Functionalized Lipid Particulates in Targeted Drug Delivery

Lipid particulates as the name suggests are a breed of novel delivery systems consisting of lipids or lipid based excipients as its major components. Functionalized lipid particulates are designed preferably by incorporation of specific lipid based excipients which can confer targeting ability. The chapter focuses on functionalized lipid particulates like passively targeted liposomes via PEGylation; actively targeted liposomes functionalized via use of monoclonal antibodies, carbohydrates, charged lipids, or other type of targeting ligands; solid lipid nanoparticles and nanostructured lipid carriers functionalized with a targeting ligand; cationic emulsions and other functionalized lipid systems.

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