A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
暂无分享,去创建一个
Don C Rockey | D. Rockey | R. Premont | C. Kontos | Richard T Premont | Christopher D Kontos | Songling Liu | Shoukang Zhu | Songling Liu | Shoukang Zhu
[1] M. Birnbaum,et al. Akt1 Regulates a JNK Scaffold during Excitotoxic Apoptosis , 2002, Neuron.
[2] N. Dzimiri,et al. Differential functional expression of human myocardial G protein receptor kinases in left ventricular cardiac diseases. , 2004, European journal of pharmacology.
[3] D. Rockey,et al. Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: endothelial dysfunction in portal hypertension. , 1998, Gastroenterology.
[4] Y. Hirata,et al. Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells. , 1993, The Journal of clinical investigation.
[5] M. Quon,et al. High Density Lipoprotein-induced Endothelial Nitric-oxide Synthase Activation Is Mediated by Akt and MAP Kinases* , 2003, The Journal of Biological Chemistry.
[6] A. Lin,et al. Subcellular Targeting and Agonist-induced Site-specific Phosphorylation of Endothelial Nitric-oxide Synthase* , 2002, The Journal of Biological Chemistry.
[7] D. Rockey,et al. Adenovirus-mediated gene transfer to nonparenchymal cells in normal and injured liver. , 2002, American journal of physiology. Gastrointestinal and liver physiology.
[8] W. Koch,et al. Targeted beta-adrenergic receptor kinase (betaARK1) inhibition by gene transfer in failing human hearts. , 2004, Circulation.
[9] R. Penn,et al. Analysis of the human G protein-coupled receptor kinase 2 (GRK2) gene promoter: regulation by signal transduction systems in aortic smooth muscle cells. , 2000, Circulation.
[10] J. Kountouras,et al. Prolonged bile duct obstruction: a new experimental model for cirrhosis in the rat. , 1984, British journal of experimental pathology.
[11] G. Garcı́a-Cardeña,et al. Endothelial Nitric Oxide Synthase Is Regulated by Tyrosine Phosphorylation and Interacts with Caveolin-1* , 1996, The Journal of Biological Chemistry.
[12] C. Carman,et al. Selective Regulation of Gαq/11 by an RGS Domain in the G Protein-coupled Receptor Kinase, GRK2* , 1999, The Journal of Biological Chemistry.
[13] W. Sessa,et al. Direct Interaction between Endothelial Nitric-oxide Synthase and Dynamin-2 , 2001, The Journal of Biological Chemistry.
[14] Brian A. Hemmings,et al. Carboxyl-Terminal Modulator Protein (CTMP), a Negative Regulator of PKB/Akt and v-Akt at the Plasma Membrane , 2001, Science.
[15] O. Feron,et al. COUNTERBALANCING ALLOSTERIC MODULATORS OF ENDOTHELIAL NITRIC OXIDE SYNTHASE , 1997 .
[16] D. Rockey,et al. Endothelin-1 Activates Endothelial Cell Nitric-oxide Synthase via Heterotrimeric G-protein βγ Subunit Signaling to Protein Kinase B/Akt* , 2003, Journal of Biological Chemistry.
[17] A. Malik,et al. G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[18] P. Penela,et al. β‐arrestin‐ and c‐Src‐dependent degradation of G‐protein‐coupled receptor kinase 2 , 2001, The EMBO journal.
[19] R. Lefkowitz,et al. Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ , 2003, Science.
[20] M. Toruner,et al. Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat. , 1999, Gastroenterology.
[21] W. Sessa,et al. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt , 1999, Nature.
[22] M. Goligorsky,et al. Molecular and functional characterization of the non-isopeptide-selective ETB receptor in endothelial cells. Receptor coupling to nitric oxide synthase. , 1994, The Journal of biological chemistry.
[23] M. Drazner,et al. Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[24] D. Rockey,et al. Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt. , 2003, The Journal of biological chemistry.
[25] B. Doble,et al. GSK-3: tricks of the trade for a multi-tasking kinase , 2003, Journal of Cell Science.
[26] R. Mahley,et al. Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells , 1985, The Journal of cell biology.
[27] M. Nishizawa,et al. Up-regulation of IL-1 receptor through PI3K/Akt is essential for the induction of iNOS gene expression in hepatocytes. , 2004, Journal of hepatology.
[28] W. Koch,et al. Targeted &bgr;-Adrenergic Receptor Kinase (&bgr;ARK1) Inhibition by Gene Transfer in Failing Human Hearts , 2004 .
[29] M. Caron,et al. Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[30] J. York,et al. Tyrosine 1101 of Tie2 Is the Major Site of Association of p85 and Is Required for Activation of Phosphatidylinositol 3-Kinase and Akt , 1998, Molecular and Cellular Biology.
[31] Sumio Watanabe,et al. Immunocytochemical Detection of Desmin in Fat‐Storing Cells (Ito Cells) , 1984, Hepatology.
[33] J. Benovic,et al. G-protein-coupled receptor kinase activity is increased in hypertension. , 1997, The Journal of clinical investigation.
[34] D. Rockey,et al. Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension. , 2000, The Journal of clinical investigation.
[35] J. Liao,et al. Inhibition of Rho-Kinase Leads to Rapid Activation of Phosphatidylinositol 3-Kinase/Protein Kinase Akt and Cardiovascular Protection , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[36] D R Alessi,et al. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? , 2001, Journal of cell science.
[37] Roger Fan,et al. Dynamic activation of endothelial nitric oxide synthase by Hsp90 , 1998, Nature.
[38] C. Ribas,et al. Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases. , 2003, Cellular signalling.