DJ-1/PARK7: A New Therapeutic Target for Neurodegenerative Disorders.
暂无分享,去创建一个
[1] T. Postmus. Genetics of Parkinson's disease , 2018 .
[2] K. Takata,et al. Effects of a DJ-1-Binding Compound on Spatial Learning and Memory Impairment in a Mouse Model of Alzheimer's Disease. , 2016, Journal of Alzheimer's disease : JAD.
[3] E. Melamed,et al. A DJ-1 Based Peptide Attenuates Dopaminergic Degeneration in Mice Models of Parkinson's Disease via Enhancing Nrf2 , 2015, PloS one.
[4] Y. Kitamura,et al. DJ-1-dependent protective activity of DJ-1-binding compound no. 23 against neuronal cell death in MPTP-treated mouse model of Parkinson's disease. , 2015, Journal of pharmacological sciences.
[5] G. Petsko,et al. Transnitrosylation from DJ-1 to PTEN Attenuates Neuronal Cell Death in Parkinson's Disease Models , 2014, The Journal of Neuroscience.
[6] F. Giorgini,et al. DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease. , 2014, Human molecular genetics.
[7] T. Niki,et al. Neuroprotective Function of DJ-1 in Parkinson's Disease , 2013, Oxidative medicine and cellular longevity.
[8] Masaki Tanaka,et al. p62/SQSTM1-Dependent Autophagy of Lewy Body-Like α-Synuclein Inclusions , 2012, PloS one.
[9] H. Yang,et al. DJ-1 protects dopaminergic neurons against rotenone-induced apoptosis by enhancing ERK-dependent mitophagy. , 2012, Journal of molecular biology.
[10] X. Pu,et al. DJ-1 protein protects dopaminergic neurons against 6-OHDA/MG-132-induced neurotoxicity in rats , 2012, Brain Research Bulletin.
[11] C. Isidoro,et al. Defective Autophagy in Parkinson’s Disease: Role of Oxidative Stress , 2012, Molecular Neurobiology.
[12] J. Im,et al. DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway. , 2012, Human molecular genetics.
[13] T. Niki,et al. Transcriptional Activation of Low-Density Lipoprotein Receptor Gene by DJ-1 and Effect of DJ-1 on Cholesterol Homeostasis , 2012, PloS one.
[14] Y. Kitamura,et al. Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats , 2011, Molecular Neurodegeneration.
[15] M. Wilson. The role of cysteine oxidation in DJ-1 function and dysfunction. , 2011, Antioxidants & redox signaling.
[16] T. Niki,et al. Human DJ-1-specific Transcriptional Activation of Tyrosine Hydroxylase Gene* , 2010, The Journal of Biological Chemistry.
[17] J. Im,et al. DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex , 2010, Neuroscience Research.
[18] R. Krüger,et al. Reduced Basal Autophagy and Impaired Mitochondrial Dynamics Due to Loss of Parkinson's Disease-Associated Protein DJ-1 , 2010, PloS one.
[19] K. Takata,et al. Oxidative Neurodegeneration Is Prevented by UCP0045037, an Allosteric Modulator for the Reduced Form of DJ-1, a Wild-Type of Familial Parkinson’s Disease-Linked PARK7 , 2009, International journal of molecular sciences.
[20] Wei Jiang,et al. Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. , 2009, The Journal of clinical investigation.
[21] He-Jin Lee,et al. Clearance and deposition of extracellular alpha-synuclein aggregates in microglia. , 2008, Biochemical and biophysical research communications.
[22] Y. Kitamura,et al. DJ‐1‐binding compounds prevent oxidative stress‐induced cell death and movement defect in Parkinson’s disease model rats , 2008, Journal of neurochemistry.
[23] K. Takata,et al. DJ-1 Protects against Neurodegeneration Caused by Focal Cerebral Ischemia and Reperfusion in Rats , 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[24] Jun Fan,et al. DJ-1 Decreases Bax Expression through Repressing p53 Transcriptional Activity* , 2008, Journal of Biological Chemistry.
[25] Kazuyuki Takata,et al. PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson’s disease rat model , 2006, Neurobiology of Disease.
[26] Takeshi Iwatsubo,et al. Roles of distinct cysteine residues in S-nitrosylation and dimerization of DJ-1. , 2006, Biochemical and biophysical research communications.
[27] Andrew B West,et al. Molecular pathophysiology of Parkinson's disease. , 2005, Annual review of neuroscience.
[28] Steven P Gygi,et al. The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis. , 2005, Human molecular genetics.
[29] Thomas Floss,et al. Sensitivity to Oxidative Stress in DJ-1-Deficient Dopamine Neurons: An ES- Derived Cell Model of Primary Parkinsonism , 2004, PLoS biology.
[30] A. Abeliovich,et al. DJ-1 Is a Redox-Dependent Molecular Chaperone That Inhibits α-Synuclein Aggregate Formation , 2004, PLoS biology.
[31] Peter T. Lansbury,et al. Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy , 2004, Science.
[32] Tomoya Kinumi,et al. Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells. , 2004, Biochemical and biophysical research communications.
[33] Keith D Wilkinson,et al. Familial Parkinson's Disease-associated L166P Mutation Disrupts DJ-1 Protein Folding and Function* , 2004, Journal of Biological Chemistry.
[34] T. Niki,et al. DJ‐1 has a role in antioxidative stress to prevent cell death , 2004, EMBO reports.
[35] Vincenzo Bonifati,et al. Linking DJ-1 to neurodegeneration offers novel insights for understanding the pathogenesis of Parkinson’s disease , 2004, Journal of Molecular Medicine.
[36] Liang Tong,et al. Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease* , 2003, Journal of Biological Chemistry.
[37] Jeremy N. Skepper,et al. α-Synuclein Is Degraded by Both Autophagy and the Proteasome* , 2003, Journal of Biological Chemistry.
[38] T. Niki,et al. DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex. , 2003, Molecular cancer research : MCR.
[39] Patrizia Rizzu,et al. Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism , 2002, Science.
[40] Hiroyoshi Ariga,et al. DJ-1 Positively Regulates the Androgen Receptor by Impairing the Binding of PIASxα to the Receptor* , 2001, The Journal of Biological Chemistry.
[41] Shinsei Minoshima,et al. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase , 2000, Nature Genetics.
[42] K. Takata,et al. Protection against dopaminergic neurodegeneration in Parkinson's disease-model animals by a modulator of the oxidized form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7. , 2011, Journal of pharmacological sciences.
[43] David W. Miller,et al. DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. , 2011, Human molecular genetics.
[44] K. Takata,et al. Protection against oxidative stress-induced neurodegeneration by a modulator for DJ-1, the wild-type of familial Parkinson's disease-linked PARK7. , 2009, Journal of pharmacological sciences.
[45] He-Jin Lee,et al. Assembly-dependent endocytosis and clearance of extracellular alpha-synuclein. , 2008, The international journal of biochemistry & cell biology.
[46] Leonidas Stefanis,et al. Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. , 2004, Science.