Selective activation mechanisms of Wnt signaling pathways.
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[1] P. Sternberg,et al. Ror receptor tyrosine kinases: orphans no more. , 2008, Trends in cell biology.
[2] Yan Liu,et al. Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase , 2008, Journal of cellular biochemistry.
[3] Gun-Hwa Kim,et al. Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements , 2008, The Journal of cell biology.
[4] Dianqing Wu,et al. Wnt3a-Mediated Formation of Phosphatidylinositol 4,5-Bisphosphate Regulates LRP6 Phosphorylation , 2008, Science.
[5] Xi He,et al. DKK1 Antagonizes Wnt Signaling without Promotion of LRP6 Internalization and Degradation* , 2008, Journal of Biological Chemistry.
[6] Y. Minami,et al. Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. , 2008, Developmental Cell.
[7] T. Michiue,et al. Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling. , 2008, Developmental cell.
[8] I. Komuro,et al. IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis , 2008, Nature.
[9] K. Maiese,et al. The Wnt signaling pathway: aging gracefully as a protectionist? , 2008, Pharmacology & therapeutics.
[10] Hideki Yamamoto,et al. Tumor formation due to abnormalities in the β‐catenin‐independent pathway of Wnt signaling , 2008, Cancer science.
[11] Y. Minami,et al. Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2 , 2008, BMC Molecular Biology.
[12] J. Vincent,et al. Endocytosis: A Positive or a Negative Influence on Wnt Signalling? , 2008, Traffic.
[13] Chika Yokota,et al. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions , 2007, Development.
[14] A. Bafico,et al. Analysis of Endogenous LRP6 Function Reveals a Novel Feedback Mechanism by Which Wnt Negatively Regulates Its Receptor , 2007, Molecular and Cellular Biology.
[15] Mariann Bienz,et al. Dynamic recruitment of axin by Dishevelled protein assemblies , 2007, Journal of Cell Science.
[16] Christof Niehrs,et al. Wnt Induces LRP6 Signalosomes and Promotes Dishevelled-Dependent LRP6 Phosphorylation , 2007, Science.
[17] Yoshiki Higuchi,et al. The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization , 2007, Nature Structural &Molecular Biology.
[18] K. Steel,et al. Wnt5a functions in planar cell polarity regulation in mice. , 2007, Developmental biology.
[19] Gun-Hwa Kim,et al. Essential role for β‐arrestin 2 in the regulation of Xenopus convergent extension movements , 2007, The EMBO journal.
[20] D. Wedlich,et al. Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway. , 2007, Developmental cell.
[21] G. Schulte,et al. Inhibition of endocytosis blocks Wnt signalling to β‐catenin by promoting dishevelled degradation , 2007, Acta physiologica.
[22] Vítězslav Bryja,et al. β-Arrestin is a necessary component of Wnt/β-catenin signaling in vitro and in vivo , 2007, Proceedings of the National Academy of Sciences.
[23] Hideki Yamamoto,et al. Multiplicity of the interactions of Wnt proteins and their receptors. , 2007, Cellular signalling.
[24] Hideki Yamamoto,et al. Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling. , 2007, The Biochemical journal.
[25] C. Niehrs,et al. Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/beta catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek. , 2007, Genes & development.
[26] P. Polakis. The many ways of Wnt in cancer. , 2007, Current opinion in genetics & development.
[27] C. Niehrs,et al. Function and biological roles of the Dickkopf family of Wnt modulators , 2006, Oncogene.
[28] Y. Minami,et al. Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration , 2006, The Journal of cell biology.
[29] R. Nusse,et al. Wnt Signaling: Multiple Pathways, Multiple Receptors, and Multiple Transcription Factors* , 2006, Journal of Biological Chemistry.
[30] Akira Kikuchi,et al. Caveolin Is Necessary for Wnt-3a-Dependent Internalization of LRP6 and Accumulation of β-Catenin , 2006 .
[31] Hsien-yu Wang,et al. Structure-function analysis of Frizzleds. , 2006, Cellular signalling.
[32] Sangdun Choi,et al. Mouse Cristin/R-spondin Family Proteins Are Novel Ligands for the Frizzled 8 and LRP6 Receptors and Activate β-Catenin-dependent Gene Expression* , 2006, Journal of Biological Chemistry.
[33] H. Bellen,et al. Internalization is required for proper Wingless signaling in Drosophila melanogaster , 2006, The Journal of cell biology.
[34] J. Larraín,et al. Syndecan-4 regulates non-canonical Wnt signalling and is essential for convergent and extension movements in Xenopus embryos , 2006, Nature Cell Biology.
[35] R. Nusse,et al. Purified Wnt5a Protein Activates or Inhibits β-Catenin–TCF Signaling Depending on Receptor Context , 2006, PLoS biology.
[36] P. Dolan,et al. The Low Density Lipoprotein Receptor-related Protein 6 Interacts with Glycogen Synthase Kinase 3 and Attenuates Activity* , 2006, Journal of Biological Chemistry.
[37] J. Vincent,et al. Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs , 2005, Development.
[38] Xi He,et al. A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation , 2005, Nature.
[39] Christof Niehrs,et al. Casein kinase 1 γ couples Wnt receptor activation to cytoplasmic signal transduction , 2005, Nature.
[40] M. Kirkham,et al. Erratum to “Clathrin-independent endocytosis: New insights into caveolae and non-caveolar lipid raft carriers” [Biochim. Biophys. Acta 1744 (2005) 273–286] , 2005 .
[41] M. Kirkham,et al. Clathrin-independent endocytosis: new insights into caveolae and non-caveolar lipid raft carriers. , 2005, Biochimica et biophysica acta.
[42] Xi He,et al. SOST Is a Ligand for LRP5/LRP6 and a Wnt Signaling Inhibitor* , 2005, Journal of Biological Chemistry.
[43] C. Lobe,et al. Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling. , 2005, Cancer research.
[44] Peng Liu,et al. Sclerostin Binds to LRP5/6 and Antagonizes Canonical Wnt Signaling* , 2005, Journal of Biological Chemistry.
[45] N. Perrimon,et al. Functional Genomic Analysis of the Wnt-Wingless Signaling Pathway , 2005, Science.
[46] L. Liaw,et al. Collagen Triple Helix Repeat Containing 1, a Novel Secreted Protein in Injured and Diseased Arteries, Inhibits Collagen Expression and Promotes Cell Migration , 2005, Circulation research.
[47] J. Filmus,et al. The Loss of Glypican-3 Induces Alterations in Wnt Signaling* , 2005, Journal of Biological Chemistry.
[48] Xinhua Lin,et al. Functions of heparan sulfate proteoglycans in cell signaling during development , 2004, Development.
[49] R. Nusse,et al. The Wnt signaling pathway in development and disease. , 2004, Annual review of cell and developmental biology.
[50] Wange Lu,et al. Mammalian Ryk Is a Wnt Coreceptor Required for Stimulation of Neurite Outgrowth , 2004, Cell.
[51] Ajamete Kaykas,et al. WNT and β-catenin signalling: diseases and therapies , 2004, Nature Reviews Genetics.
[52] D. Schafer. Regulating Actin Dynamics at Membranes: A Focus on Dynamin , 2004, Traffic.
[53] Hideki Yamamoto,et al. Wnt-3a and Dvl Induce Neurite Retraction by Activating Rho-Associated Kinase , 2004, Molecular and Cellular Biology.
[54] Xi He,et al. LDL receptor-related proteins 5 and 6 in Wnt/β-catenin signaling: Arrows point the way , 2004, Development.
[55] J. Nathans,et al. Vascular Development in the Retina and Inner Ear Control by Norrin and Frizzled-4, a High-Affinity Ligand-Receptor Pair , 2004, Cell.
[56] Xi He,et al. A mechanism for Wnt coreceptor activation. , 2004, Molecular cell.
[57] J. Couchman. Syndecans: proteoglycan regulators of cell-surface microdomains? , 2003, Nature Reviews Molecular Cell Biology.
[58] M. Gonzalez-Gaitan. Endocytic trafficking during Drosophila development , 2003, Mechanisms of Development.
[59] Liaoyuan A. Hu,et al. Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4 , 2003, Science.
[60] Jeffrey D. Axelrod,et al. A Second Canon , 2003 .
[61] Nobuyuki Onishi,et al. The receptor tyrosine kinase Ror2 is involved in non‐canonical Wnt5a/JNK signalling pathway , 2003, Genes to cells : devoted to molecular & cellular mechanisms.
[62] M. Bienz,et al. A Role of Dishevelled in Relocating Axin to the Plasma Membrane during Wingless Signaling , 2003, Current Biology.
[63] N. Ueno,et al. Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis , 2003, Development.
[64] John B. Thomas,et al. Wnt-mediated axon guidance via the Drosophila Derailed receptor , 2003, Nature.
[65] A. M. Arias. Wnts as morphogens? The view from the wing of Drosophila , 2003, Nature Reviews Molecular Cell Biology.
[66] Sandra L. Schmid,et al. Regulated portals of entry into the cell , 2003, Nature.
[67] S. Woodman,et al. Caveolae: From Cell Biology to Animal Physiology , 2002, Pharmacological Reviews.
[68] Christof Niehrs,et al. Kremen proteins are Dickkopf receptors that regulate Wnt/β-catenin signalling , 2002, Nature.
[69] Liaoyuan A. Hu,et al. β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[70] Stuart A. Aaronson,et al. Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow , 2001, Nature Cell Biology.
[71] Cyrille Alexandre,et al. Regulated Endocytic Routing Modulates Wingless Signaling in Drosophila Embryos , 2001, Cell.
[72] N. Perrimon,et al. Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. , 2001, Development.
[73] Marino Zerial,et al. Rab proteins as membrane organizers , 2001, Nature Reviews Molecular Cell Biology.
[74] R. Moon,et al. The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape. , 2000, Trends in genetics : TIG.
[75] M. Bernfield,et al. Syndecan-1 is required for Wnt-1-induced mammary tumorigenesis in mice , 2000, Nature Genetics.
[76] M. Vidal,et al. Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling. , 2007, Developmental cell.
[77] R. Nusse,et al. BMC Cell Biology BioMed Central Research article , 2006 .
[78] P. Bodine,et al. The orphan receptor tyrosine kinase Ror2 modulates canonical Wnt signaling in osteoblastic cells. , 2005, Molecular endocrinology.
[79] L. Malerød,et al. Clathrin-dependent endocytosis. , 2004, The Biochemical journal.