O-Methylation of phenolic compounds with dimethyl carbonate under solid/liquid phase transfer system

The industrially important alkyl aryl ethers, of which anisole is the simplest form, can be synthesized by reacting the corresponding phenols with the environmentally benign dimethyl carbonate (DMC). The reaction is carried out under mild conditions of temperature and pressure. Excellent yields and selectivity of product were obtained after a few hours of reaction.

[1]  Yue Fu,et al.  Vapor-phase reactions of catechol with dimethyl carbonate. Part I. O-Methylation of catechol over alumina , 1998 .

[2]  I. Shimizu,et al.  Convenient O-Methylation of Phenols with Dimethyl Carbonate , 1998 .

[3]  M. Selva,et al.  A Continuous-Flow O-Methylation of Phenols with Dimethyl Carbonate in a Continuously Fed Stirred Tank Reactor , 1999 .

[4]  M. Selva,et al.  Dimethylcarbonate for eco-friendly methylation reactions. , 2001, Chemosphere.

[5]  M. Selva,et al.  Simplify gas-liquid phase transfer catalysis , 1995 .

[6]  Yue Fu,et al.  Vapor-phase reactions of catechol with dimethyl carbonate. Part III: Selective synthesis of veratrole over alumina loaded with potassium nitrate , 1999 .

[7]  F. Trotta,et al.  Reactions of dimethyl carbonate with nucleophiles under gas-liquid phase-transfer catalysis (GL-PTC) conditions , 1989 .

[8]  Pietro Tundo,et al.  Continuous-flow processes under gas-liquid phase-transfer catalysis (GL-PTC) conditions: the reaction of dialkyl carbonates with phenols, alcohols, and mercaptans , 1988 .

[9]  F. Trotta,et al.  Esters and orthoesters as alkylating agents at high temperature. Applications to continuous-flow processes , 1992 .

[10]  A. Perosa,et al.  Alkyl Methyl Carbonates as Methylating Agents. The O-Methylation of Phenols , 2000 .

[11]  M. Lissel,et al.  Dimethylcarbonat als Methylierungsmittel unter phasen-transfer-katalytischen Bedingungen , 1986 .

[12]  Y. Ono,et al.  Dimethyl carbonate for environmentally benign reactions , 1996 .

[13]  Stuart Thompson.  Trends in portable instrumentation , 1984 .

[14]  Yoshio Ono,et al.  Catalysis in the Production and Reactions of Dimethyl Carbonate, an Environmentally Benign Building-Block , 1997 .

[15]  Yue Fu,et al.  Vapor-phase reactions of catechol with dimethyl carbonate. Part II. Selective synthesis of guaiacol over alumina loaded with alkali hydroxide , 1998 .

[16]  Y. Ono,et al.  Selective O-methylation of phenol with dimethyl carbonate over X-zeolites , 1993 .

[17]  J. Senet,et al.  Pentaalkylguanidines as etherification and esterification catalysts , 1990 .

[18]  F. Trotta,et al.  Gas-liquid phase-transfer catalysis: a new continuous-flow method in organic synthesis , 1989 .