Application of a new triple sequential embolization method in treatment of hepatic hemangioma

Background: The treatment of hepatic hemangiomas by current methods has limitations such as various complications, so more effective methods are needed. Objective: The objective of the present investigation was to explore the effect of sequential application of new triple microsphere method on super selective embolization of capillary and small arteries of the patients with hepatic hemangioma. Materials and methods: A novel triple sequential embolization material was prepared. Totally, 68 patients with hepatic hemangioma were divided into triple sequential embolization method group and iodipin embolization group. The demographics, clinical characteristics, diagnosis, surgery, complications and treatment outcomes were analyzed. Results: The treatment effects of the new triple sequential embolization methods were significantly better than that of the single application of iodipin embolization, of which there were 8 cases with markedly effective treatment effects, 26 cases with valid effects and 6 cases without valid effects. The sizes of tumors were examined in reexamination by CT. Furthermore, the numbers and types of side effects in the triple sequential embolization method group were less than those in the iodipin embolization group. Conclusion: A novel triple sequential embolization material was prepared successfully. Treatment of interventional embolization with the material consisting of microspheres and iodipin in hepatic hemangioma is economic, safe, effective and minimally invasive, and surgical operation can be avoided after interventional embolization treatment in most patients with hepatic hemangioma.

[1]  Tao Wang,et al.  Efficacy, safety and feasibility of ultrasound‐guided percutaneous microwave ablation for large hepatic hemangioma , 2015, Journal of digestive diseases.

[2]  P. Arora,et al.  Large Multifocal Cutaneous Hemangioma Along Lines of Blaschko with Cardiac Failure Treated with Propranolol , 2015, Pediatric dermatology.

[3]  I. Oran,et al.  Unusual treatment of Kasabach–Merritt syndrome secondary to hepatic hemangioma: embolization with bleomycin , 2015, Wiener klinische Wochenschrift.

[4]  Q. Shu,et al.  Imaging findings of multiple infantile hepatic hemangioma associated with cardiac insufficiency , 2014, World Journal of Pediatrics.

[5]  Xiao-Dong Sun,et al.  Sclerosing cholangitis secondary to bleomycin-iodinated embolization for liver hemangioma. , 2014, World journal of gastroenterology.

[6]  B. Wible,et al.  Ethylene-vinyl alcohol copolymer endobiliary obliteration of hepatic segments in a patient with isolated bile leaks. , 2014, Journal of vascular and interventional radiology : JVIR.

[7]  A. Ejaz,et al.  Surgical management of hepatic hemangiomas: a multi-institutional experience. , 2014, HPB : the official journal of the International Hepato Pancreato Biliary Association.

[8]  O. Abbasoğlu,et al.  Is surgical treatment of liver hemangiomas effective for pain relief? , 2014, Chirurgia.

[9]  S. Bouraoui,et al.  Primary hepatic vascular tumours. A clinicopathologic study of 10 cases. , 2014, Acta gastro-enterologica Belgica.

[10]  I. Adaletli,et al.  The impact of share wave elastography in differentiation of hepatic hemangioma from malignant liver tumors in pediatric population. , 2014, European journal of radiology.

[11]  J. Marrero,et al.  ACG Clinical Guideline: The Diagnosis and Management of Focal Liver Lesions , 2014, The American Journal of Gastroenterology.

[12]  R. Azizkhan,et al.  Hepatic vascular tumors. , 2014, Seminars in pediatric surgery.

[13]  I. Fernandez-Pineda,et al.  Differential diagnosis and management of liver tumors in infants. , 2014, World journal of hepatology.

[14]  M. Deng,et al.  Primary hepatic mucosa-associated lymphoid tissue lymphoma and hemangioma with chronic hepatitis B virus infection as an underlying condition. , 2014, Bioscience trends.

[15]  W. Lau,et al.  Selective Hepatic Vascular Exclusion versus Pringle Maneuver in Partial Hepatectomy for Liver Hemangioma Compressing or Involving the Major Hepatic Veins , 2014, The American surgeon.

[16]  J. de Ville de Goyet,et al.  Prehepatic portal hypertension with aneurysm of the portal vein: unusual but treatable malformative pattern. , 2014, Journal of pediatric surgery.

[17]  H. Ahmad,et al.  Multiple Cutaneous and Hepatic Hemangiomas in Infants , 2014, Southern medical journal.

[18]  M. Ercan,et al.  Giant hemangiomas: effects of size and type of surgical procedure on postoperative outcome. , 2014, Hepato-Gastroenterology.