A low-power receiver for simultaneous electrocardiogram and respiration rate detection

This paper presents an integrated low-power analog front end (AFE) for simultaneously detecting electrocardiogram (ECG) and respiration rate (RR). A low-power low-noise preamplifier is designed to amplify both the ECG and RR signals. A current-driven passive mixer is used in the RR path to up-convert the RR signal so that the ECG signal can be filtered out. The modulated RR signal is then down-converted to baseband to be further amplified and detected. Quadrature (I and Q) drive signals for the mixers are generated on-chip from an external 20 kHz clock signal. The receiver is fabricated on the OnSemi 0.5 μm CMOS process. Both simulation and preliminary measurement results verify the functionality of this work. The overall gain for the ECG and RR signals are 40 dB and 70 dB respectively, and the circuit draws 6.2 μA from a 3 V power supply. To the best of the authors' knowledge, this is the first work in the literature that shows integrated RR and ECG signal detection with such low power consumption.

[1]  Mark D. Huffman,et al.  AHA Statistical Update Heart Disease and Stroke Statistics — 2012 Update A Report From the American Heart Association WRITING GROUP MEMBERS , 2010 .

[2]  Jari Hyttinen,et al.  Assessment of Pulmonary Flow Using Impedance Pneumography , 2010, IEEE Transactions on Biomedical Engineering.

[3]  Rahul Sarpeshkar,et al.  Ultralow-Power Electronics for Cardiac Monitoring , 2010, IEEE Transactions on Circuits and Systems I: Regular Papers.

[4]  Michael Norris,et al.  Design and development of medical electronic instrumentation : a practical perspective of the design, construction, and test of medical devices , 2004 .

[5]  Rahul Sarpeshkar,et al.  A Low-Power Wide-Linear-Range Transconductance Amplifier , 1997 .

[6]  Tobi Delbrück,et al.  Adaptive photoreceptor with wide dynamic range , 1994, Proceedings of IEEE International Symposium on Circuits and Systems - ISCAS '94.

[7]  B. Hök,et al.  Critical review of non-invasive respiratory monitoring in medical care , 2003, Medical and Biological Engineering and Computing.

[8]  Rahul Sarpeshkar,et al.  A Micropower Electrocardiogram Amplifier , 2009, IEEE Transactions on Biomedical Circuits and Systems.

[9]  Amendment of recommendations for standardization of specifications for instruments in electrocardiography and vectorcardiography concerning safety and electrical shock hazards. , 1973, IEEE transactions on bio-medical engineering.

[10]  Li Bin,et al.  A system of portable ECG monitoring based on Bluetooth mobile phone , 2011, 2011 IEEE International Symposium on IT in Medicine and Education.

[11]  W. L. Cooley,et al.  Impedance pneumography. Comparison between chest impedance changes and respiratory volumines in 11 healthy volunteers. , 1972, Chest.

[12]  Ye Li,et al.  A full custom analog front-end for long-time ECG monitoring , 2013, Annual International Conference of the IEEE Engineering in Medicine and Biology Society.