Assessment of urinary β‐core fragment of human chorionic gonadotropin as a new tumor marker of lung cancer

Background. Some patients with lung cancer have been found to have elevated levels of serum immunore‐active human chorionic gonadotropin (hCG)/hCGß (IR‐β), but it is uncertain whether it would be valuable as a tumor marker. Recently, IR‐β has been demonstrated to consist of at least three different molecules, intact hCG, free hCGβ, and hCGβ‐core fragment (β‐CF), in body fluids. In this study, the authors qualitatively analyzed IR‐β in the serum and urine of patients with lung cancer and assessed its clinical usefulness as a tumor marker.

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