Using biofunctional magnetic nanoparticles to capture gram-negative bacteria at an ultra-low concentration.

After conjugation to vancomycin (Van), chemically stable and highly magnetic anisotropic FePt magnetic nanoparticles (approximately 4 nm) become water-soluble and capture E. coli at 15 cfu mL(-1).

[1]  Majetich,et al.  Preparation and properties of carbon-coated magnetic nanocrystallites. , 1993, Physical review. B, Condensed matter.

[2]  J. Griffin,et al.  Novel Vancomycin Dimers with Activity against Vancomycin-Resistant Enterococci , 1996 .

[3]  H. Hamann,et al.  Polymer mediated self-assembly of magnetic nanoparticles. , 2002, Journal of the American Chemical Society.

[4]  Zhong Lin Wang,et al.  Temperature Dependence of Cation Distribution and Oxidation State in Magnetic Mn-Fe Ferrite Nanocrystals , 1998 .

[5]  D. Robinette,et al.  Evaluation of an automated microbiologic blood culture device for detection of bacteria in platelet components , 1998, Transfusion.

[6]  C. Walsh Antibiotics: Actions, Origins, Resistance , 2003 .

[7]  F. Neidhardt,et al.  Physiology of the bacterial cell : a molecular approach , 1990 .

[8]  Abraham Ulman,et al.  Activity of Candida rugosa lipase immobilized on gamma-Fe2O3 magnetic nanoparticles. , 2003, Journal of the American Chemical Society.

[9]  Ralph Weissleder,et al.  Magnetic Nanosensors for the Detection of Oligonucleotide Sequences. , 2001, Angewandte Chemie.

[10]  Seyda Bucak,et al.  Protein Separations Using Colloidal Magnetic Nanoparticles , 2003, Biotechnology progress.

[11]  M. Slavik,et al.  Rapid detection of Salmonella typhimurium in chicken carcass wash water using an immunoelectrochemical method. , 2000, Journal of food protection.

[12]  Ralph Weissleder,et al.  Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells , 2000, Nature Biotechnology.

[13]  A. Ribbe,et al.  Self-assembly of cobalt nanoparticle rings. , 2002, Journal of the American Chemical Society.

[14]  Ralph Weissleder,et al.  DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents. , 2002, Journal of the American Chemical Society.

[15]  Sun,et al.  Monodisperse FePt nanoparticles and ferromagnetic FePt nanocrystal superlattices , 2000, Science.

[16]  F. Osterloh Solution self-assembly of magnetic light modulators from exfoliated perovskite and magnetite nanoparticles. , 2002, Journal of the American Chemical Society.