Sp7/Osterix Is Restricted to Bone-Forming Vertebrates where It Acts as a Dlx Co-factor in Osteoblast Specification.

[1]  J. Pike,et al.  Selective regulation of Mmp13 by 1,25(OH)2D3, PTH, and Osterix through distal enhancers , 2016, The Journal of Steroid Biochemistry and Molecular Biology.

[2]  Martha L. Bulyk,et al.  UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein–DNA interactions , 2014, Nucleic Acids Res..

[3]  H. Yoshioka,et al.  Sp7/Osterix induces the mouse pro-α2(I) collagen gene (Col1a2) expression via the proximal promoter in osteoblastic cells. , 2014, Biochemical and biophysical research communications.

[4]  H. Komori,et al.  Dlx5 and Mef2 Regulate a Novel Runx2 Enhancer for Osteoblast‐Specific Expression , 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[5]  C. Ureña,et al.  Mitogen-activated Protein Kinase (MAPK)-regulated Interactions between Osterix and Runx2 Are Critical for the Transcriptional Osteogenic Program* , 2014, The Journal of Biological Chemistry.

[6]  Brian J. Raney,et al.  Elephant shark genome provides unique insights into gnathostome evolution , 2014, Nature.

[7]  H. Deng,et al.  Pluripotent Stem Cells Induced from Mouse Somatic Cells by Small-Molecule Compounds , 2013, Science.

[8]  R. St-Arnaud,et al.  Control of Fiat (factor inhibiting ATF4‐mediated transcription) expression by Sp family transcription factors in osteoblasts , 2013, Journal of cellular biochemistry.

[9]  S. Kuraku,et al.  The Dlx genes as clues to vertebrate genomics and craniofacial evolution. , 2013, Seminars in cell & developmental biology.

[10]  Edgar Wingender,et al.  TFClass: an expandable hierarchical classification of human transcription factors , 2012, Nucleic Acids Res..

[11]  Alexander van Oudenaarden,et al.  Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. , 2012, Genes & development.

[12]  Chi Zhang,et al.  Matrix Metalloproteinase 13 (MMP13) Is a Direct Target of Osteoblast-Specific Transcription Factor Osterix (Osx) in Osteoblasts , 2012, PloS one.

[13]  William Stafford Noble,et al.  Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors , 2012, Genome research.

[14]  S. Fisher,et al.  Evolution of the bone gene regulatory network. , 2012, Current opinion in genetics & development.

[15]  B. de Crombrugghe,et al.  Characterization of Dkk1 gene regulation by the osteoblast-specific transcription factor Osx. , 2012, Biochemical and biophysical research communications.

[16]  Fanxin Long,et al.  Building strong bones: molecular regulation of the osteoblast lineage , 2011, Nature Reviews Molecular Cell Biology.

[17]  Hongli Jiao,et al.  Transcriptional Regulation of Vascular Endothelial Growth Factor (VEGF) by Osteoblast-specific Transcription Factor Osterix (Osx) in Osteoblasts , 2011, Journal of Biological Chemistry.

[18]  Timothy L. Bailey,et al.  Gene expression Advance Access publication May 4, 2011 DREME: motif discovery in transcription factor ChIP-seq data , 2011 .

[19]  J. DeWoody,et al.  Evolutionary rates of mitochondrial genomes correspond to diversification rates and to contemporary species richness in birds and reptiles , 2010, Proceedings of the Royal Society B: Biological Sciences.

[20]  H. Yoshioka,et al.  Sp7/Osterix is involved in the up-regulation of the mouse pro-α1(V) collagen gene (Col5a1) in osteoblastic cells. , 2010, Matrix biology : journal of the International Society for Matrix Biology.

[21]  P. Lapunzina,et al.  Identification of a frameshift mutation in Osterix in a patient with recessive osteogenesis imperfecta. , 2010, American journal of human genetics.

[22]  Jian Q. Feng,et al.  Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice , 2010, Proceedings of the National Academy of Sciences.

[23]  Cory Y. McLean,et al.  GREAT improves functional interpretation of cis-regulatory regions , 2010, Nature Biotechnology.

[24]  H. Yoshioka,et al.  Sp7/Osterix up-regulates the mouse pro-alpha3(V) collagen gene (Col5a3) during the osteoblast differentiation. , 2010, Biochemical and biophysical research communications.

[25]  Ernest Fraenkel,et al.  Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis. , 2009, Molecular cell.

[26]  D. Larhammar,et al.  Evolution of vertebrate rod and cone phototransduction genes , 2009, Philosophical Transactions of the Royal Society B: Biological Sciences.

[27]  Cole Trapnell,et al.  Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.

[28]  G. Karsenty.  Transcriptional control of skeletogenesis. , 2008, Annual review of genomics and human genetics.

[29]  Ji Hyun Kim,et al.  Activation of PPARgamma negatively regulates O-GlcNAcylation of Sp1. , 2008, Biochemical and biophysical research communications.

[30]  Daniel E. Newburger,et al.  Variation in Homeodomain DNA Binding Revealed by High-Resolution Analysis of Sequence Preferences , 2008, Cell.

[31]  Haitao Li,et al.  Expression and function of Dlx genes in the osteoblast lineage. , 2008, Developmental biology.

[32]  A. McMahon,et al.  Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors , 2006, Development.

[33]  T. Kodama,et al.  NFAT and Osterix cooperatively regulate bone formation , 2005, Nature Medicine.

[34]  J. Stains,et al.  Genomic approaches to identifying transcriptional regulators of osteoblast differentiation , 2003, Genome Biology.

[35]  T. Lufkin,et al.  The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. , 2002, Genes & development.

[36]  J. Deng,et al.  The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation , 2002, Cell.

[37]  H. Shibuya,et al.  Dlxin-1, a Novel Protein That Binds Dlx5 and Regulates Its Transcriptional Function* , 2001, The Journal of Biological Chemistry.

[38]  B. Olsen,et al.  Bone development. , 2000, Annual review of cell and developmental biology.

[39]  G. Suske.  The Sp-family of transcription factors. , 1999, Gene.

[40]  M. Owen,et al.  Mutations Involving the Transcription Factor CBFA1 Cause Cleidocranial Dysplasia , 1997, Cell.

[41]  Makoto Sato,et al.  Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts , 1997, Cell.

[42]  D. Rowe,et al.  Regulation of COL1A1 expression in type I collagen producing tissues: Identification of a 49 base pair region which is required for transgene expression in bone of transgenic mice , 1995, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[43]  V. Rosen,et al.  The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2. , 1990, Biochemical and biophysical research communications.

[44]  Robert Tjian,et al.  Promoter-specific activation of RNA polymerase II transcription by Sp1 , 1986 .