Cotranscriptional Set 2 Methylation of Histone H 3 Lysine 36 Recruits a Repressive Rpd 3 Complex

Michael-Christopher Keogh,1 Siavash K. Kurdistani,2 Stephanie A. Morris,3 Seong Hoon Ahn,1,7 Vladimir Podolny,1 Sean R. Collins,4 Maya Schuldiner,4 Kayu Chin,5 Thanuja Punna,5 Natalie J. Thompson,5 Charles Boone,5,6 Andrew Emili,5,6 Jonathan S. Weissman,4 Timothy R. Hughes,5,6 Brian D. Strahl,3 Michael Grunstein,2 Jack F. Greenblatt,5,6,* Stephen Buratowski,1,* and Nevan J. Krogan5,6,8 1Department of Biological Chemistry and Molecular Pharmacology Harvard Medical School 240 Longwood Avenue Boston, Massachusetts 02115 2Department of Biological Chemistry David Geffen School of Medicine University of California, Los Angeles Los Angeles, California 90095 3Department of Biochemistry and Biophysics University of North Carolina School of Medicine Chapel Hill, North Carolina 27599 4Howard Hughes Medical Institute Department of Cellular and Molecular Pharmacology University of California, San Francisco Genentech Hall S472C 600 16th Street San Francisco, California 94143 5Banting and Best Department of Medical Research University of Toronto 112 College Street Toronto, Ontario M5G 1L6 Canada 6Department of Medical Genetics and Microbiology University of Toronto 1 Kings College Circle Toronto, Ontario M5S 1A8 Canada

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