Structure of the Cardiac Sodium Channel
暂无分享,去创建一个
W. Catterall | N. Zheng | Yan Zhao | C. Yoshioka | T. M. G. El-Din | M. J. Lenaeus | Hui Shi | D. Jiang | L. Tonggu | M. Lenaeus
[1] W. Catterall,et al. Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel , 2019, Cell.
[2] N. Yan,et al. Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins , 2019, Science.
[3] Molecular basis for pore blockade of human Na+channel Nav1.2 by the mu-conotoxin KIIIA. , 2019 .
[4] N. Yan,et al. Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA , 2019, Science.
[5] Kevin R. DeMarco,et al. Structural basis for antiarrhythmic drug interactions with the human cardiac sodium channel , 2018, Proceedings of the National Academy of Sciences.
[6] W. Catterall,et al. Fenestrations control resting-state block of a voltage-gated sodium channel , 2018, Proceedings of the National Academy of Sciences.
[7] H. Gong,et al. Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1 , 2018, Science.
[8] Qiang Zhou,et al. Structure of the human voltage-gated sodium channel Nav1.4 in complex with beta1 , 2018 .
[9] J. Ge,et al. SCN5A Variants: Association With Cardiac Disorders , 2018, Front. Physiol..
[10] M. Chahine,et al. A New Cardiac Channelopathy: From Clinical Phenotypes to Molecular Mechanisms Associated With Nav1.5 Gating Pores , 2018, Front. Cardiovasc. Med..
[11] W. Catterall,et al. Structural Basis for Gating Pore Current in Periodic Paralysis , 2018, Nature.
[12] José María Carazo,et al. MonoRes: Automatic and Accurate Estimation of Local Resolution for Electron Microscopy Maps. , 2018, Structure.
[13] Alexis Rohou,et al. cisTEM: User-friendly software for single-particle image processing , 2017, bioRxiv.
[14] Jiahui Chen,et al. Improvements to the APBS biomolecular solvation software suite , 2017, Protein science : a publication of the Protein Society.
[15] W. Catterall. Voltage-Gated Sodium Channels and Electrical Excitability of the Heart , 2018 .
[16] William A Catterall,et al. The chemical basis for electrical signaling. , 2017, Nature chemical biology.
[17] B. Brooks,et al. Origin of pKa Shifts of Internal Lysine Residues in SNase Studied Via Equal-Molar VMMS Simulations in Explicit Water. , 2017, The journal of physical chemistry. B.
[18] D. Agard,et al. MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy , 2017, Nature Methods.
[19] Jianping Wu,et al. Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution , 2017, Science.
[20] M. Boutjdir,et al. Mutations in the Voltage Sensors of Domains I and II of Nav1.5 that are Associated with Arrhythmias and Dilated Cardiomyopathy Generate Gating Pore Currents , 2015, Front. Pharmacol..
[21] Kai Zhang,et al. Gctf: Real-time CTF determination and correction , 2015, bioRxiv.
[22] L. Isom,et al. Sodium channel β subunits: emerging targets in channelopathies. , 2015, Annual review of physiology.
[23] E. Gouaux,et al. Screening and large-scale expression of membrane proteins in mammalian cells for structural studies , 2014, Nature Protocols.
[24] W. Catterall,et al. Tracking S4 movement by gating pore currents in the bacterial sodium channel NaChBac , 2014, The Journal of general physiology.
[25] F. Bezanilla,et al. Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels , 2013, The Journal of general physiology.
[26] Christopher Ing,et al. Catalysis of Na+ permeation in the bacterial sodium channel NaVAb , 2013, Proceedings of the National Academy of Sciences.
[27] B. Chanda,et al. Multiple pore conformations driven by asynchronous movements of voltage sensors in a eukaryotic sodium channel , 2013, Nature Communications.
[28] Sjors H.W. Scheres,et al. RELION: Implementation of a Bayesian approach to cryo-EM structure determination , 2012, Journal of structural biology.
[29] V. Pande,et al. Marked difference in saxitoxin and tetrodotoxin affinity for the human nociceptive voltage-gated sodium channel (Nav1.7) , 2012, Proceedings of the National Academy of Sciences.
[30] William A. Catterall,et al. Crystal structure of a voltage-gated sodium channel in two potentially inactivated states , 2012, Nature.
[31] M. Baker,et al. Outcome of the First Electron Microscopy Validation Task Force Meeting , 2012, Structure.
[32] David Baker,et al. Structural basis for gating charge movement in the voltage sensor of a sodium channel , 2011, Proceedings of the National Academy of Sciences.
[33] W. Catterall,et al. Gating charge interactions with the S1 segment during activation of a Na+ channel voltage sensor , 2011, Proceedings of the National Academy of Sciences.
[34] W. Catterall,et al. THE CRYSTAL STRUCTURE OF A VOLTAGE-GATED SODIUM CHANNEL , 2011, Nature.
[35] B. García-Moreno E.,et al. Large shifts in pKa values of lysine residues buried inside a protein , 2011, Proceedings of the National Academy of Sciences.
[36] P. Emsley,et al. Features and development of Coot , 2010, Acta crystallographica. Section D, Biological crystallography.
[37] Randy J. Read,et al. Acta Crystallographica Section D Biological , 2003 .
[38] J. Towbin,et al. An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing. , 2010, Heart rhythm.
[39] W. Catterall,et al. Sequential formation of ion pairs during activation of a sodium channel voltage sensor , 2009, Proceedings of the National Academy of Sciences.
[40] W. Catterall,et al. Depolarization-activated gating pore current conducted by mutant sodium channels in potassium-sensitive normokalemic periodic paralysis , 2008, Proceedings of the National Academy of Sciences.
[41] W. Catterall,et al. Disulfide locking a sodium channel voltage sensor reveals ion pair formation during activation , 2008, Proceedings of the National Academy of Sciences.
[42] Eric S. Silver,et al. A Novel and Lethal De Novo LQT-3 Mutation in a Newborn with Distinct Molecular Pharmacology and Therapeutic Response , 2007, PloS one.
[43] S. Cannon,et al. A Na+ Channel Mutation Linked to Hypokalemic Periodic Paralysis Exposes a Proton-selective Gating Pore , 2007, The Journal of general physiology.
[44] W. Catterall,et al. Gating pore current in an inherited ion channelopathy , 2007, Nature.
[45] Eric Gouaux,et al. Fluorescence-detection size-exclusion chromatography for precrystallization screening of integral membrane proteins. , 2006, Structure.
[46] T. Strom,et al. Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine , 2005, The Lancet.
[47] Anchi Cheng,et al. Automated molecular microscopy: the new Leginon system. , 2005, Journal of structural biology.
[48] Conrad C. Huang,et al. UCSF Chimera—A visualization system for exploratory research and analysis , 2004, J. Comput. Chem..
[49] O. Hauswirth,et al. Fast and slow blockade of sodium channels by flecainide in rabbit cardiac Purkinje fibres , 1990, Naunyn-Schmiedeberg's Archives of Pharmacology.
[50] G. Wang,et al. State-dependent Block of Wild-type and Inactivation-deficient Na+ Channels by Flecainide , 2003, The Journal of general physiology.
[51] R. Kass,et al. Common Molecular Determinants of Flecainide and Lidocaine Block of Heart Na+ Channels , 2003, The Journal of general physiology.
[52] R. Kass,et al. Mutations in Cardiac Sodium Channels , 2003, American journal of pharmacogenomics : genomics-related research in drug development and clinical practice.
[53] A. Four-Barrier. Ionic Selectivity, Saturation, and Block in Sodium Channels , 2003 .
[54] F. Bezanilla,et al. Tracking Voltage-dependent Conformational Changes in Skeletal Muscle Sodium Channel during Activation , 2002, The Journal of general physiology.
[55] Roland Contreras,et al. Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[56] Mohamed Chahine,et al. Expression and Intracellular Localization of an SCN5A Double Mutant R1232W/T1620M Implicated in Brugada Syndrome , 2002, Circulation research.
[57] D. Clapham,et al. A Prokaryotic Voltage-Gated Sodium Channel , 2001, Science.
[58] E. Bennett. Channel cytoplasmic loops alter voltage‐dependent sodium channel activation in an isoform‐specific manner , 2001, The Journal of physiology.
[59] A. Shrier,et al. Novel Mechanism for Brugada Syndrome: Defective Surface Localization of an SCN5A Mutant(R1432G) , 2001, Circulation research.
[60] W. Catterall,et al. From Ionic Currents to Molecular Mechanisms The Structure and Function of Voltage-Gated Sodium Channels , 2000, Neuron.
[61] Gail Mandel,et al. Nomenclature of Voltage-Gated Sodium Channels , 2000, Neuron.
[62] H. Fozzard,et al. A critical residue for isoform difference in tetrodotoxin affinity is a molecular determinant of the external access path for local anesthetics in the cardiac sodium channel. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[63] C. Rohl,et al. Solution structure of the sodium channel inactivation gate. , 1999, Biochemistry.
[64] W. Catterall,et al. A Critical Role for the S4-S5 Intracellular Loop in Domain IV of the Sodium Channel α-Subunit in Fast Inactivation* , 1998, The Journal of Biological Chemistry.
[65] Edward Moczydlowski,et al. On the Structural Basis for Size-selective Permeation of Organic Cations through the Voltage-gated Sodium Channel , 1997, The Journal of general physiology.
[66] A. L. Goldin,et al. Interaction between the sodium channel inactivation linker and domain III S4-S5. , 1997, Biophysical journal.
[67] S. Moss,et al. A single serine residue confers tetrodotoxin insensitivity on the rat sensory‐neuron‐specific sodium channel SNS , 1997, FEBS letters.
[68] L. Schild,et al. On the structural basis for ionic selectivity among Na+, K+, and Ca2+ in the voltage-gated sodium channel. , 1996, Biophysical journal.
[69] W. Catterall,et al. Movement of the Na+ Channel Inactivation Gate during Inactivation* , 1996, The Journal of Biological Chemistry.
[70] W. Catterall,et al. Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[71] H. Fozzard,et al. Structure and function of voltage-dependent sodium channels: comparison of brain II and cardiac isoforms. , 1996, Physiological reviews.
[72] R. Horn,et al. Molecular Basis of Charge Movement in Voltage-Gated Sodium Channels , 1996, Neuron.
[73] W. Catterall,et al. Structure and function of the β2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif , 1995, Cell.
[74] W. Catterall,et al. Modulation of Cardiac Na+ Channel Expression in Xenopus Oocytes by β1 Subunits (*) , 1995, The Journal of Biological Chemistry.
[75] A. George,et al. Molecular mechanism for an inherited cardiac arrhythmia , 1995, Nature.
[76] R. Horn,et al. Evidence for voltage-dependent S4 movement in sodium channels , 1995, Neuron.
[77] W. Catterall,et al. A Critical Role for Transmembrane Segment IVS6 of the Sodium Channel α Subunit in Fast Inactivation (*) , 1995, The Journal of Biological Chemistry.
[78] T. Scheuer,et al. A mutation in segment IVS6 disrupts fast inactivation of sodium channels. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[79] Lori L. Isom,et al. Auxiliary subunits of voltage-gated ion channels , 1994, Neuron.
[80] A. George,et al. Voltage-gated Na+ channel beta 1 subunit mRNA expressed in adult human skeletal muscle, heart, and brain is encoded by a single gene. , 1994, The Journal of biological chemistry.
[81] A L Goldin,et al. A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[82] W. Stühmer,et al. Calcium channel characteristics conferred on the sodium channel by single mutations , 1992, Nature.
[83] F. Conti,et al. Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II , 1991, FEBS letters.
[84] L. Hondeghem,et al. Interactions of flecainide with guinea pig cardiac sodium channels. Importance of activation unblocking to the voltage dependence of recovery. , 1990, Circulation research.
[85] W. Stühmer,et al. A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II , 1989, FEBS letters.
[86] R. Rogart,et al. Molecular cloning of a putative tetrodotoxin-resistant rat heart Na+ channel isoform. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[87] W. Catterall,et al. Biochemical properties of sodium channels in a wide range of excitable tissues studied with site-directed antibodies. , 1988, Biochemistry.
[88] M. Noda,et al. Molecular Structure of Sodium Channels , 1986, Annals of the New York Academy of Sciences.
[89] Yuichi Kanaoka,et al. Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence , 1984, Nature.
[90] M. Lazdunski,et al. Characterization, solubilization, affinity labeling and purification of the cardiac Na+ channel using Tityus toxin gamma. , 1984, European journal of biochemistry.
[91] W. Catterall,et al. The molecular basis of neuronal excitability. , 1984, Science.
[92] R. Campbell,et al. Antiarrhythmic drugs , 1995, Springer Berlin Heidelberg.
[93] B. Hille. Ionic selectivity, saturation, and block in sodium channels. A four- barrier model , 1975, The Journal of general physiology.
[94] B. Hille. The receptor for tetrodotoxin and saxitoxin. A structural hypothesis. , 1975, Biophysical journal.
[95] F. Bezanilla,et al. Currents Related to Movement of the Gating Particles of the Sodium Channels , 1973, Nature.
[96] B. Hille. The Permeability of the Sodium Channel to Metal Cations in Myelinated Nerve , 1972, The Journal of general physiology.
[97] B. Hille. The Permeability of the Sodium Channel to Organic Cations in Myelinated Nerve , 1971, The Journal of general physiology.