Topographic and cytoarchitectonic organization of thalamic neurons related to their targets in low‐, middle‐, and high‐frequency representations in cat auditory cortex

We studied the topographic organization of thalamic projections upon different ranges of cortical frequency representation. Thalamic neurons were labeled by injecting horseradish peroxidase (HRP) or tritiated bovine serum albumin into auditory cortex. Injections in individual brains were confined to the same range of frequency representation, and distributed through three or four tonotopic cortical fields in order to label as much of the thalamic projection upon a limited range of frequency representation as practicable. Low, middle, and high ranges of the frequency representation were injected in different brains. The spatial organizations of arrays of labeled neurons are described, and each array is divided into a ventral division and lateral posterior complex (lateral part of the posterior thalamic group), both composed mainly of small cells; and a medial division, composed mainly of medium and large cells. The ventral and medial divisions (located laterally and medially within the medial geniculate body (MGB), respectively), both contact the lateral posterior complex which is located rostrally. The HRP cytoarchitecture of the three divisions is described, and the portions of the ventral division corresponding with the physiologically and cytoarchitectonically defined ventral nucleus are identified. Relatively few labeled neurons were found within other thalamic areas.