Good agreement between minimal erythema dose test reactions and objective measurements: an in vivo study of human skin

The erythema resulting from the minimal erythema dose (MED) test is subjectively assessed. The evaluator visually grades erythema on an ordinal scale. Both intra‐ and interobserver variation have been found for this erythema assessment. We wanted to examine if objective measurements could be used to confirm the subjective finding.

[1]  H. Muller,et al.  Ultraviolet light induced injury: Immunological and inflammatory effects , 2001, Immunology and cell biology.

[2]  N. Sans,et al.  High-resolution magnetic resonance imaging in study of the skin: normal patterns. , 2011, European journal of radiology.

[3]  Masato Hatao,et al.  Objective Measurement of Minimal Erythema and Melanogenic Doses Using Natural and Solar-simulated Light¶ , 2003, Photochemistry and photobiology.

[4]  H. Wulf,et al.  Pheomelanin and eumelanin in human skin determined by high‐performance liquid chromatography and its relation to in vivo reflectance measurements , 2006, Photodermatology, photoimmunology & photomedicine.

[5]  H. Wulf,et al.  Epidermal thickness at different body sites: relationship to age, gender, pigmentation, blood content, skin type and smoking habits. , 2003, Acta dermato-venereologica.

[6]  K. Wilhelm,et al.  Comparison of three techniques for evaluating skin erythemal response for determination of sun protection factors of sunscreens: high resolution laser Doppler imaging, colorimetry and visual scoring , 2001, Photodermatology, photoimmunology & photomedicine.

[7]  C. Anderson,et al.  Inter‐observer variability in reading of phototest reactions with sharply or diffusely delineated borders , 2008, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[8]  H. Wulf,et al.  UV induced erythema evaluated 24 h post-exposure by skin reflectance and laser Doppler flowmetry is identical in healthy persons and patients with cutaneous malignant melanoma and basal cell cancer. , 1997, Journal of photochemistry and photobiology. B, Biology.

[9]  N. Kollias,et al.  In vivo measurement of skin erythema and pigmentation: new means of implementation of diffuse reflectance spectroscopy with a commercial instrument , 2008, The British journal of dermatology.

[10]  R. Ikäheimo,et al.  Validation of a new dielectric device to assess changes of tissue water in skin and subcutaneous fat. , 2004, Physiological measurement.

[11]  K. Wårdell,et al.  Phototesting based on a divergent beam – a study on normal subjects , 2001, Photodermatology, photoimmunology & photomedicine.

[12]  Young-Hun Kim,et al.  Comparative Study of the Gross Interpretation of Phototesting and Objective Measurement with Using a Spectrophotometer for Patients with Psoriasis and Vitiligo Treated with Narrow-band UVB. , 2009, Annals of dermatology.

[13]  B L Diffey,et al.  Quantitative aspects of ultraviolet erythema. , 1991, Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics.

[14]  H. Wulf,et al.  Threshold level for measurement of UV sensitivity: reproducibility of phototest , 1996, Photodermatology, photoimmunology & photomedicine.

[15]  Vinod K. Sharma,et al.  Determination of minimal erythemal dose for narrow band-ultraviolet B radiation in north Indian patients: comparison of visual and Dermaspectrometer readings. , 2007, Indian journal of dermatology, venereology and leprology.