Technology related parameters affecting quantification in positron emission tomography imaging

Some of the issues associated with positron emission tomography (PET) technology which still pose challenges for the recovery of quantitative images are discussed. Through these issues reference to what is today considered as the ‘gold standard’ in quantitative PET imaging is also presented. A brief comparison of 2-D and 3-D PET is given, together with a short discussion of combined PET/CT imaging devices.

[1]  Gerald Antoch,et al.  Whole-body positron emission tomography-CT: optimized CT using oral and IV contrast materials. , 2002, AJR. American journal of roentgenology.

[2]  R. Wahl,et al.  PET/CT: comparison of quantitative tracer uptake between germanium and CT transmission attenuation-corrected images. , 2002, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[3]  D. Visvikis,et al.  CT-based attenuation correction in the calculation of semi-quantitative indices of [18F]FDG uptake in PET , 2003, European Journal of Nuclear Medicine and Molecular Imaging.

[4]  J. Ollinger Model-based scatter correction for fully 3D PET. , 1996, Physics in medicine and biology.

[5]  S R Cherry,et al.  3D PET using a conventional multislice tomograph without septa. , 1991, Journal of computer assisted tomography.

[6]  Carole Lartizien,et al.  A lesion detection observer study comparing 2-dimensional versus fully 3-dimensional whole-body PET imaging protocols. , 2004, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[7]  Habib Zaidi,et al.  Determination of the attenuation map in emission tomography. , 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[8]  Hall Wa,et al.  Quantification in clinical fluorodeoxyglucose positron emission tomography. , 2004 .

[9]  R. Wahl,et al.  Initial experience with oral contrast in PET/CT: phantom and clinical studies. , 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[10]  V J Cunningham,et al.  Quantification in positron emission tomography for research in pharmacology and drug development. , 2004, Nuclear medicine communications.

[11]  A. Lammertsma,et al.  Monitoring response to therapy in cancer using [18F]-2-fluoro-2-deoxy-d-glucose and positron emission tomography: an overview of different analytical methods , 2000, European Journal of Nuclear Medicine.

[12]  D. Visvikis,et al.  Influence of OSEM and segmented attenuation correction in the calculation of standardised uptake values for [18F]FDG PET , 2001, European Journal of Nuclear Medicine.

[13]  Cyrill Burger,et al.  PET-CT image co-registration in the thorax: influence of respiration , 2002, European Journal of Nuclear Medicine and Molecular Imaging.

[14]  Y. Erdi,et al.  FDG-PET standardized uptake values in normal anatomical structures using iterative reconstruction segmented attenuation correction and filtered back-projection , 2001, European Journal of Nuclear Medicine.

[15]  Wai-Hoi Wong,et al.  An analog decoding BGO block detector using circular photomultipliers , 1995 .

[16]  E. Hoffman,et al.  Measuring PET scanner sensitivity: relating countrates to image signal-to-noise ratios using noise equivalents counts , 1990 .

[17]  Paul Kinahan,et al.  Attenuation correction for a combined 3D PET/CT scanner. , 1998, Medical physics.

[18]  Tinsu Pan,et al.  Correction for oral contrast artifacts in CT attenuation-corrected PET images obtained by combined PET/CT. , 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[19]  M Schwaiger,et al.  Reproducibility of metabolic measurements in malignant tumors using FDG PET. , 1999, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[20]  Yuji Nakamoto,et al.  Respiratory motion artifacts on PET emission images obtained using CT attenuation correction on PET-CT , 2003, European Journal of Nuclear Medicine and Molecular Imaging.