Mouse macrophage specific knockout of SIRT1 influences macrophage polarization and promotes angiotensin II-induced abdominal aortic aneurysm formation.

[1]  De-Pei Liu,et al.  The Paraoxonase Gene Cluster Protects Against Abdominal Aortic Aneurysm Formation , 2017, Arteriosclerosis, thrombosis, and vascular biology.

[2]  De-Pei Liu,et al.  Age-Associated Sirtuin 1 Reduction in Vascular Smooth Muscle Links Vascular Senescence and Inflammation to Abdominal Aortic Aneurysm. , 2016, Circulation research.

[3]  De-Pei Liu,et al.  Calorie restriction protects against experimental abdominal aortic aneurysms in mice , 2016, The Journal of experimental medicine.

[4]  Jeffrey S. Carson,et al.  Elastin-Derived Peptides Promote Abdominal Aortic Aneurysm Formation by Modulating M1/M2 Macrophage Polarization , 2016, The Journal of Immunology.

[5]  D. Gilroy,et al.  Macrophage development and polarization in chronic inflammation. , 2015, Seminars in immunology.

[6]  B. Baxter,et al.  Inflammatory cell phenotypes in AAAs: their role and potential as targets for therapy. , 2015, Arteriosclerosis, thrombosis, and vascular biology.

[7]  Hongwei Liang,et al.  Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance , 2014, Front. Immunol..

[8]  K. Kent,et al.  Clinical practice. Abdominal aortic aneurysms. , 2014, The New England journal of medicine.

[9]  A. Descoteaux,et al.  Macrophage Cytokines: Involvement in Immunity and Infectious Diseases , 2014, Front. Immunol..

[10]  De-Pei Liu,et al.  The Involvement of NFAT Transcriptional Activity Suppression in SIRT1-Mediated Inhibition of COX-2 Expression Induced by PMA/Ionomycin , 2014, PloS one.

[11]  Yong-ming Yao,et al.  Macrophage Polarization in Inflammatory Diseases , 2014, International journal of biological sciences.

[12]  M. Jeong,et al.  Mesenchymal stem cells reciprocally regulate the M1/M2 balance in mouse bone marrow-derived macrophages , 2014, Experimental & Molecular Medicine.

[13]  P. Amouyel,et al.  Role of Proinflammatory CD68+ Mannose Receptor− Macrophages in Peroxiredoxin-1 Expression and in Abdominal Aortic Aneurysms in Humans , 2013, Arteriosclerosis, thrombosis, and vascular biology.

[14]  H. Kuivaniemi,et al.  Inhibition of Notch1 Signaling Reduces Abdominal Aortic Aneurysm in Mice by Attenuating Macrophage-Mediated Inflammation , 2012, Arteriosclerosis, thrombosis, and vascular biology.

[15]  Zhenggang Yang,et al.  The Full Capacity of AICAR to Reduce Obesity-Induced Inflammation and Insulin Resistance Requires Myeloid SIRT1 , 2012, PloS one.

[16]  Zhong Zhong,et al.  SIRT1 Activators Suppress Inflammatory Responses through Promotion of p65 Deacetylation and Inhibition of NF-κB Activity , 2012, PloS one.

[17]  M. Karin,et al.  NF‐κB and the link between inflammation and cancer , 2012, Immunological reviews.

[18]  Alberto Mantovani,et al.  Macrophage plasticity and polarization: in vivo veritas. , 2012, The Journal of clinical investigation.

[19]  T. Wynn,et al.  Protective and pathogenic functions of macrophage subsets , 2011, Nature Reviews Immunology.

[20]  De-Pei Liu,et al.  SIRT1 Acts as a Modulator of Neointima Formation Following Vascular Injury in Mice , 2011, Circulation research.

[21]  Robert J. Hinchliffe,et al.  Pathophysiology and epidemiology of abdominal aortic aneurysms , 2011, Nature Reviews Cardiology.

[22]  De-Pei Liu,et al.  SIRT1 Suppresses Activator Protein-1 Transcriptional Activity and Cyclooxygenase-2 Expression in Macrophages* , 2009, The Journal of Biological Chemistry.

[23]  B. Jacobsen,et al.  Risk Factors for Abdominal Aortic Aneurysms: A 7-Year Prospective Study: The Tromsø Study, 1994–2001 , 2009, Circulation.

[24]  Tetsuya Matoba,et al.  Cyclophilin A enhances vascular oxidative stress and development of angiotensin II-induced aortic aneurysms , 2009, Nature Medicine.

[25]  I. Lossos,et al.  PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling. , 2008, Blood.

[26]  De-Pei Liu,et al.  Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice. , 2008, Cardiovascular research.

[27]  Y. Ouchi,et al.  Sirt1 modulates premature senescence-like phenotype in human endothelial cells. , 2007, Journal of molecular and cellular cardiology.

[28]  Q. Zhai,et al.  SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. , 2007, Cell metabolism.

[29]  D. Grand,et al.  Inflammatory abdominal aortic aneurysm. , 2007, JAMA.

[30]  A. Sica,et al.  Macrophage polarization comes of age. , 2005, Immunity.

[31]  Toby Lawrence,et al.  IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation , 2005, Nature.

[32]  Silvano Sozzani,et al.  The chemokine system in diverse forms of macrophage activation and polarization. , 2004, Trends in immunology.

[33]  M. Mayo,et al.  Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase , 2004, The EMBO journal.

[34]  A. Daugherty,et al.  Antagonism of AT2 receptors augments Angiotensin II‐induced abdominal aortic aneurysms and atherosclerosis , 2001, British journal of pharmacology.

[35]  K. Bønaa,et al.  Prevalence of and risk factors for abdominal aortic aneurysms in a population-based study : The Tromsø Study. , 2001, American journal of epidemiology.

[36]  P. Shah,et al.  Inflammation, metalloproteinases, and increased proteolysis: an emerging pathophysiological paradigm in aortic aneurysm. , 1997, Circulation.

[37]  J. Pober,et al.  IL-4 and IL-13 activate the JAK2 tyrosine kinase and Stat6 in cultured human vascular endothelial cells through a common pathway that does not involve the gamma c chain. , 1996, The Journal of clinical investigation.