Comprehensive DNA methylation analysis of tissue of origin of plasma cell-free DNA by methylated CpG tandem amplification and sequencing (MCTA-Seq)

[1]  Endre Kiss,et al.  Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease , 2018, Nature Communications.

[2]  Peiyong Jiang,et al.  Liver- and Colon-Specific DNA Methylation Markers in Plasma for Investigation of Colorectal Cancers with or without Liver Metastases. , 2018, Clinical chemistry.

[3]  Y. Dor,et al.  Monitoring liver damage using hepatocyte-specific methylation markers in cell-free circulating DNA. , 2018, JCI insight.

[4]  C. Enerbäck,et al.  Genome-Wide DNA Methylation Profiling Identifies Differential Methylation in Uninvolved Psoriatic Epidermis. , 2017, The Journal of investigative dermatology.

[5]  Peiyong Jiang,et al.  DNA of Erythroid Origin Is Present in Human Plasma and Informs the Types of Anemia. , 2017, Clinical chemistry.

[6]  E. Li,et al.  DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease , 2017, Proceedings of the National Academy of Sciences.

[7]  Lianghong Zheng,et al.  DNA methylation markers for diagnosis and prognosis of common cancers , 2017, Proceedings of the National Academy of Sciences.

[8]  James D. Brenton,et al.  Liquid biopsies come of age: towards implementation of circulating tumour DNA , 2017, Nature Reviews Cancer.

[9]  Fengzhu Sun,et al.  CancerLocator: non-invasive cancer diagnosis and tissue-of-origin prediction using methylation profiles of cell-free DNA , 2017, Genome Biology.

[10]  L. Pączek,et al.  The role and diagnostic value of cell-free DNA in systemic lupus erythematosus. , 2017, Clinical and experimental rheumatology.

[11]  Kang Zhang,et al.  Identification of methylation haplotype blocks aids in deconvolution of heterogeneous tissue samples and tumor tissue-of-origin mapping from plasma DNA , 2017, Nature Genetics.

[12]  R. Tothill,et al.  Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis. , 2016, The Lancet. Oncology.

[13]  Henrik Zetterberg,et al.  Identification of tissue-specific cell death using methylation patterns of circulating DNA , 2016, Proceedings of the National Academy of Sciences.

[14]  Y. Lo,et al.  Prenatal Diagnosis Innovation: Genome Sequencing of Maternal Plasma. , 2016, Annual review of medicine.

[15]  F. Tang,et al.  Genome-scale detection of hypermethylated CpG islands in circulating cell-free DNA of hepatocellular carcinoma patients , 2015, Cell Research.

[16]  E. Ma,et al.  Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments , 2015, Proceedings of the National Academy of Sciences.

[17]  T. Boyer,et al.  Big spleens and hypersplenism: fix it or forget it? , 2015, Liver international : official journal of the International Association for the Study of the Liver.

[18]  Michael Q. Zhang,et al.  Integrative analysis of 111 reference human epigenomes , 2015, Nature.

[19]  D. Schübeler.  Function and information content of DNA methylation , 2015, Nature.

[20]  B. Vogelstein,et al.  Variation in cancer risk among tissues can be explained by the number of stem cell divisions , 2015, Science.

[21]  M. Giacca,et al.  Exercise-induced increases in cell free DNA in human plasma originate predominantly from cells of the haematopoietic lineage. , 2015, Exercise immunology review.

[22]  G. Lippi,et al.  Cell-free DNA for diagnosing myocardial infarction: not ready for prime time , 2015, Clinical chemistry and laboratory medicine.

[23]  G. Creatsas,et al.  DNA sequencing versus standard prenatal aneuploidy screening. , 2014, The New England journal of medicine.

[24]  Kang Zhang,et al.  DNA sequencing versus standard prenatal aneuploidy screening. , 2014, The New England journal of medicine.

[25]  Raffaella Casadei,et al.  An estimation of the number of cells in the human body , 2013, Annals of human biology.

[26]  A. Gnirke,et al.  Charting a dynamic DNA methylation landscape of the human genome , 2013, Nature.

[27]  P. Jiang,et al.  High-resolution profiling of fetal DNA clearance from maternal plasma by massively parallel sequencing. , 2013, Clinical chemistry.

[28]  P. Simon,et al.  Circulating Cell-Free DNA , 2012, Sports Medicine.

[29]  M. Esteller,et al.  DNA methylation profiling in the clinic: applications and challenges , 2012, Nature Reviews Genetics.

[30]  D. Cook,et al.  Prognostic utility and characterization of cell-free DNA in patients with severe sepsis , 2012, Critical Care.

[31]  Thomas Lengauer,et al.  A DNA methylation fingerprint of 1628 human samples. , 2011, Genome research.

[32]  Yanjun Zeng,et al.  Quantitation of Plasma Circulating DNA Using Quantitative PCR for the Detection of Hepatocellular Carcinoma , 2012, Pathology & Oncology Research.

[33]  P. Lizardi,et al.  Detection of β cell death in diabetes using differentially methylated circulating DNA , 2011, Proceedings of the National Academy of Sciences.

[34]  S. Rafii,et al.  Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. , 2011, Molecular cell.

[35]  Klaus Pantel,et al.  Cell-free nucleic acids as biomarkers in cancer patients , 2011, Nature Reviews Cancer.

[36]  Yixin Yin,et al.  A Hybrid of Particle Swarm Optimization and Local Search for Multimodal Functions , 2010, ICSI.

[37]  G. Lauc,et al.  Free serum DNA is an early predictor of severity in acute pancreatitis. , 2009, Clinical biochemistry.

[38]  Jim Stalker,et al.  A Novel CpG Island Set Identifies Tissue-Specific Methylation at Developmental Gene Loci , 2008, PLoS biology.

[39]  N. Iizuka,et al.  Circulating cell-free DNA as a predictive marker for distant metastasis of hepatitis C virus-related hepatocellular carcinoma , 2007, British Journal of Cancer.

[40]  L. Qin,et al.  The prognostic value of circulating plasma DNA level and its allelic imbalance on chromosome 8p in patients with hepatocellular carcinoma , 2006, Journal of Cancer Research and Clinical Oncology.

[41]  Frank Diehl,et al.  Detection and quantification of mutations in the plasma of patients with colorectal tumors. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[42]  Doron Lancet,et al.  Genome-wide midrange transcription profiles reveal expression level relationships in human tissue specification , 2005, Bioinform..

[43]  W. Burdick.  Detecting acute coronary syndrome in the emergency department with cardiac magnetic resonance imaging , 2004 .

[44]  Michael N. Vrahatis,et al.  Recent approaches to global optimization problems through Particle Swarm Optimization , 2002, Natural Computing.

[45]  A. Levin,et al.  Tissue disposition of 2'-O-(2-methoxy) ethyl modified antisense oligonucleotides in monkeys. , 2004, Journal of pharmaceutical sciences.

[46]  A. Burroughs,et al.  Hepatocellular carcinoma , 2003, The Lancet.

[47]  Y. Lo,et al.  Time course of early and late changes in plasma DNA in trauma patients. , 2003, Clinical chemistry.

[48]  Y. Lo,et al.  Prognostic use of circulating plasma nucleic acid concentrations in patients with acute stroke. , 2003, Clinical chemistry.

[49]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[50]  D. Woodfield.  Hepatocellular carcinoma. , 1986, The New Zealand medical journal.

[51]  B. Shapiro,et al.  Determination of circulating DNA levels in patients with benign or malignant gastrointestinal disease , 1983, Cancer.

[52]  B. Shapiro,et al.  Free DNA in the serum of cancer patients and the effect of therapy. , 1977, Cancer research.