Biglycan stimulates VEGF expression in endothelial cells by activating the TLR signaling pathway

[1]  M. Sohrabi,et al.  Gastric Cancer and Helicobacter pylori: Impact of hopQII Gene. , 2016, Cellular and molecular biology.

[2]  Wei Zhao,et al.  Helicobacter pylori CagA induces tumor suppressor gene hypermethylation by upregulating DNMT1 via AKT-NFκB pathway in gastric cancer development , 2016, Oncotarget.

[3]  Xiaohu Gu,et al.  Biglycan up-regulated vascular endothelial growth factor (VEGF) expression and promoted angiogenesis in colon cancer , 2015, Tumor Biology.

[4]  R. Iozzo,et al.  Soluble biglycan as a biomarker of inflammatory renal diseases. , 2014, The international journal of biochemistry & cell biology.

[5]  Jiping Zeng,et al.  Histone demethylase RBP2 induced by Helicobactor Pylori CagA participates in the malignant transformation of gastric epithelial cells , 2014, Oncotarget.

[6]  R. Iozzo,et al.  De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways. , 2014, Matrix biology : journal of the International Society for Matrix Biology.

[7]  J. Pfeilschifter,et al.  Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury. , 2014, Matrix biology : journal of the International Society for Matrix Biology.

[8]  Bingya Liu,et al.  Biglycan enhances gastric cancer invasion by activating FAK signaling pathway , 2014, Oncotarget.

[9]  T. Zeng,et al.  High expression of biglycan is associated with poor prognosis in patients with esophageal squamous cell carcinoma. , 2013, International journal of clinical and experimental pathology.

[10]  M. Blanca Piazuelo,et al.  Gastric cáncer: Overview , 2013, Colombia medica.

[11]  M. T. Moser,et al.  Peroxiredoxin 1 Stimulates Endothelial Cell Expression of VEGF via TLR4 Dependent Activation of HIF-1α , 2012, PloS one.

[12]  N. Shinohara,et al.  Biglycan is a specific marker and an autocrine angiogenic factor of tumour endothelial cells , 2012, British Journal of Cancer.

[13]  I. Mackenzie,et al.  Cancer stem cells and EMT in carcinoma , 2012, Cancer and Metastasis Reviews.

[14]  M. Mikuła,et al.  Integrating proteomic and transcriptomic high-throughput surveys for search of new biomarkers of colon tumors , 2011, Functional & Integrative Genomics.

[15]  P. Allavena,et al.  Cancer-related inflammation , 2008, Nature.

[16]  K. Tsuneyama,et al.  Expressions of MMP-2, MMP-9 and VEGF are closely linked to growth, invasion, metastasis and angiogenesis of gastric carcinoma. , 2006, Anticancer research.

[17]  M. Karin.  Nuclear factor-κB in cancer development and progression , 2006, Nature.

[18]  L. Coussens,et al.  Tumor stroma and regulation of cancer development. , 2006, Annual review of pathology.

[19]  E. Kovacs,et al.  Aging negatively skews macrophage TLR2- and TLR4-mediated pro-inflammatory responses without affecting the IL-2-stimulated pathway , 2005, Mechanisms of Ageing and Development.

[20]  Marian F Young,et al.  The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. , 2005, The Journal of clinical investigation.

[21]  Xavier Matias-Guiu,et al.  NF-kB in development and progression of human cancer , 2005, Virchows Archiv.

[22]  P. Zigrino,et al.  Tumor-stroma interactions: their role in the control of tumor cell invasion. , 2005, Biochimie.

[23]  L. Bingle,et al.  In vitro study of HIF‐1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI‐3K/Akt and MEK1/ERK pathways , 2005, The Journal of pathology.

[24]  D. Golenbock,et al.  Activation of toll-like receptor (TLR)2, TLR4, and TLR9 in the mammalian cornea induces MyD88-dependent corneal inflammation. , 2005, Investigative ophthalmology & visual science.

[25]  E. F. Martinez,et al.  In vitro immunoexpression of extracellular matrix proteins in dental pulpal and gingival human fibroblasts. , 2004, International endodontic journal.

[26]  H. Yu,et al.  Overexpression of VEGF and Angiopoietin 2: A Key to High Vascularity of Hepatocellular Carcinoma? , 2003, Modern Pathology.

[27]  P. Ratcliffe,et al.  Regulation of angiogenesis by hypoxia: role of the HIF system , 2003, Nature Medicine.

[28]  T. Koga,et al.  BMRI in early detection of breast cancer in patients with increased genetic risk: our preliminary results. , 2002 .

[29]  T. Gress,et al.  Biglycan is overexpressed in pancreatic cancer and induces G1-arrest in pancreatic cancer cell lines. , 2001, Gastroenterology.

[30]  Thomas Hawighorst,et al.  Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis , 2001, Nature Medicine.

[31]  Takuma Sasaki,et al.  Role of vascular endothelial growth factor C expression in the development of lymph node metastasis in gastric cancer. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[32]  H. Joensuu,et al.  High pre‐treatment serum level of vascular endothelial growth factor (VEGF) is associated with poor outcome in small‐cell lung cancer , 1998, International journal of cancer.

[33]  A. Wetterwald,et al.  Expression of matrix proteins during the development of mineralized tissues. , 1996, Bone.

[34]  C. Vervaet,et al.  In-vivo evaluation of apocynin for prevention of Helicobacter pylori-induced gastric carcinogenesis , 2017, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

[35]  M. Simon,et al.  Hypoxia-inducible factors as essential regulators of inflammation. , 2010, Current topics in microbiology and immunology.

[36]  M. Karin.  Nuclear factor-kappaB in cancer development and progression. , 2006, Nature.

[37]  C. Xiao,et al.  NF-κB, an Evolutionarily Conserved Mediator of Immune and Inflammatory Responses , 2005 .

[38]  Jaw-Town Lin,et al.  Helicobacter pylori promote gastric cancer cells invasion through a NF-kappaB and COX-2-mediated pathway. , 2005, World journal of gastroenterology.

[39]  C. Xiao,et al.  NF-kappaB, an evolutionarily conserved mediator of immune and inflammatory responses. , 2005, Advances in experimental medicine and biology.

[40]  T. Koga,et al.  Clinical significance of vascular endothelial growth factor expression in gastric cancer. , 2002, Journal of experimental & clinical cancer research : CR.

[41]  T. Seufferlein,et al.  Transforming growth factor beta1 treatment leads to an epithelial-mesenchymal transdifferentiation of pancreatic cancer cells requiring extracellular signal-regulated kinase 2 activation. , 2001, Cancer research.

[42]  M. Zhao,et al.  Immunohistochemical and histochemical characterization of the mucosubstances of odontogenic myxoma: histogenesis and differential diagnosis. , 1999, Pathology, research and practice.

[43]  Y. Oshika,et al.  © 1998 Cancer Research Campaign , 2022 .