A household LOC device for online monitoring bacterial pathogens in drinking water with green design concept

Bacterial waterborne pathogens often threaten the water safety of the drinking water system. In order to protect the health of home users, a household lab-on-a-chip (LOC) device was developed for online monitoring bacterial pathogens in drinking water, which are in accord with green design concept. The chip integrated counter-flow micromixers, a T-junction droplet generator and time-delay channels (TD-Cs), which can mix water sample and reactants into droplets in air flow and incubate the droplets in the LOC for about 18 hours before observation. The detection module was simplified into a transparent observation chamber, from which the home users can evaluate the qualitative result by naked eyes. The liquid waste generated by the LOC system was sterilized and absorbed by quicklime powders. No secondary pollution was found. The preliminary test of the prototype system met its design requirements.

[1]  Tao Dong,et al.  Integrated micro Pirani gauge based hermetical package monitoring for uncooled VOx bolometer FPAs , 2011 .

[2]  Zhaochu Yang,et al.  Molecular simulations of R141b boiling flow in micro/nano channel: Interfacial phenomena , 2006 .

[3]  Eirik Bentzen Egeland,et al.  Integratable non-clogging microconcentrator based on counter-flow principle for continuous enrichment of CaSki cells sample , 2011 .

[4]  Jeong-Yeol Yoon,et al.  Lab-on-a-Chip Pathogen Sensors for Food Safety , 2012, Sensors.

[5]  J. G. E. Gardeniers,et al.  Lab-On-A-Chip Systems For Biomedical And Environmental Monitoring , 2003, Int. J. Comput. Eng. Sci..

[6]  Christopher W. Wong,et al.  Pathogen Chip for Respiratory Tract Infections , 2013, Journal of Clinical Microbiology.

[7]  Tao Dong,et al.  A smart fully integrated micromachined separator with soft magnetic micro-pillar arrays for cell isolation , 2010 .

[8]  Zhaochu Yang,et al.  Compatible immuno-NASBA LOC device for quantitative detection of waterborne pathogens: design and validation. , 2012, Lab on a chip.

[9]  Tao Dong,et al.  Power generation from conductive droplet sliding on electret film , 2012 .

[10]  Yibin Ying,et al.  New Trends in Impedimetric Biosensors for the Detection of Foodborne Pathogenic Bacteria , 2012, Sensors.

[11]  Tao Dong,et al.  Design and optimization of non-clogging counter-flow microconcentrator for enriching epidermoid cervical carcinoma cells , 2011, Biomedical microdevices.

[12]  Tao Dong,et al.  Measurement and modeling of R141b condensation heat transfer in silicon rectangular microchannels , 2008 .

[13]  Thomas Henkel,et al.  Generation of larger numbers of separated microbial populations by cultivation in segmented-flow microdevices. , 2003, Lab on a chip.

[14]  Tao Dong,et al.  Measurement and analysis of Vibrio Fischeri cell-based microfluidic device for personal health monitoring , 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[15]  J. Karns,et al.  A handheld real time thermal cycler for bacterial pathogen detection. , 2003, Biosensors & bioelectronics.