Characterization of a polysaccharide from Eupolyphaga sinensis walker and its effective antitumor activity via lymphocyte activation.

[1]  Guangyong Peng,et al.  Exhaustion and senescence: two crucial dysfunctional states of T cells in the tumor microenvironment , 2019, Cellular & Molecular Immunology.

[2]  Kunlin Wu,et al.  B7H4 expression in tumor cells impairs CD8 T cell responses and tumor immunity , 2019, Cancer Immunology, Immunotherapy.

[3]  Candong Li,et al.  Traditional Chinese Medicine-Guided Dietary Intervention for Male Youth Undergoing Drug Detoxification: A Randomized Controlled Trial , 2019, Evidence-based complementary and alternative medicine : eCAM.

[4]  Zhilei Wang,et al.  Caffeine enhances the anti-tumor effect of 5-fluorouracil via increasing the production of reactive oxygen species in hepatocellular carcinoma , 2019, Medical Oncology.

[5]  Xianwen Ren,et al.  Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma , 2019, Cell.

[6]  Tongtong Zhang,et al.  Binding of the polysaccharide from Acanthopanax giraldii Harms to toll-like receptor 4 activates macrophages. , 2019, Journal of ethnopharmacology.

[7]  W. Lau,et al.  Management of patients with hepatocellular carcinoma and portal vein tumour thrombosis: comparing east and west. , 2019, The lancet. Gastroenterology & hepatology.

[8]  S. Palanisamy,et al.  Studies on structural properties and immune-enhancing activities of glycomannans from Schizophyllum commune. , 2019, Carbohydrate polymers.

[9]  C. de Castro,et al.  Bifidobacterium bifidum presents on the cell surface a complex mixture of glucans and galactans with different immunological properties. , 2019, Carbohydrate polymers.

[10]  Jian-zhong Wu,et al.  Monoclonal antibody AC10364 inhibits cell proliferation in 5-fluorouracil resistant hepatocellular carcinoma via apoptotic pathways , 2019, OncoTargets and therapy.

[11]  Wenyuan Gao,et al.  Purification, characterization and immunomodulatory activity of fructans from Polygonatum odoratum and P. cyrtonema. , 2019, Carbohydrate polymers.

[12]  É. Vivier,et al.  Targeting natural killer cells in solid tumors , 2019, Cellular & Molecular Immunology.

[13]  Quanbin Zhang,et al.  A heteropolysaccharide from Saccharina japonica with immunomodulatory effect on RAW 264.7 cells. , 2018, Carbohydrate polymers.

[14]  J. González‐Gallego,et al.  Sorafenib resistance in hepatocarcinoma: role of hypoxia-inducible factors , 2018, Experimental & Molecular Medicine.

[15]  W. Xu,et al.  Structural analysis and immunomodulatory effect of polysaccharide from Atractylodis macrocephalae Koidz. on bovine lymphocytes. , 2017, Carbohydrate polymers.

[16]  J. Dou,et al.  Enhanced antitumor activity of gemcitabine by polysaccharide-induced NK cell activation and immune cytotoxicity reduction in vitro/vivo. , 2017, Carbohydrate polymers.

[17]  Ruibing Wang,et al.  Post-screening characterisation and in vivo evaluation of an anti-inflammatory polysaccharide fraction from Eucommia ulmoides. , 2017, Carbohydrate polymers.

[18]  G. Abou-Alfa,et al.  The role (if any) of chemotherapy in hepatocellular carcinoma. , 2017, The lancet. Gastroenterology & hepatology.

[19]  Jie Yu,et al.  A polysaccharide component from Strongylocentrotus nudus eggs inhibited hepatocellular carcinoma in mice by activating T lymphocytes. , 2017, Oncology letters.

[20]  R. Lanzetta,et al.  The polysaccharide and low molecular weight components of Opuntia ficus indica cladodes: Structure and skin repairing properties. , 2017, Carbohydrate polymers.

[21]  Xiao-rui Zhang,et al.  Toll-like receptor 4-related immunostimulatory polysaccharides: Primary structure, activity relationships, and possible interaction models. , 2016, Carbohydrate polymers.

[22]  T. Pawlik,et al.  Hepatocellular carcinoma: From diagnosis to treatment. , 2016, Surgical oncology.

[23]  J. D. Di Santo,et al.  IL‐2 and IL‐15 regulate CD8+ memory T‐cell differentiation but are dispensable for protective recall responses , 2015, European journal of immunology.

[24]  M. Coimbra,et al.  Structure-function relationships of immunostimulatory polysaccharides: A review. , 2015, Carbohydrate polymers.

[25]  Yuguang Du,et al.  Molecular shape and immunogenicity of meningococcal polysaccharide group A conjugate vaccine. , 2015, Vaccine.

[26]  Hongxiang Sun,et al.  Activation of RAW264.7 macrophages by the polysaccharide from the roots of Actinidia eriantha and its molecular mechanisms. , 2015, Carbohydrate polymers.

[27]  Wing Lam,et al.  Safety Surveillance of Traditional Chinese Medicine: Current and Future , 2015, Drug Safety.

[28]  Weina Ma,et al.  Eupolyphaga sinensis Walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling , 2014, Scientific Reports.

[29]  M. Zhang,et al.  The anti-lung cancer activity of SEP is mediated by the activation and cytotoxicity of NK cells via TLR2/4 in vivo. , 2014, Biochemical pharmacology.

[30]  Y. Zhan,et al.  Eupolyphaga sinensis Walker inhibits human chronic myeloid leukemia cell K562 growth by inducing G2-M phase cell cycle arrest and targeting EGFR signaling pathway and in S180 tumor-bearing mice. , 2014, Environmental toxicology and pharmacology.

[31]  G. Sassaki,et al.  Polysaccharides from green and black teas and their protective effect against murine sepsis , 2013 .

[32]  Feng Chen,et al.  Structural characteristics and antioxidant activities of polysaccharides from longan seed. , 2013, Carbohydrate polymers.

[33]  Sung-Joon Lee,et al.  Structural analysis of immunostimulating sulfated polysaccharides from Ulva pertusa. , 2012, Carbohydrate research.

[34]  F. Valeriote,et al.  New isocoumarins and alkaloid from Chinese insect medicine, Eupolyphaga sinensis Walker. , 2012, Fitoterapia.

[35]  M. Hoogenkamp,et al.  Structural investigation of an extracellular polysaccharide produced by the cariogenic bacterium Streptococcus mutans strain UA159. , 2012, Carbohydrate polymers.

[36]  Antony Bacic,et al.  Determining the polysaccharide composition of plant cell walls , 2012, Nature Protocols.

[37]  Chenhuan Yu,et al.  Antitumor effects and chemical compositions of Eupolyphaga sinensis Walker ethanol extract. , 2012, Journal of ethnopharmacology.

[38]  A. Cerwenka,et al.  Natural Killer Cells and Solid Tumors , 2011, Journal of Innate Immunity.

[39]  Cunbao Liu,et al.  A Bi-Functional Anti-Thrombosis Protein Containing Both Direct-Acting Fibrin(ogen)olytic and Plasminogen-Activating Activities , 2011, PLoS ONE.

[40]  H. Cai,et al.  Effects of dahuangzhechong pills on cytokines and mitogen activated protein kinase activation in rats with hepatic fibrosis. , 2010, Journal of ethnopharmacology.

[41]  T. Grindley,et al.  Isolation of phosphorylated polysaccharides from algae: the immunostimulatory principle of Chlorella pyrenoidosa. , 2010, Carbohydrate research.

[42]  Beat Ernst,et al.  From carbohydrate leads to glycomimetic drugs , 2009, Nature Reviews Drug Discovery.

[43]  T. Ishii,et al.  Blocking Effect of Anti-Dectin-1 Antibodies on the Anti-tumor Activity of 1,3-β-Glucan and the Binding of Dectin-1 to 1,3-β-Glucan , 2007 .

[44]  S. Melnick,et al.  Mechanism of macrophage activation by (1,4)-α-d-glucan isolated from Tinospora cordifolia , 2006 .

[45]  Zhien Li,et al.  In vivo antitumor and immunomodulation activities of different molecular weight lambda-carrageenans from Chondrus ocellatus. , 2004, Pharmacological research.

[46]  S. B. Han,et al.  Toll-like receptor-mediated activation of B cells and macrophages by polysaccharide isolated from cell culture of Acanthopanax senticosus. , 2003, International immunopharmacology.

[47]  H. Shiku Importance of CD4+ Helper T-cells in Antitumor Immunity , 2003, International journal of hematology.

[48]  K. Karaca,et al.  Nitric oxide production by chicken macrophages activated by Acemannan, a complex carbohydrate extracted from Aloe vera. , 1995, International journal of immunopharmacology.

[49]  Zhenjing Li,et al.  Structural characterisation and immunomodulatory activity of polysaccharides from white asparagus skin. , 2020, Carbohydrate polymers.

[50]  Christopher B Wilson,et al.  Regulation of interferon-gamma during innate and adaptive immune responses. , 2007, Advances in immunology.

[51]  C. Gonçalves,et al.  [Hepatocellular carcinoma]. , 1988, Arquivos de gastroenterologia.