Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo
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P. Siegel | J. Dusseault | L. Larose | Mélissa Labelle-Côté | S. Ismaiel | Aude Picard-Cloutier | Aude Picard-Cloutier
[1] G. Bourret,et al. Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice. , 2011, American journal of physiology. Endocrinology and metabolism.
[2] J. Condeelis,et al. An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion. , 2011, Cancer research.
[3] J. Condeelis,et al. Nck1 and Grb2 localization patterns can distinguish invadopodia from podosomes. , 2011, European journal of cell biology.
[4] A. Boggs,et al. c-Src differentially regulates the functions of microtentacles and invadopodia , 2010, Oncogene.
[5] S. Weed,et al. Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation , 2010, Journal of Cell Science.
[6] A. Pendergast,et al. Abl Kinases Are Required for Invadopodia Formation and Chemokine-induced Invasion* , 2010, The Journal of Biological Chemistry.
[7] D. W. Kim,et al. Elevated c-Src and c-Yes expression in malignant skin cancers , 2010, Journal of experimental & clinical cancer research : CR.
[8] W. Kolch,et al. The Bcr-Abl kinase regulates the actin cytoskeleton via a GADS/Slp-76/Nck1 adaptor protein pathway. , 2010, Cellular signalling.
[9] T. Majima,et al. Adaptor Protein Crk Induces Src-Dependent Activation of p38 MAPK in Regulation of Synovial Sarcoma Cell Proliferation , 2009, Molecular Cancer Research.
[10] S. Stylli,et al. Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation , 2009, Journal of Cell Science.
[11] A. Huttenlocher,et al. FAK alters invadopodia and focal adhesion composition and dynamics to regulate breast cancer invasion , 2009, The Journal of cell biology.
[12] B. Mayer,et al. A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors , 2008, Journal of Cell Science.
[13] A. Luini,et al. Multiple regulatory inputs converge on cortactin to control invadopodia biogenesis and extracellular matrix degradation , 2008, Journal of Cell Science.
[14] Thamara K. Dayarathna,et al. Phosphorylated YDXV Motifs and Nck SH2/SH3 Adaptors Act Cooperatively To Induce Actin Reorganization , 2008, Molecular and Cellular Biology.
[15] L. Larue,et al. Cutaneous melanoma in genetically modified animals. , 2007, Pigment cell research.
[16] K. Flaherty,et al. Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levels , 2007, British Journal of Cancer.
[17] Wen-Lin Kuo,et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. , 2006, Cancer cell.
[18] Jean-Philippe Brunet,et al. The melanocyte differentiation program predisposes to metastasis after neoplastic transformation , 2005, Nature Genetics.
[19] U. Weidle,et al. Analysis of differential gene expression in human melanocytic tumour lesions by custom made oligonucleotide arrays , 2005, British Journal of Cancer.
[20] Wenjun Guo,et al. Integrin signalling during tumour progression , 2004, Nature Reviews Molecular Cell Biology.
[21] Roberto Buccione,et al. Foot and mouth: podosomes, invadopodia and circular dorsal ruffles , 2004, Nature Reviews Molecular Cell Biology.
[22] M. McNiven,et al. The role of dynamin in the assembly and function of podosomes and invadopodia. , 2004, Frontiers in bioscience : a journal and virtual library.
[23] M. Lacroix,et al. Relevance of Breast Cancer Cell Lines as Models for Breast Tumours: An Update , 2004, Breast Cancer Research and Treatment.
[24] J. Segall,et al. Intravital imaging of cell movement in tumours , 2003, Nature Reviews Cancer.
[25] Guido Tarone,et al. Positional control of cell fate through joint integrin/receptor protein kinase signaling. , 2003, Annual review of cell and developmental biology.
[26] Martin Fussenegger,et al. Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types. , 2003, Biotechnology and bioengineering.
[27] T. Pawson,et al. The Murine Nck SH2/SH3 Adaptors Are Important for the Development of Mesoderm-Derived Embryonic Structures and for Regulating the Cellular Actin Network , 2003, Molecular and Cellular Biology.
[28] T. Kennedy,et al. The Adaptor Protein Nck-1 Couples the Netrin-1 Receptor DCC (Deleted in Colorectal Cancer) to the Activation of the Small GTPase Rac1 through an Atypical Mechanism* , 2002, The Journal of Biological Chemistry.
[29] L. Buday,et al. The Nck family of adapter proteins: regulators of actin cytoskeleton. , 2002, Cellular signalling.
[30] J. Guan,et al. Nck-2 interacts with focal adhesion kinase and modulates cell motility. , 2002, International Journal of Biochemistry and Cell Biology.
[31] Lida Guo,et al. A Critical Role of the PINCH-Integrin-linked Kinase Interaction in the Regulation of Cell Shape Change and Migration* , 2002, The Journal of Biological Chemistry.
[32] S. Philippou,et al. Modulation of angiogenesis and tumorigenicity of human melanocytic cells by vascular endothelial growth factor and basic fibroblast growth factor. , 2001, Cancer research.
[33] Chad A. Cowan,et al. The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals , 2001, Nature.
[34] W. Li,et al. The SH2 and SH3 adapter Nck: a two-gene family and a linker between tyrosine kinases and multiple signaling networks. , 2000, Histology and histopathology.
[35] B. Mayer,et al. Activation of the Abl Tyrosine Kinase in Vivo by Src Homology 3 Domains from the Src Homology 2/Src Homology 3 Adaptor Nck* , 1999, The Journal of Biological Chemistry.
[36] L. Buday,et al. Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins. , 1999, Biochimica et biophysica acta.
[37] S. Aota,et al. Molecular diversity of cell-matrix adhesions. , 1999, Journal of cell science.
[38] Y. Tu,et al. The LIM-Only Protein PINCH Directly Interacts with Integrin-Linked Kinase and Is Recruited to Integrin-Rich Sites in Spreading Cells , 1999, Molecular and Cellular Biology.
[39] L. Quilliam,et al. Identification of Grb4/Nckβ, a Src Homology 2 and 3 Domain-containing Adapter Protein Having Similar Binding and Biological Properties to Nck* , 1999, The Journal of Biological Chemistry.
[40] Y. Tu,et al. Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways. , 1998, Molecular biology of the cell.
[41] J. McCarty,et al. The Nck SH2/SH3 adaptor protein: a regulator of multiple intracellular signal transduction events , 1998, BioEssays : news and reviews in molecular, cellular and developmental biology.
[42] Gerhard Christofori,et al. A causal role for E-cadherin in the transition from adenoma to carcinoma , 1998, Nature.
[43] A. Lane,et al. Nck Recruitment to Eph Receptor, EphB1/ELK, Couples Ligand Activation to c-Jun Kinase* , 1998, The Journal of Biological Chemistry.
[44] T. Pawson,et al. Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells , 1997, The EMBO journal.
[45] L. Larose,et al. A Casein Kinase I Activity Is Constitutively Associated with Nck* , 1997, The Journal of Biological Chemistry.
[46] D. Lawe,et al. The Nck SH2/SH3 adaptor protein is present in the nucleus and associates with the nuclear protein SAM68 , 1997, Oncogene.
[47] T. Yoneda,et al. E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model. , 1996, Cancer research.
[48] A. Horwitz,et al. Tyrosine phosphorylation and cytoskeletal tension regulate the release of fibroblast adhesions , 1995, The Journal of cell biology.
[49] F. Giancotti,et al. Integrin-mediated adhesion and signaling in tumorigenesis. , 1994, Biochimica et biophysica acta.
[50] I. G. Fantus,et al. Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics. , 1994, The Journal of biological chemistry.
[51] M. White,et al. Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[52] R L Juliano,et al. Adhesion molecules in cancer: the role of integrins. , 1993, Current opinion in cell biology.
[53] S. Rhee,et al. Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP , 1992, Molecular and cellular biology.
[54] T. Hunter,et al. The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-gamma 1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatment , 1992, Molecular and cellular biology.
[55] H. Hanafusa,et al. The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels. , 1992, Molecular and cellular biology.
[56] A. Ullrich,et al. The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors , 1992, Molecular and cellular biology.
[57] Richard O. Hynes,et al. Integrins: Versatility, modulation, and signaling in cell adhesion , 1992, Cell.
[58] W. Birchmeier,et al. E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells , 1991, The Journal of cell biology.
[59] J. Lehmann,et al. Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3. , 1990, Nucleic acids research.
[60] I. G. Fantus,et al. Pervanadate [peroxide(s) of vanadate] mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase. , 1989, Biochemistry.
[61] W. T. Chen,et al. Proteolytic activity of specialized surface protrusions formed at rosette contact sites of transformed cells. , 1989, The Journal of experimental zoology.
[62] W. Clark,et al. Inhibition of metastases of a human melanoma xenograft by monoclonal antibody to the GD2/GD3 gangliosides. , 1989, Journal of the National Cancer Institute.
[63] I. G. Fantus,et al. Peroxide(s) of vanadium: a novel and potent insulin-mimetic agent which activates the insulin receptor kinase. , 1987, Biochemical and biophysical research communications.
[64] M. Brattain,et al. Establishment of mouse colonic carcinoma cell lines with different metastatic properties. , 1980, Cancer research.
[65] J. Garland. The New England Journal of Medicine. , 1961, Canadian Medical Association journal.
[66] J.,et al. The New England Journal of Medicine , 2012 .
[67] J. Segall,et al. Molecular mechanisms of invadopodium formation: the role of the N-WASP–Arp2/3 complex pathway and cofilin , 2005 .
[68] P. Meltzer,et al. High frequency of BRAF mutations in nevi , 2003, Nature Genetics.
[69] S. Dedhar,et al. Mini-Review Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling , 2001 .
[70] M. Takeichi. Morphogenetic roles of classic cadherins. , 1995, Current opinion in cell biology.
[71] B. Mayer,et al. Characterization of p47gag-crk, a novel oncogene product with sequence similarity to a putative modulatory domain of protein-tyrosine kinases and phospholipase C. , 1988, Cold Spring Harbor symposia on quantitative biology.