Human endogenous retrovirus W env increases nitric oxide production and enhances the migration ability of microglia by regulating the expression of inducible nitric oxide synthase

[1]  N. Lou,et al.  Hepatitis C virus NS3 protein enhances hepatocellular carcinoma cell invasion by promoting PPM1A ubiquitination and degradation , 2017, Journal of Experimental & Clinical Cancer Research.

[2]  Junyang Jung,et al.  Nitric Oxide: Exploring the Contextual Link with Alzheimer's Disease , 2016, Oxidative medicine and cellular longevity.

[3]  J. Fuseler,et al.  Nitric Oxide Modulates Postnatal Bone Marrow-Derived Mesenchymal Stem Cell Migration , 2016, Front. Cell Dev. Biol..

[4]  Rong Li,et al.  MiRNA-Embedded ShRNAs for Radiation-Inducible LGMN Knockdown and the Antitumor Effects on Breast Cancer , 2016, PloS one.

[5]  P. Zhou,et al.  Elevation of Ser9 phosphorylation of GSK3β is required for HERV-W env-mediated BDNF signaling in human U251 cells , 2016, Neuroscience Letters.

[6]  Heng Zhang,et al.  Effects of nitric oxide on the biological behavior of HepG2 human hepatocellular carcinoma cells. , 2016, Experimental and therapeutic medicine.

[7]  J. Chao,et al.  iNOS Induces Vascular Endothelial Cell Migration and Apoptosis Via Autophagy in Ischemia/Reperfusion Injury , 2016, Cellular Physiology and Biochemistry.

[8]  H. Komano,et al.  ATP increases the migration of microglia across the brain endothelial cell monolayer , 2016, Bioscience reports.

[9]  V. Kostic,et al.  Why is nitric oxide important for our brain? , 2015, Functional neurology.

[10]  Libo Wang,et al.  The role of eNOS in the migration and proliferation of bone‐marrow derived endothelial progenitor cells and in vitro angiogenesis , 2015, Cell biology international.

[11]  A. Fatemi,et al.  Pathologic role of glial nitric oxide in adult and pediatric neuroinflammatory diseases , 2014, Neuroscience & Biobehavioral Reviews.

[12]  T. Liu,et al.  Mutations in 3′-long terminal repeat of HERV-W family in chromosome 7 upregulate syncytin-1 expression in urothelial cell carcinoma of the bladder through interacting with c-Myb , 2014, Oncogene.

[13]  M. Stern,et al.  Nitric oxide/cyclic GMP signaling regulates motility of a microglial cell line and primary microglia in vitro , 2014, Brain Research.

[14]  Y. T. Chen,et al.  Human endogenous retrovirus W family envelope gene activates the small conductance Ca2+-activated K+ channel in human neuroblastoma cells through CREB , 2013, Neuroscience.

[15]  J. Cheong,et al.  Synergistic activation of lipopolysaccharide-stimulated glial cells by propofol. , 2013, Biochemical and Biophysical Research Communications - BBRC.

[16]  Hui Li,et al.  Insulin inhibits lipopolysaccharide-induced nitric oxide synthase expression in rat primary astrocytes , 2013, Brain Research.

[17]  S. Lipton,et al.  Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death in neurodegenerative diseases , 2012, Experimental Neurology.

[18]  L. Nicholson,et al.  AGEs–RAGE mediated up-regulation of connexin43 in activated human microglial CHME-5 cells , 2012, Neurochemistry International.

[19]  L. Farinelli,et al.  Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease , 2012, Multiple sclerosis.

[20]  Yongchang Chen,et al.  Nitric oxide inhibits gastric cancer cell growth through the modulation of the Akt pathway. , 2011, Molecular medicine reports.

[21]  F. Zhu,et al.  Implication of the env gene of the human endogenous retrovirus W family in the expression of BDNF and DRD3 and development of recent-onset schizophrenia. , 2011, Schizophrenia bulletin.

[22]  P. Gressens,et al.  The Yin and Yang of Microglia , 2011, Developmental Neuroscience.

[23]  F. Mallet,et al.  Custom human endogenous retroviruses dedicated microarray identifies self-induced HERV-W family elements reactivated in testicular cancer upon methylation control , 2010, Nucleic acids research.

[24]  C. Colton Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain , 2009, Journal of Neuroimmune Pharmacology.

[25]  C. Savage,et al.  Characterisation of K+ Currents in the C8-B4 Microglial Cell Line and their Regulation by Microglia Activating Stimuli , 2009, Cellular Physiology and Biochemistry.

[26]  S. Snyder,et al.  Signaling by Gasotransmitters , 2009, Science Signaling.

[27]  Jianguo Wu,et al.  Negative feedback regulation of IL‐32 production by iNOS activation in response to dsRNA or influenza virus infection , 2009, European journal of immunology.

[28]  H. Kettenmann,et al.  Microglia: active sensor and versatile effector cells in the normal and pathologic brain , 2007, Nature Neuroscience.

[29]  C. Power,et al.  The Human Endogenous Retrovirus Envelope Glycoprotein, Syncytin-1, Regulates Neuroinflammation and Its Receptor Expression in Multiple Sclerosis: A Role for Endoplasmic Reticulum Chaperones in Astrocytes1 , 2007, The Journal of Immunology.

[30]  P. Mcgeer,et al.  Therapeutic approaches to inflammation in neurodegenerative disease , 2007, Current opinion in neurology.

[31]  Yan Liu,et al.  Retinoic acid activates human inducible nitric oxide synthase gene through binding of RARalpha/RXRalpha heterodimer to a novel retinoic acid response element in the promoter. , 2007, Biochemical and biophysical research communications.

[32]  Frauke Zipp,et al.  The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases , 2006, Trends in Neurosciences.

[33]  I. Christensen,et al.  Syncytin is involved in breast cancer-endothelial cell fusions , 2006, Cellular and Molecular Life Sciences CMLS.

[34]  R. N. Saha,et al.  Signals for the induction of nitric oxide synthase in astrocytes , 2006, Neurochemistry International.

[35]  R. N. Saha,et al.  Regulation of inducible nitric oxide synthase gene in glial cells. , 2006, Antioxidants & redox signaling.

[36]  Gao-Hua Wang,et al.  Human endogenous retroviral pol RNA and protein detected and identified in the blood of individuals with schizophrenia , 2006, Schizophrenia Research.

[37]  J. Wallace Nitric oxide as a regulator of inflammatory processes. , 2005, Memorias do Instituto Oswaldo Cruz.

[38]  J. Hauw,et al.  Human endogenous retrovirus (HERV)-W ENV and GAG proteins: Physiological expression in human brain and pathophysiological modulation in multiple sclerosis lesions , 2005, Journal of NeuroVirology.

[39]  D. Butterfield,et al.  Human endogenous retrovirus glycoprotein–mediated induction of redox reactants causes oligodendrocyte death and demyelination , 2004, Nature Neuroscience.

[40]  J. Blomberg,et al.  Definition and variation of human endogenous retrovirus H. , 2004, Virology.

[41]  L. Duret,et al.  The endogenous retroviral locus ERVWE1 is a bona fide gene involved in hominoid placental physiology. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[42]  M. Vidaud,et al.  Direct Involvement of HERV-W Env Glycoprotein in Human Trophoblast Cell Fusion and Differentiation , 2003, Molecular and Cellular Biology.

[43]  J. Clausen Endogenous retroviruses and MS: using ERVs as disease markers. , 2003, International MS journal.

[44]  C. Cooper,et al.  Nitric oxide synthases: structure, function and inhibition. , 2001, The Biochemical journal.

[45]  T. Kasahara,et al.  Nitric oxide induces chemotaxis of neutrophil-like HL-60 cells and translocation of cofilin to plasma membranes. , 2000, International journal of immunopharmacology.

[46]  J. Mccoy,et al.  Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis , 2000, Nature.

[47]  H. Kettenmann,et al.  Induction of potassium channels in mouse brain microglia: cells acquire responsiveness to pneumococcal cell wall components during late development , 1999, Neuroscience.

[48]  A. M. Lefer,et al.  II. Nitric oxide protects in intestinal inflammation. , 1999, American journal of physiology. Gastrointestinal and liver physiology.

[49]  T. Werner,et al.  Proviral Structure, Chromosomal Location, and Expression of HERV-K-T47D, a Novel Human Endogenous Retrovirus Derived from T47D Particles , 1998, Journal of Virology.

[50]  B. Conrad,et al.  A Human Endogenous Retroviral Superantigen as Candidate Autoimmune Gene in Type I Diabetes , 1997, Cell.

[51]  C. Voisset,et al.  Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[52]  T. Dawson,et al.  Nitric oxide in health and disease of the nervous system , 1997, Molecular Psychiatry.

[53]  V. Brusic,et al.  Direct evidence for the expression of multiple endogenous retroviruses in the synovial compartment in rheumatoid arthritis. , 1997, Arthritis and rheumatism.

[54]  J. Mudgett,et al.  Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[55]  K. H. Ng,et al.  Establishment of human microglial cell lines after transfection of primary cultures of embryonic microglial cells with the SV40 large T antigen , 1995, Neuroscience Letters.

[56]  E. Torrey,et al.  Viruses, schizophrenia, and bipolar disorder , 1995, Clinical microbiology reviews.

[57]  D. Reis,et al.  Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[58]  R. Singh,et al.  Therapeutic role of nitric oxide as emerging molecule. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[59]  J. Zhu,et al.  CXCR7 suppression modulates microglial chemotaxis to ameliorate experimentally-induced autoimmune encephalomyelitis. , 2016, Biochemical and biophysical research communications.

[60]  D. Rosen,et al.  Expression of multiple human endogenous retrovirus surface envelope proteins in ovarian cancer , 2007, International journal of cancer.

[61]  S. Sotgiu,et al.  Brains and peripheral blood mononuclear cells of multiple sclerosis (MS) patients hyperexpress MS-associated retrovirus/HERV-W endogenous retrovirus, but not Human herpesvirus 6. , 2007, The Journal of general virology.

[62]  R. Yolken,et al.  HERV-W-related RNA detected in plasma from individuals with recent-onset schizophrenia or schizoaffective disorder , 2004, Molecular Psychiatry.

[63]  S. Snyder,et al.  Nitric oxide: a neural messenger. , 1995, Annual review of cell and developmental biology.

[64]  B. Foley,et al.  Expression of human endogenous retrovirus (HERV-K) in chronic myeloid leukemia. , 1993, Leukemia & lymphoma.