Breastfeeding and Breast Milk Jaundice

TWO TYPES of jaundice associated with breast feeding are recognized. The first type is early onset breastfeeding jaundice which may result from caloric deprivation and/or insufficient frequency of feeding. This type of jaundice can be prevented or treated by encouraging mothers to nurse as frequently as possible, particularly if the bilirubin level is rising. The second type is later onset, prolonged jaundice, known as the breast milk jaundice syndrome which is associated with one or more abnormalities in the maternal milk itself. Breast milk jaundice syndrome generally needs no therapy if serum bilirubin concen trations remain below 270 μmol/l in healthy full-term infants. When the serum bilirubin concentration is above 270 μmol/l and rising, temporary interruption of breastfeeding may be indicated.

[1]  M. Nussinovitch,et al.  Breast Milk Jaundice in Preterm infants , 1988, Clinical pediatrics.

[2]  L. Gartner,et al.  Breast milk and breastfeeding jaundice. , 1987, Advances in pediatrics.

[3]  M. J. Maisels,et al.  Normal serum bilirubin levels in the newborn and the effect of breast-feeding. , 1986, Pediatrics.

[4]  A. Schneider Breast milk jaundice in the newborn. A real entity. , 1986, JAMA.

[5]  A. Singh,et al.  Dr. Singh and associates reply. , 1986 .

[6]  G. Gourley,et al.  β-GLUCURONIDASE AND HYPERBILIRUBINAEMIA IN BREAST-FED AND FORMULA-FED BABIES , 1986, The Lancet.

[7]  A. Lascari "Early" breast-feeding jaundice: clinical significance. , 1986, The Journal of pediatrics.

[8]  M. Klaus,et al.  Fecal bilirubin excretion and serum bilirubin concentrations in breast-fed and bottle-fed infants. , 1985, The Journal of pediatrics.

[9]  T. Nikkari,et al.  Neonatal Jaundice and Fatty Acid Composition of the Maternal Diet , 1985, Acta paediatrica Scandinavica.

[10]  B. Nichols,et al.  Free fatty acids in the development of breast milk jaundice. , 1985, Journal of pediatric gastroenterology and nutrition.

[11]  L. Osborn,et al.  Breast feeding and jaundice in the first week of life. , 1985, The Journal of family practice.

[12]  B. Rosner,et al.  Epidemiology of neonatal hyperbilirubinemia. , 1985, Pediatrics.

[13]  N. B. White,et al.  Metabolic aspects of phototherapy. , 1985, Pediatrics.

[14]  Joyce A. Adams,et al.  Incidence of Hyperbilirubinemia in Breast- vs. Formula-fed Infants , 1985, Clinical pediatrics.

[15]  G. Herbison,et al.  Jaundice in full term healthy neonates — a population study , 1984, Australian paediatric journal.

[16]  C. Kivlahan,et al.  The natural history of neonatal jaundice. , 1984, Pediatrics.

[17]  M. J. Maisels,et al.  Neonatal jaundice in full-term infants. Role of breast-feeding and other causes. , 1983, American journal of diseases of children.

[18]  D. A. Butler,et al.  Relationship of breast feeding and weight loss to jaundice in the newborn period: review of the literature and results of a study. , 1983, Cleveland Clinic quarterly.

[19]  N. Paneth,et al.  Feeding Practices and Early Neonatal Jaundice , 1982, Journal of pediatric gastroenterology and nutrition.

[20]  S. Saigal,et al.  Serum bilirubin levels in breast- and formula-fed infants in the first 5 days of life. , 1982, Canadian Medical Association journal.

[21]  J. Tripp,et al.  SUPPLEMENTARY FEEDING AND JAUNDICE IN NEWBORNS , 1982, Acta paediatrica Scandinavica.

[22]  O. Hernell Breast-milk jaundice. , 1982, The Journal of pediatrics.

[23]  M. Klaus,et al.  Frequency of breast-feeding and serum bilirubin concentration. , 1982, American journal of diseases of children.

[24]  I. Hughes,et al.  Pregnanediols and breast milk jaundice. , 1981, Archives of disease in childhood.

[25]  D. Stevenson,et al.  Pulmonary excretion of carbon monoxide in the human infant as an index of bilirubin production. IV. Effects of breast-feeding and caloric intake in the first postnatal week. , 1980, Pediatrics.

[26]  Brown Ak,et al.  Phototherapy for neonatal hyperbilirubinemia: efficacy, mechanism and toxicity. , 1980, Advances in pediatrics.

[27]  L. Gartner,et al.  Effect of starvation and milk feeding on intestinal bilirubin absorption. , 1980 .

[28]  J. Waterhouse,et al.  Are breast-fed babies still getting a raw deal in hospital? , 1979, British medical journal.

[29]  R. A. Rubin,et al.  Neonatal serum bilirubin levels related to cognitive development at ages 4 through 7 years. , 1979, The Journal of pediatrics.

[30]  John D. Johnson,et al.  Pulmonary excretion of carbon monoxide in the human infant as an index of bilirubin production , 1979, The Journal of pediatrics.

[31]  L. Curda,et al.  Jaundice and breast-feeding among Alaskan Eskimo newborns. , 1978, American journal of diseases of children.

[32]  P. Scheidt,et al.  Toxicity to bilirubin in neonates: infant development during first year in relation to maximum neonatal serum bilirubin concentration. , 1977, The Journal of pediatrics.

[33]  M. Odiévre,et al.  Breast Milk Jaundice: In Vitro Inhibition of Rat Liver Bilirubin-Uridine Diphosphate Glucuronyltransferase Activity and Z Protein-Bromosulfophthalein Binding by Human Breast Milk , 1976, Pediatric Research.

[34]  G. H. Lathe Neonatal bilirubin metabolism in relation to jaundice. , 1976, Clinics in endocrinology and metabolism.

[35]  H. Fleming Letter: Prophylaxis of bacterial endocarditis. , 1976, Lancet.

[36]  A. P. Norman,et al.  Increased frequency of neonatal jaundice in a maternity hospital. , 1975, British medical journal.

[37]  M. Odièvre,et al.  Activite de la lipoproteine lipase dans les laits de femme inhibiteurs in vitro de la conjugaison de la bilirubine , 1975 .

[38]  M. Cohen,et al.  Navajo jaundice: a variant of neonatal hyperbilirubinemia associated with breast feeding. , 1974, The Journal of pediatrics.

[39]  M. Odiévre,et al.  Demonstration of a lipolytic activity in human milk that inhibits the glucuro-conjugation of bilirubin. , 1974, Biomedicine / [publiee pour l'A.A.I.C.I.G.].

[40]  P. Auld,et al.  Breast feeding and serum bilirubin values during the first 4 days of life. , 1973, The Journal of pediatrics.

[41]  T. Hargreaves Effect of fatty acids on bilirubin conjugation , 1973, Archives of disease in childhood.

[42]  J. Holton,et al.  Inhibition of bilirubin conjugation in rat liver slices by free fatty acids, with relevance to the problem of breast milk jaundice. , 1972, Clinica chimica acta; international journal of clinical chemistry.

[43]  Y. Wong,et al.  Breast-milk jaundice and the pill. , 1972, British medical journal.

[44]  Y. Wong,et al.  Breast-milk Jaundice and Oral Contraceptives , 1971, British medical journal.

[45]  F. Rodkey,et al.  Studies on the mechanism of fasting hyperbilirubinemia. , 1971, Gastroenterology.

[46]  R. Poland,et al.  Physiologic jaundice: the enterohepatic circulation of bilirubin. , 1971, The New England journal of medicine.

[47]  M. Takimoto,et al.  -glucruonidase activity in the stool of the newborn infant. , 1971, Biology of the neonate.

[48]  J. Waterhouse,et al.  Sequelae of neonatal jaundice. , 1970, British medical journal.

[49]  G. H. Lathe,et al.  Breast Milk Jaundice: Effect of 3α 20β-pregnanediol on Bilirubin Conjugation by Human Liver , 1970 .

[50]  G. H. Lathe,et al.  Breast milk jaundice: effect of 3-alpha 20-beta-pregnanediol on bilirubin conjugation by human liver. , 1970, Archives of disease in childhood.

[51]  J. Rosta,et al.  Delayed meconium passage and hyperbilirubinaemia. , 1968, Lancet.

[52]  L. Stern,et al.  Pregnanediols and neonatal hyperbilirubinemia. , 1966, American journal of diseases of children.

[53]  H. Bishop,et al.  NEONATAL HYPERBILIRUBINEMIA ASSOCIATED WITH HIGH OBSTRUCTION OF THE SMALL BOWEL. , 1965, The Journal of pediatrics.

[54]  I. Arias,et al.  Production of unconjugated hyperbilirubinemia in full-term newborn infants following administration of pregnane-3(alpha), 20(beta)-diol , 1964 .

[55]  S. Seifter,et al.  PROLONGED NEONATAL UNCONJUGATED HYPERBILIRUBINEMIA ASSOCIATED WITH BREAST FEEDING AND A STEROID, PREGNANE-3(ALPHA), 20(BETA)-DIOL, IN MATERNAL MILK THAT INHIBITS GLUCURONIDE FORMATION IN VITRO. , 1964, The Journal of clinical investigation.

[56]  L. Gartner,et al.  Production of Unconjugated Hyperbilirubinæmia in Full-term New-born Infants following Administration of Pregnane-3(alpha), 20(beta)-diol , 1964, Nature.

[57]  G. Fashena Mechanism of hyperbilirubinemia in the newborn infant; experimental demonstration of functional hepatic immaturity. , 1948, American journal of diseases of children.

[58]  F. T. Frerichs A Clinical Treatise on Diseases of the Liver , 1859, The British and foreign medico-chirurgical review.