Gallacher, Christopher and Thomas, Russell and Taylor, Christopher and Lord, Richard and Kalin, Robert M. (2017) Comprehensive composition of creosote using comprehensive two-dimensional gas chromatography

12 Creosote is a distillation product of coal tar and is widely used as wood preservative 13 for railway sleepers, utility poles and for other applications. Creosote can have 14 potentially negative effects on the environment and many of the components are toxic. 15 This study presents the analysis of a Creosote sample from a former wood 16 impregnation plant located in the UK. The sample was analysed using two 17 dimensional gas chromatography time-of-flight mass spectrometry (GCxGC-TOFMS) 18 and a database of compounds that could be detected was produced. The GCxGG19 TOFMS was capable of detecting 1505 individual compounds, which is far more than 20 previous estimates for the number of compounds present within Creosote. Post 21 extraction derivatization using BTSFA with 1% TMCS was employed to increase the 22 potential number of compounds detected with 255 derivatized compounds detected, 23 231 of which would not have been detected without prior derivatization. Selected 24 derivatized compounds were quantified with limits of detection ranging from 25

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