Design of an Intervention to Minimize Ingestion of Fecal Microbes by Young Children in Rural Zimbabwe

We sought to develop a water, sanitation, and hygiene (WASH) intervention to minimize fecal–oral transmission among children aged 0–18 months in the Sanitation Hygiene Infant Nutrition Efficacy (SHINE) trial. We undertook 4 phases of formative research, comprising in-depth interviews, focus group discussions, behavior trials, and a combination of observations and microbiological sampling methods. The resulting WASH intervention comprises material inputs and behavior change communication to promote stool disposal, handwashing with soap, water treatment, protected exploratory play, and hygienic infant feeding. Nurture and disgust were found to be key motivators, and are used as emotional triggers. The concept of a safe play space for young children was particularly novel, and families were eager to implement this after learning about the risks of unprotected exploratory play. An iterative process of formative research was essential to create a sequenced and integrated longitudinal intervention for a SHINE household as it expects (during pregnancy) and then cares for a new child.

[1]  M. Becker,et al.  The Health Belief Model: A Decade Later , 1984, Health education quarterly.

[2]  H. Bernard Research Methods in Anthropology: Qualitative and Quantitative Approaches , 1988 .

[3]  S. Laver,et al.  Community mortality from cholera: urban and rural districts in Zimbabwe. , 2013, The American journal of tropical medicine and hygiene.

[4]  R. Stevenson,et al.  Can the emotion of disgust be harnessed to promote hand hygiene? Experimental and field-based tests. , 2009, Social science & medicine.

[5]  J. Tangney,et al.  On the importance of distinguishing shame from guilt: relations to problematic alcohol and drug use. , 2005, Addictive behaviors.

[6]  Jean H Humphrey,et al.  Child undernutrition, tropical enteropathy, toilets, and handwashing , 2009, The Lancet.

[7]  R. Stoltzfus,et al.  Water, sanitation, and hygiene (WASH), environmental enteropathy, nutrition, and early child development: making the links , 2014, Annals of the New York Academy of Sciences.

[8]  Robert Aunger,et al.  Effect of a behaviour-change intervention on handwashing with soap in India (SuperAmma): a cluster-randomised trial. , 2014, The Lancet. Global health.

[9]  R. Aunger,et al.  Marketing hygiene behaviours: the impact of different communication channels on reported handwashing behaviour of women in Ghana. , 2008, Health education research.

[10]  W. Neuman,et al.  Social Research Methods: Qualitative and Quantitative Approaches , 2002 .

[11]  A. Manges,et al.  The Sanitation Hygiene Infant Nutrition Efficacy (SHINE) Trial: Rationale, Design, and Methods , 2015, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[12]  R. Gilman,et al.  Fecal contamination of shanty town toddlers in households with non-corralled poultry, Lima, Peru. , 1990, American journal of public health.

[13]  S. Cousens,et al.  Dirt and diarrhoea: formative research in hygiene promotion programmes. , 1997, Health policy and planning.

[14]  R. Stoltzfus,et al.  Formative Research on Hygiene Behaviors and Geophagy among Infants and Young Children and Implications of Exposure to Fecal Bacteria , 2013, The American journal of tropical medicine and hygiene.

[15]  G. Root Sanitation, community environments, and childhood diarrhoea in rural Zimbabwe. , 2001, Journal of health, population, and nutrition.

[16]  Joseph N S Eisenberg,et al.  Integrating disease control strategies: balancing water sanitation and hygiene interventions to reduce diarrheal disease burden. , 2007, American journal of public health.

[17]  J. Lucks,et al.  Why On Earth?: Evaluating Hypotheses About The Physiological Functions Of Human Geophagy , 2011, The Quarterly Review of Biology.

[18]  Sandy Cairncross,et al.  Review: Domestic hygiene and diarrhoea – pinpointing the problem , 2000 .

[19]  S. Cairncross,et al.  Domestic hygiene and diarrhoea - pinpointing the problem. , 2000, Tropical medicine & international health : TM & IH.

[20]  V. Curtis,et al.  Health in our hands, but not in our heads: understanding hygiene motivation in Ghana. , 2007, Health policy and planning.

[21]  M. Elia,et al.  Growth faltering in rural Gambian infants is associated with impaired small intestinal barrier function, leading to endotoxemia and systemic inflammation. , 2003, The Journal of nutrition.

[22]  S. Flocke,et al.  Teachable moments for health behavior change: a concept analysis. , 2009, Patient Education and Counseling.

[23]  R. Haque,et al.  Geophagy is associated with environmental enteropathy and stunting in children in rural Bangladesh. , 2015, The American journal of tropical medicine and hygiene.

[24]  K. Schwab,et al.  Using Geographic Information Systems and Spatial Analysis Methods to Assess Household Water Access and Sanitation Coverage in the SHINE Trial , 2015, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[25]  L. Moulton,et al.  Theory-Driven Process Evaluation of the SHINE Trial Using a Program Impact Pathway Approach , 2015, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[26]  E. G. Wagner,et al.  Excreta Disposal for Rural Areas and Small Communities , 1959, Monograph series. World Health Organization.

[27]  R. Aunger,et al.  Planned, motivated and habitual hygiene behaviour: an eleven country review , 2009, Health education research.

[28]  M. Mazariegos,et al.  The underprivileged, developing country child: environmental contamination and growth failure revisited. , 2009, Nutrition reviews.

[29]  J. Tangney,et al.  Moral emotions and moral behavior. , 2007, Annual review of psychology.

[30]  Ruud Albers,et al.  Environmental enteropathy: new targets for nutritional interventions. , 2010, International health.

[31]  R. Haque,et al.  Household Environmental Conditions Are Associated with Enteropathy and Impaired Growth in Rural Bangladesh , 2013, The American journal of tropical medicine and hygiene.

[32]  P. Lunn,et al.  The impact of infection and nutrition on gut function and growth in childhood , 2000, Proceedings of the Nutrition Society.

[33]  P. Milla,et al.  Chronic diarrhea and malnutrition--histology of the small intestinal lesion. , 1991, Journal of Pediatric Gastroenterology and Nutrition - JPGN.

[34]  Twice Humanity: Implications for Local and Global Resource Use , 1998 .

[35]  M. Knowles The Modern Practice of Adult Education: From Pedagogy to Andragogy , 1970 .

[36]  I. Rosenberg,et al.  Implications of Acquired Environmental Enteric Dysfunction for Growth and Stunting in Infants and Children Living in Low- and Middle-Income Countries , 2013, Food and nutrition bulletin.

[37]  P. Lunn,et al.  Pathways leading to early growth faltering: an investigation into the importance of mucosal damage and immunostimulation in different socio-economic groups in Nepal , 2008, British Journal of Nutrition.