Motor Cortex Is Required for Learning but Not for Executing a Motor Skill

[1]  K. S. Lashley,et al.  Studies of cerebral function in learning. XIII. Apparent absence of transcortical association in maze learning , 1944 .

[2]  K. S. Lashley,et al.  STUDIES OF CEREBRAL FUNCTION IN LEARNING: V. THE RETENTION OF MOTOR HABITS AFTER DESTRUCTION OF THE SO-CALLED MOTOR AREAS IN PRIMATES , 1924 .

[3]  D. G. Lawrence,et al.  The functional organization of the motor system in the monkey. I. The effects of bilateral pyramidal lesions. , 1968, Brain : a journal of neurology.

[4]  D. G. Lawrence,et al.  The functional organization of the motor system in the monkey. II. The effects of lesions of the descending brain-stem pathways. , 1968, Brain : a journal of neurology.

[5]  A. Castro,et al.  The effects of cortical ablations on digital usage in the rat. , 1972, Brain research.

[6]  M. Ioffe Pyramidal influences in establishment of new motor coordinations in dogs. , 1973, Physiology & behavior.

[7]  Ioffe Me Pyramidal influences in establishment of new motor coordinations in dogs , 1973 .

[8]  D. G. Lawrence,et al.  The development of motor control in the rhesus monkey: evidence concerning the role of corticomotoneuronal connections. , 1976, Brain : a journal of neurology.

[9]  Gary G. Berntson,et al.  Organization of brainstem behavioral systems , 1976, Brain Research Bulletin.

[10]  R. F. Thompson,et al.  The search for the engram. , 1976, The American psychologist.

[11]  V. Perry,et al.  The long-term effects of removal of sensorimotor cortex in infant and adult rhesus monkeys. , 1983, Brain : a journal of neurology.

[12]  C. Barnes,et al.  Brainstem control of spinal cord function , 1984 .

[13]  伊藤 正男 The cerebellum and neural control , 1984 .

[14]  A. Arnold,et al.  Forebrain lesions disrupt development but not maintenance of song in passerine birds. , 1984, Science.

[15]  G. Quirk,et al.  The organization of the rat motor cortex: A microstimulation mapping study , 1986, Brain Research Reviews.

[16]  I. Whishaw,et al.  The contributions of motor cortex, nigrostriatal dopamine and caudate-putamen to skilled forelimb use in the rat. , 1986, Brain : a journal of neurology.

[17]  O. I. Fukson,et al.  Adaptability of innate motor patterns and motor control mechanisms , 1986, Behavioral and Brain Sciences.

[18]  P. Killeen,et al.  A behavioral theory of timing. , 1988, Psychological review.

[19]  Jean Massion,et al.  Red nucleus: past and future , 1988, Behavioural Brain Research.

[20]  R. Nudo,et al.  Descending pathways to the spinal cord, III: Sites of origin of the corticospinal tract , 1990, The Journal of comparative neurology.

[21]  Ian Q. Whishaw,et al.  The impairments in reaching and the movements of compensation in rats with motor cortex lesions: an endpoint, videorecording, and movement notation analysis , 1991, Behavioural Brain Research.

[22]  D. Buxton,et al.  Origins and collateralization of corticospinal, corticopontine, corticorubral and corticostriatal tracts: a multiple retrograde fluorescent tracing study , 1992, Brain Research.

[23]  Lemon Rn,et al.  The G. L. Brown Prize Lecture. Cortical control of the primate hand , 1993 .

[24]  R N Lemon,et al.  The G. L. Brown Prize Lecture. Cortical control of the primate hand , 1993, Experimental physiology.

[25]  PL Strick,et al.  Corticospinal terminations in two new-world primates: further evidence that corticomotoneuronal connections provide part of the neural substrate for manual dexterity , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[26]  O. Hikosaka Role of Basal Ganglia in Control of Innate Movements, Learned Behavior and Cognition—A Hypothesis , 1994 .

[27]  A M Graybiel,et al.  The basal ganglia and adaptive motor control. , 1994, Science.

[28]  Leslie G. Ungerleider,et al.  Functional MRI evidence for adult motor cortex plasticity during motor skill learning , 1995, Nature.

[29]  P. Katz Neurons, Networks, and Motor Behavior , 1996, Neuron.

[30]  T. Drew,et al.  Role of the motor cortex in the control of visually triggered gait modifications. , 1996, Canadian journal of physiology and pharmacology.

[31]  J. Kleim,et al.  Functional reorganization of the rat motor cortex following motor skill learning. , 1998, Journal of neurophysiology.

[32]  D. Willingham A Neuropsychological Theory of Motor Skill Learning , 2004 .

[33]  M. Hallett,et al.  Rapid plasticity of human cortical movement representation induced by practice. , 1998, Journal of neurophysiology.

[34]  J. Donoghue,et al.  Strengthening of horizontal cortical connections following skill learning , 1998, Nature Neuroscience.

[35]  T. Schallert,et al.  Cortical injury impairs contralateral forelimb immobility during swimming: a simple test for loss of inhibitory motor control , 1999, Behavioural Brain Research.

[36]  H. Freund,et al.  The role of diaschisis in stroke recovery. , 1999, Stroke.

[37]  Eve Marder,et al.  Network Stability from Activity-Dependent Regulation of Neuronal Conductances , 1999, Neural Computation.

[38]  J. Donoghue,et al.  Plasticity and primary motor cortex. , 2000, Annual review of neuroscience.

[39]  Ian Q Whishaw,et al.  Loss of the innate cortical engram for action patterns used in skilled reaching and the development of behavioral compensation following motor cortex lesions in the rat , 2000, Neuropharmacology.

[40]  D. Wilkin,et al.  Neuron , 2001, Brain Research.

[41]  R. Nudo,et al.  Role of adaptive plasticity in recovery of function after damage to motor cortex , 2001, Muscle & nerve.

[42]  Kae Nakamura,et al.  Central mechanisms of motor skill learning , 2002, Current Opinion in Neurobiology.

[43]  Leslie G. Ungerleider,et al.  Imaging Brain Plasticity during Motor Skill Learning , 2002, Neurobiology of Learning and Memory.

[44]  Sten Grillner,et al.  Innate versus learned movements--a false dichotomy? , 2004, Progress in brain research.

[45]  Sabrina M. Tom,et al.  The Neural Correlates of Motor Skill Automaticity , 2005, The Journal of Neuroscience.

[46]  B. Woodside,et al.  Differential fos expression following aspiration, electrolytic, or excitotoxic lesions of the perirhinal cortex in rats. , 2005, Behavioral neuroscience.

[47]  J. Krakauer Motor learning: its relevance to stroke recovery and neurorehabilitation. , 2006, Current opinion in neurology.

[48]  I. Whishaw,et al.  Parallel stages of learning and recovery of skilled reaching after motor cortex stroke: “Oppositions” organize normal and compensatory movements , 2006, Behavioural Brain Research.

[49]  J. Kleim,et al.  Motor training induces experience-specific patterns of plasticity across motor cortex and spinal cord. , 2006, Journal of applied physiology.

[50]  Randolph J. Nudo,et al.  The Evolution of Motor Cortex and Motor Systems , 2007 .

[51]  A. Luft,et al.  Stages of motor skill learning , 2005, Molecular Neurobiology.

[52]  I. Whishaw,et al.  Motor cortex stroke impairs individual digit movement in skilled reaching by the rat , 2008, The European journal of neuroscience.

[53]  A. Graybiel Habits, rituals, and the evaluative brain. , 2008, Annual review of neuroscience.

[54]  J. Kalaska,et al.  Muscle synergies during locomotion in the cat: a model for motor cortex control , 2008, The Journal of physiology.

[55]  R. Lemon Descending pathways in motor control. , 2008, Annual review of neuroscience.

[56]  Willie F. Tobin,et al.  Rapid formation and selective stabilization of synapses for enduring motor memories , 2009, Nature.

[57]  D. Lovinger,et al.  Dynamic reorganization of striatal circuits during the acquisition and consolidation of a skill , 2009, Nature Neuroscience.

[58]  J. Doyon,et al.  Contributions of the basal ganglia and functionally related brain structures to motor learning , 2009, Behavioural Brain Research.

[59]  Michale S Fee,et al.  A basal ganglia-forebrain circuit in the songbird biases motor output to avoid vocal errors , 2009, Proceedings of the National Academy of Sciences.

[60]  Jennifer C. Romano,et al.  One-year retention of general and sequence-specific skills in a probabilistic, serial reaction time task , 2010, Memory.

[61]  A. Graybiel,et al.  Differential Dynamics of Activity Changes in Dorsolateral and Dorsomedial Striatal Loops during Learning , 2010, Neuron.

[62]  M. Desmurget,et al.  Basal ganglia contributions to motor control: a vigorous tutor , 2010, Current Opinion in Neurobiology.

[63]  Stuart N Baker,et al.  The primate reticulospinal tract, hand function and functional recovery , 2011, The Journal of physiology.

[64]  Bence P Ölveczky,et al.  Motoring ahead with rodents , 2011, Current Opinion in Neurobiology.

[65]  Ling Wang,et al.  Structural plasticity within highly specific neuronal populations identifies a unique parcellation of motor learning in the adult brain , 2011, Proceedings of the National Academy of Sciences.

[66]  J. Krakauer,et al.  Are We Ready for a Natural History of Motor Learning? , 2011, Neuron.

[67]  Jeffrey C. Erlich,et al.  A Cortical Substrate for Memory-Guided Orienting in the Rat , 2011, Neuron.

[68]  John C Doyle,et al.  Architecture, constraints, and behavior , 2011, Proceedings of the National Academy of Sciences.

[69]  R. Morecraft,et al.  Functional recovery following motor cortex lesions in non-human primates: experimental implications for human stroke patients. , 2011, Journal of integrative neuroscience.

[70]  L. Cohen,et al.  Neuroplasticity Subserving Motor Skill Learning , 2011, Neuron.

[71]  J. Krakauer,et al.  How is a motor skill learned? Change and invariance at the levels of task success and trajectory control. , 2012, Journal of neurophysiology.

[72]  Stuart N. Baker,et al.  Changes in descending motor pathway connectivity after corticospinal tract lesion in macaque monkey , 2012, Brain : a journal of neurology.

[73]  Risa Kawai,et al.  A Fully Automated High-Throughput Training System for Rodents , 2013, PloS one.

[74]  Claire F. Honeycutt,et al.  Evidence for reticulospinal contributions to coordinated finger movements in humans. , 2013, Journal of neurophysiology.

[75]  Dagmar Sternad,et al.  Learning to never forget—time scales and specificity of long-term memory of a motor skill , 2013, Front. Comput. Neurosci..

[76]  Yoram Burak,et al.  The Basal Ganglia Is Necessary for Learning Spectral, but Not Temporal, Features of Birdsong , 2013, Neuron.

[77]  L. Bonazzi,et al.  Complex Movement Topography and Extrinsic Space Representation in the Rat Forelimb Motor Cortex as Defined by Long-Duration Intracortical Microstimulation , 2013, The Journal of Neuroscience.

[78]  Yohsuke R. Miyamoto,et al.  Temporal structure of motor variability is dynamically regulated and predicts motor learning ability , 2014, Nature Neuroscience.

[79]  Klaus-Peter Hoffmann,et al.  Arm Movements Induced by Electrical Microstimulation in the Superior Colliculus of the Macaque Monkey , 2014, The Journal of Neuroscience.

[80]  K. Branson,et al.  Behavioral Variability through Stochastic Choice and Its Gating by Anterior Cingulate Cortex , 2014, Cell.

[81]  Kris S Chaisanguanthum,et al.  Motor Variability Arises from a Slow Random Walk in Neural State , 2014, The Journal of Neuroscience.

[82]  Thomas M. Jessell,et al.  Skilled reaching relies on a V2a propriospinal internal copy circuit , 2014, Nature.

[83]  Silvia Arber,et al.  Brainstem nucleus MdV mediates skilled forelimb motor tasks , 2014, Nature.