Diversion of Flux toward Sesquiterpene Production in Saccharomyces cerevisiae by Fusion of Host and Heterologous Enzymes
暂无分享,去创建一个
Jens Nielsen | Line Albertsen | Jerome Maury | J. Nielsen | U. Mortensen | J. Maury | S. Brix | Yun Chen | Stig Rattleff | Yun Chen | Lars S. Bach | Stig Rattleff | Susanne Brix | Uffe H. Mortensen | L. Albertsen | L. Bach
[1] A. Kondo,et al. Overproduction of Geranylgeraniol by Metabolically Engineered Saccharomyces cerevisiae , 2009, Applied and Environmental Microbiology.
[2] M. Schalk,et al. Redirection of cytosolic or plastidic isoprenoid precursors elevates terpene production in plants , 2006, Nature Biotechnology.
[3] A. Shearer,et al. Lipid‐mediated, reversible misfolding of a sterol‐sensing domain protein , 2005, The EMBO journal.
[4] J. Sambrook,et al. Molecular Cloning: A Laboratory Manual , 2001 .
[5] Jens Nielsen,et al. Production of plant sesquiterpenes in Saccharomyces cerevisiae: Effect of ERG9 repression on sesquiterpene biosynthesis , 2008, Biotechnology and bioengineering.
[6] Kirsten Jørgensen,et al. Metabolon formation and metabolic channeling in the biosynthesis of plant natural products. , 2005, Current opinion in plant biology.
[7] Patrik R. Jones,et al. Metabolon formation in dhurrin biosynthesis. , 2008, Phytochemistry.
[8] G. Stephanopoulos. Metabolic fluxes and metabolic engineering. , 1999, Metabolic engineering.
[9] K. Cho,et al. Evaluation of a novel bifunctional xylanase–cellulase constructed by gene fusion , 2005 .
[10] G. Palamarczyk,et al. Dolichol biosynthesis in the yeast Saccharomyces cerevisiae: an insight into the regulatory role of farnesyl diphosphate synthase. , 2002, FEMS yeast research.
[11] L. Bülow. Characterization of an artificial bifunctional enzyme, beta-galactosidase/galactokinase, prepared by gene fusion. , 1987, European journal of biochemistry.
[12] J Ovádi,et al. Metabolic consequences of enzyme interactions , 1996, Cell biochemistry and function.
[13] C. Olsen,et al. De Novo Biosynthesis of Vanillin in Fission Yeast (Schizosaccharomyces pombe) and Baker's Yeast (Saccharomyces cerevisiae) , 2009, Applied and Environmental Microbiology.
[14] Fan Xue,et al. LINKER: a web server to generate peptide sequences with extended conformation , 2004, Nucleic Acids Res..
[15] M. Brodelius,et al. Fusion of farnesyldiphosphate synthase and epi-aristolochene synthase, a sesquiterpene cyclase involved in capsidiol biosynthesis in Nicotiana tabacum. , 2002, European journal of biochemistry.
[16] Robert J. D. Reid,et al. Cloning-free genome alterations in Saccharomyces cerevisiae using adaptamer-mediated PCR. , 2002, Methods in enzymology.
[17] Jeffrey D Varner,et al. Engineering the spatial organization of metabolic enzymes: mimicking nature's synergy. , 2008, Current opinion in biotechnology.
[18] Jens Nielsen,et al. Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae , 2010, Biotechnology and bioengineering.
[19] R. Zahler. Enzyme Structure and Mechanism , 1979, The Yale Journal of Biology and Medicine.
[20] M. Feng,et al. Bifunctional enhancement of a β-glucanase-xylanase fusion enzyme by optimization of peptide linkers , 2008, Applied Microbiology and Biotechnology.
[21] Wouter de Laat,et al. Linker length and composition influence the flexibility of Oct‐1 DNA binding , 1997, The EMBO journal.
[22] K. Snell,et al. A novel thiolase-reductase gene fusion promotes the production of polyhydroxybutyrate in Arabidopsis. , 2005, Plant biotechnology journal.
[23] M. L. Nielsen,et al. Transient Marker System for Iterative Gene Targeting of a Prototrophic Fungus , 2007, Applied and Environmental Microbiology.
[24] C. Isarankura-Na-Ayudhya,et al. NAD(H) recycling activity of an engineered bifunctional enzyme galactose dehydrogenase/lactate dehydrogenase , 2006, International journal of biological sciences.
[25] K. Patil,et al. Enhancing sesquiterpene production in Saccharomyces cerevisiae through in silico driven metabolic engineering. , 2009, Metabolic engineering.
[26] M. Schalk,et al. The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases. , 2006, Archives of biochemistry and biophysics.
[27] G. Carman,et al. The LPP1 and DPP1 Gene Products Account for Most of the Isoprenoid Phosphate Phosphatase Activities inSaccharomyces cerevisiae * , 1999, The Journal of Biological Chemistry.
[28] Enhanced Stress Tolerance in Escherichia coli and Nicotiana tabacum Expressing a Betaine Aldehyde Dehydrogenase/Choline Dehydrogenase Fusion Protein , 2002, Biotechnology progress.
[29] Y. Koo,et al. Characterization of a Bifunctional Enzyme Fusion of Trehalose-6-Phosphate Synthetase and Trehalose-6-Phosphate Phosphatase of Escherichia coli , 2000, Applied and Environmental Microbiology.
[30] P. Sung,et al. Interaction with RPA Is Necessary for Rad52 Repair Center Formation and for Its Mediator Activity* , 2008, Journal of Biological Chemistry.
[31] T. Stachelhaus,et al. Harnessing the potential of communication-mediating domains for the biocombinatorial synthesis of nonribosomal peptides. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[32] W. A. Scheffers,et al. Physiology of Saccharomyces cerevisiae in anaerobic glucose-limited chemostat cultures. , 1990, Journal of general microbiology.
[33] G. Fink,et al. Laboratory course manual for methods in yeast genetics , 1986 .
[34] R. Sauer,et al. Optimizing the stability of single-chain proteins by linker length and composition mutagenesis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[35] Y. Sakai,et al. Bifunctional enzyme fusion of 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase , 2007, Applied Microbiology and Biotechnology.
[36] Gabriel C. Wu,et al. Synthetic protein scaffolds provide modular control over metabolic flux , 2009, Nature Biotechnology.
[37] Irwin A. Rose,et al. Enzyme structure and mechanism (2nd edn): by Alan Fersht, W. H. Freeman & Co., 1985. £14.95 pbk, £28.95 hbk (xxi + 475 pages) ISBN 0 7167 1615 1 , 1985 .
[38] L. Bülow,et al. Physical and kinetic effects on induction of various linker regions in beta-galactosidase/galactose dehydrogenase fusion enzymes. , 1996, Biochimica et biophysica acta.