Extraction techniques with deep eutectic solvents

Abstract In last years, a plethora of extraction techniques has emerged as environmental-friendly alternatives to conventional extraction procedures. In this particular field, a novel class of solvents known as deep eutectic solvents (DES) has arisen as a new and very promising tool. Compared with conventional organic solvents, DES as well as the so-called natural deep eutectic solvents (NADES) have attracted considerable attention due to the fact that they not only are eco-friendly, non-toxic, and biodegradable organic compounds but also have a low cost, being easy to produce in the own laboratory. The present review provides a critical and organized overview of novel extraction techniques using DES as extracting solvents that were applied in food, biological and environmental sample analysis. An evaluation of how these DES/NADES could improve extraction yields of a variety of analytes and advantages and limitations of each proposal will be discussed and compared with earlier studies.