]  Yusuke Nakamura,et al.  Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-α secretion in vitro , 2004, Nature.

[47]  T. Hirao Disability‐adjusted life expectancy: Is it useful? , 2004 .

[48]  Gudmundur A. Thorisson,et al.  The International HapMap Project Web site. , 2005, Genome research.

[49]  P. Poole‐Wilson,et al.  5-year outcome of an interventional strategy in non-ST-elevation acute coronary syndrome: the British Heart Foundation RITA 3 randomised trial , 2005, The Lancet.

[50]  E. Topol,et al.  Identification of four gene variants associated with myocardial infarction. , 2005, American journal of human genetics.

[51]  P. Libby,et al.  Pathophysiology of Coronary Artery Disease , 2005, Circulation.

[52]  N. Chaturvedi,et al.  Heart disease epidemic in Pakistan: women and men at equal risk. , 2005, American heart journal.

[53]  U. Thorsteinsdóttir,et al.  Association between the gene encoding 5-lipoxygenase-activating protein and stroke replicated in a Scottish population. , 2005, American journal of human genetics.

[54]  P. Burton,et al.  A genomewide linkage study of 1,933 families affected by premature coronary artery disease: The British Heart Foundation (BHF) Family Heart Study. , 2005, American journal of human genetics.

[55]  William Stafford Noble,et al.  Quantifying similarity between motifs , 2007, Genome Biology.

[56]  Alan D. Lopez,et al.  Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data , 2006, The Lancet.

[57]  Jonathan C. Cohen,et al.  Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. , 2006, The New England journal of medicine.

[58]  R. Collins,et al.  Genome-Wide Mapping of Susceptibility to Coronary Artery Disease Identifies a Novel Replicated Locus on Chromosome 17 , 2006, PLoS genetics.

[59]  G. Abecasis,et al.  Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies , 2006, Nature Genetics.

[60]  T. Hudson,et al.  Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol. , 2007, American journal of human genetics.

[61]  C. Gieger,et al.  Genomewide association analysis of coronary artery disease. , 2007, The New England journal of medicine.

[62]  N. Pedersen,et al.  Genetic influences on angina pectoris and its impact on coronary heart disease , 2007, European Journal of Human Genetics.

[63]  Inna Dubchak,et al.  VISTA Enhancer Browser—a database of tissue-specific human enhancers , 2006, Nucleic Acids Res..

[64]  R. Luben,et al.  Apolipoprotein E polymorphisms, dietary fat and fibre, and serum lipids: the EPIC Norfolk study. , 2007, European heart journal.

[65]  E. Enas,et al.  Dyslipidemia in South Asian patients , 2007, Current atherosclerosis reports.

[66]  P. Grant Diabetes mellitus as a prothrombotic condition , 2007, Journal of internal medicine.

[67]  A. Gylfason,et al.  A Common Variant on Chromosome 9p21 Affects the Risk of Myocardial Infarction , 2007, Science.

[68]  S. Yusuf,et al.  Global burden of cardiovascular disease , 2007, Heart.

[69]  T. Jafar,et al.  Coronary artery disease epidemic in Pakistan: more electrocardiographic evidence of ischaemia in women than in men , 2007, Heart.

[70]  M. McCarthy,et al.  Genome-wide association studies for complex traits: consensus, uncertainty and challenges , 2008, Nature Reviews Genetics.

[71]  T. Furey,et al.  A general integrative genomic feature transcription factor binding site prediction method applied to analysis of USF1 binding in cardiovascular disease , 2009, Human Genomics.

[72]  Brad T. Sherman,et al.  Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.

[73]  P. Huber,et al.  Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis. , 2008, Biochimica et biophysica acta.

[74]  Andrew D. Johnson,et al.  SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap , 2008, Bioinform..

[75]  M. Bodén,et al.  Associating transcription factor-binding site motifs with target GO terms and target genes , 2008, Nucleic acids research.

[76]  K. Furie,et al.  Heart disease and stroke statistics--2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. , 2007, Circulation.

[77]  Judy H. Cho,et al.  Finding the missing heritability of complex diseases , 2009, Nature.

[78]  R. Collins,et al.  Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies , 2009, The Lancet.

[79]  Daniel F. Schwarz,et al.  New susceptibility locus for coronary artery disease on chromosome 3q22.3 , 2009, Nature Genetics.

[80]  T. Hudson,et al.  Genetic Variants Associated With Myocardial Infarction Risk Factors in Over 8000 Individuals From Five Ethnic Groups: The INTERHEART Genetics Study , 2009, Circulation. Cardiovascular genetics.

[81]  P. Greenland Time for the medical profession to act: new policies needed now on interactions between pharmaceutical companies and physicians. , 2009, Archives of internal medicine.

[82]  Anping Chen,et al.  Curcumin suppresses expression of low‐density lipoprotein (LDL) receptor, leading to the inhibition of LDL‐induced activation of hepatic stellate cells , 2009, British journal of pharmacology.

[83]  D. Postma,et al.  Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction , 2009, Nature Genetics.

[84]  R. Collins,et al.  Common variants at 30 loci contribute to polygenic dyslipidemia , 2009, Nature Genetics.

[85]  S. Yusuf,et al.  Relationship of the ApoE polymorphism to plasma lipid traits among South Asians, Chinese, and Europeans living in Canada. , 2009, Atherosclerosis.

[86]  R. Collins,et al.  Genetic variants associated with Lp(a) lipoprotein level and coronary disease. , 2009, The New England journal of medicine.

[87]  P. Deloukas,et al.  Large Scale Association Analysis of Novel Genetic Loci for Coronary Artery Disease , 2009, Arteriosclerosis, thrombosis, and vascular biology.

[88]  Mikael Bodén,et al.  Assigning roles to DNA regulatory motifs using comparative genomics , 2010, Bioinform..

[89]  Jason H. Moore,et al.  Missing heritability and strategies for finding the underlying causes of complex disease , 2010, Nature Reviews Genetics.

[90]  G. Bakris,et al.  Tight blood pressure control and cardiovascular outcomes among hypertensive patients with diabetes and coronary artery disease. , 2010, JAMA.

[91]  L. Lloyd,et al.  Childhood obesity and adult cardiovascular disease risk: a systematic review , 2010, International Journal of Obesity.

[92]  K. Siddiqi,et al.  Local Determinants of Tobacco Use in Pakistan and the Importance of Context , 2010 .

[93]  M. Pepe,et al.  The Potential of Genes and Other Markers to Inform about Risk , 2010, Cancer Epidemiology, Biomarkers & Prevention.

[94]  Nathaniel D. Heintzman,et al.  9p21 DNA variants associated with Coronary Artery Disease impair IFNγ signaling response , 2011, Nature.

[95]  Y. Fujiwara,et al.  Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations. , 2011, Atherosclerosis.

[96]  C. Gieger,et al.  Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23. , 2011, European heart journal.

[97]  P. Libby,et al.  Progress and challenges in translating the biology of atherosclerosis , 2011, Nature.

[98]  Simon C. Potter,et al.  Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease , 2011, PLoS genetics.

[99]  明石 昌也 A coronary artery disease-associated gene product, JCAD/KIAA1462, is a novel component of endothelial cell-cell junctions , 2011 .

[100]  Qing Yang,et al.  Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population , 2011, Nature Genetics.

[101]  E. Nabel,et al.  Genomics of cardiovascular disease. , 2011, The New England journal of medicine.

[102]  Masasuke Yoshida,et al.  Knockdown of DAPIT (Diabetes-associated Protein in Insulin-sensitive Tissue) Results in Loss of ATP Synthase in Mitochondria , 2011, The Journal of Biological Chemistry.

[103]  N. Mehta Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. , 2011, Circulation. Cardiovascular genetics.

[104]  T. Assimes,et al.  Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies , 2011, The Lancet.

[105]  L. F. A. Marrzoq,et al.  Relationship between ApoE gene polymorphism and coronary heart disease in Gaza Strip , 2011, Journal of cardiovascular disease research.

[106]  E. Topol,et al.  Emerging genomic applications in coronary artery disease. , 2011, JACC. Cardiovascular interventions.

[107]  Inna Dubchak,et al.  VISTA Region Viewer (RViewer) - a computational system for prioritizing genomic intervals for biomedical studies , 2011, Bioinform..

[108]  Jason H. Moore,et al.  Chapter 11: Genome-Wide Association Studies , 2012, PLoS Comput. Biol..

[109]  F. Ippoliti,et al.  Cellular and molecular players in the atherosclerotic plaque progression , 2012, Annals of the New York Academy of Sciences.

[110]  T. Ogihara,et al.  Genome-wide association study of coronary artery disease in the Japanese , 2011, European Journal of Human Genetics.

[111]  A. Marian Molecular genetic studies of complex phenotypes. , 2012, Translational research : the journal of laboratory and clinical medicine.

[112]  T. Lüscher,et al.  Molecular mechanisms of vascular effects of High-density lipoprotein: alterations in cardiovascular disease , 2012, EMBO molecular medicine.

[113]  Jake K. Byrnes,et al.  Bayesian refinement of association signals for 14 loci in 3 common diseases , 2012, Nature Genetics.

[114]  T. Spector,et al.  Understanding coronary artery disease using twin studies , 2012, Heart.

[115]  Natalie de Souza The ENCODE project , 2012, Nature Methods.

[116]  Rafael C. Jimenez,et al.  The IntAct molecular interaction database in 2012 , 2011, Nucleic Acids Res..

[117]  Andre Franke,et al.  1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data , 2012, European Journal of Human Genetics.

[118]  Eurie L. Hong,et al.  Annotation of functional variation in personal genomes using RegulomeDB , 2012, Genome research.

[119]  P. Malani Harrison’s Principles of Internal Medicine , 2012 .

[120]  D. Francis,et al.  Mortality from ischaemic heart disease by country, region, and age: Statistics from World Health Organisation and United Nations , 2013, International journal of cardiology.

[121]  J. Danesh,et al.  Large-scale association analysis identifies new risk loci for coronary artery disease , 2013 .

[122]  P. D. Zende,et al.  Apolipoprotein e gene polymorphism and its effect on plasma lipids in arteriosclerosis. , 2013, Journal of clinical and diagnostic research : JCDR.

[123]  V. Fuster,et al.  Histopathologic characteristics of atherosclerotic coronary disease and implications of the findings for the invasive and noninvasive detection of vulnerable plaques. , 2013, Journal of the American College of Cardiology.

[124]  Yan-wei Yin,et al.  Association between Apolipoprotein E Gene Polymorphism and the Risk of Coronary Artery Disease in Chinese Population: Evidence from a Meta-Analysis of 40 Studies , 2013, PloS one.

[125]  Ruoling Chen,et al.  South Asians and coronary disease: is there discordance between effects on incidence and prognosis? , 2013, Heart.

[126]  M. Budoff,et al.  Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study: Objectives, Methods, and Cohort Description , 2013, Clinical cardiology.

[127]  Mark D. Huffman,et al.  Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart Association. , 2013, Circulation.

[128]  A. Aggarwal,et al.  Cardiovascular Risk Factors in Young Patients of Coronary Artery Disease: Differences over a Decade , 2014, Journal of cardiovascular and thoracic research.

[129]  David J. Arenillas,et al.  JASPAR 2014: an extensively expanded and updated open-access database of transcription factor binding profiles , 2013, Nucleic Acids Res..

[130]  C. Murray,et al.  Variations in ischemic heart disease burden by age, country, and income: the Global Burden of Diseases, Injuries, and Risk Factors 2010 study. , 2014, Global heart.

[131]  Sonia S Anand,et al.  Cardiovascular disease in Asian Americans: unmasking heterogeneity. , 2014, Journal of the American College of Cardiology.

[132]  R. Roberts Genetics of coronary artery disease: an update. , 2014, Methodist DeBakey cardiovascular journal.

[133]  B. Snitz,et al.  Association of APOE polymorphisms and stressful life events with dementia in a Pakistani population , 2014, Neuroscience Letters.

[134]  S. Lerakis,et al.  New and Emerging Risk Factors for Coronary Heart Disease , 2014, The American journal of the medical sciences.

[135]  P. Scarborough,et al.  Corrigendum to: cardiovascular disease in Europe 2014: epidemiological update. , 2015, European heart journal.

[136]  J. Danesh,et al.  A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease , 2016 .

[137]  Yusuke Nakamura,et al.  A genome-wide association study identifies PLCL2 and AP3D1-DOT1L-SF3A2 as new susceptibility loci for myocardial infarction in Japanese , 2022 .

[138]  Coronary artery dimensions: Iranian population versus Indo-Asians and Caucasians , 2015, Asian cardiovascular & thoracic annals.

[139]  Á. Avezum,et al.  Cardiovascular Disease Burden: Evolving Knowledge of Risk Factors in Myocardial Infarction and Stroke through Population-Based Research and Perspectives in Global Prevention , 2015, Front. Cardiovasc. Med..

[140]  Sonia S Anand,et al.  Cardiovascular Disease in South Asian Migrants. , 2015, The Canadian journal of cardiology.

[141]  B. Litschauer,et al.  Physical inactivity increases endostatin and osteopontin in patients with coronary artery disease , 2016, Heart and Vessels.

[142]  Asma N. Cheema,et al.  APOE Gene Polymorphism and Risk of Coronary Stenosis in Pakistani Population , 2015, BioMed research international.

[143]  C. Foster,et al.  The physical activity profiles of South Asian ethnic groups in England , 2015, Journal of Epidemiology & Community Health.

[144]  C. Fischbacher,et al.  Ethnicity and risk of cardiovascular disease (CVD): 4.8 year follow-up of patients with type 2 diabetes living in Scotland , 2015, Diabetologia.

[145]  Kengo Kinoshita,et al.  COXPRESdb in 2015: coexpression database for animal species by DNA-microarray and RNAseq-based expression data with multiple quality assessment systems , 2014, Nucleic Acids Res..

[146]  K. Bibbins-Domingo,et al.  Global Overview of the Epidemiology of Atherosclerotic Cardiovascular Disease. , 2015, Archives of medical research.

[147]  John E. Hall,et al.  Guyton and Hall Textbook of Medical Physiology , 2015 .

[148]  C. Gieger,et al.  Genetic Evidence for PLASMINOGEN as a Shared Genetic Risk Factor of Coronary Artery Disease and Periodontitis , 2015, Circulation. Cardiovascular genetics.

[149]  Tanya M. Teslovich,et al.  The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study , 2015, PLoS Genetics.

[150]  R. Feldman Heart Disease in Women: Unappreciated Challenges, GPER as a New Target , 2016, International journal of molecular sciences.

[151]  R. Zweiker,et al.  Hypertension and coronary artery disease: epidemiology, physiology, effects of treatment, and recommendations , 2016, Wiener klinische Wochenschrift.

[152]  F. Dudbridge Polygenic Epidemiology , 2016, Genetic epidemiology.

[153]  C. Varma,et al.  Epidemiology and pathogenesis of diffuse obstructive coronary artery disease: the role of arterial stiffness, shear stress, monocyte subsets and circulating microparticles , 2016, Annals of medicine.

[154]  David J. Arenillas,et al.  JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles , 2015, Nucleic Acids Res..

[155]  Shu-guang Lin,et al.  Ischemic heart disease deaths, disability-adjusted life years and risk factors in Fujian, China during 1990-2013: Data from the Global Burden of Disease Study 2013. , 2016, International journal of cardiology.