Biochemical and functional studies on the regulation of the Saccharomyces cerevisiae AMPK homolog SNF1.

[1]  Zhi-Xin Wang,et al.  Structural insight into the autoinhibition mechanism of AMP-activated protein kinase , 2009, Nature.

[2]  B. Kemp,et al.  Thienopyridone drugs are selective activators of AMP-activated protein kinase beta1-containing complexes. , 2008, Chemistry & biology.

[3]  Yang Liu,et al.  Roles of the Glycogen-binding Domain and Snf4 in Glucose Inhibition of SNF1 Protein Kinase* , 2008, Journal of Biological Chemistry.

[4]  H. Mertens,et al.  Oligosaccharide recognition and binding to the carbohydrate binding module of AMP‐activated protein kinase , 2007, FEBS letters.

[5]  L. Shapiro,et al.  Structural insight into AMPK regulation: ADP comes into play. , 2007, Structure.

[6]  D. Hardie,et al.  AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy , 2007, Nature Reviews Molecular Cell Biology.

[7]  Liang Tong,et al.  Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1 , 2007, Nature.

[8]  David Carling,et al.  Structural basis for AMP binding to mammalian AMP-activated protein kinase , 2007, Nature.

[9]  A. Sharff,et al.  Structure of a CBS-domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP and ZMP. , 2007, Acta crystallographica. Section D, Biological crystallography.

[10]  Lawrence Shapiro,et al.  Crystal Structures of the Adenylate Sensor from Fission Yeast AMP-Activated Protein Kinase , 2007, Science.

[11]  Tao Pang,et al.  Conserved α-Helix Acts as Autoinhibitory Sequence in AMP-activated Protein Kinase α Subunits* , 2007, Journal of Biological Chemistry.

[12]  L. Tong,et al.  Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding. , 2007, Structure.

[13]  V. Nayak Structure and dimerization of the kinase domain from yeast Snf1 , 2006 .

[14]  S. Berger,et al.  Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family. , 2006, Structure.

[15]  L. Tong,et al.  Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1. , 2005, Biochemical and biophysical research communications.

[16]  Galina Polekhina,et al.  Structural basis for glycogen recognition by AMP-activated protein kinase. , 2005, Structure.

[17]  B. Kemp,et al.  AMP-activated Protein Kinase β Subunit Tethers α and γ Subunits via Its C-terminal Sequence (186–270)* , 2005, Journal of Biological Chemistry.

[18]  D. Hardie,et al.  AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. , 2005, Cell metabolism.

[19]  M. Carlson,et al.  Pak1 Protein Kinase Regulates Activation and Nuclear Localization of Snf1-Gal83 Protein Kinase , 2004, Molecular and Cellular Biology.

[20]  B. Kemp Bateman domains and adenosine derivatives form a binding contract. , 2004, The Journal of clinical investigation.

[21]  D. Hardie,et al.  CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations. , 2004, The Journal of clinical investigation.

[22]  B. Kemp,et al.  AMPK β Subunit Targets Metabolic Stress Sensing to Glycogen , 2003, Current Biology.

[23]  J. James,et al.  A Novel Domain in AMP-Activated Protein Kinase Causes Glycogen Storage Bodies Similar to Those Seen in Hereditary Cardiac Arrhythmias , 2003, Current Biology.

[24]  R. McCartney,et al.  Isolation of Mutations in the Catalytic Domain of the Snf1 Kinase That Render Its Activity Independent of the Snf4 Subunit , 2003, Eukaryotic Cell.

[25]  D J Campbell,et al.  AMP-activated protein kinase, super metabolic regulator. , 2001, Biochemical Society transactions.

[26]  P. Sanz Snf1 protein kinase: a key player in the response to cellular stress in yeast. , 2001, Biochemical Society transactions.

[27]  B. Kemp,et al.  AMPK beta subunit targets metabolic stress sensing to glycogen. , 2003, Current biology : CB.

[28]  B. Kemp,et al.  Functional Domains of the α1 Catalytic Subunit of the AMP-activated Protein Kinase* , 1998, The Journal of Biological Chemistry.

[29]  M. Carlson,et al.  The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? , 1998, Annual review of biochemistry.

[30]  C. Fisher,et al.  Modification of a PCR-based site-directed mutagenesis method. , 1997, BioTechniques.

[31]  M. Carlson,et al.  The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex , 1997, Molecular and cellular biology.

[32]  A. Bateman The structure of a domain common to archaebacteria and the homocystinuria disease protein. , 1997, Trends in biochemical sciences.

[33]  M. Carlson,et al.  Glucose regulates protein interactions within the yeast SNF1 protein kinase complex. , 1996, Genes & development.

[34]  J. Scott,et al.  Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo. , 1994, The Journal of biological chemistry.

[35]  M. Carlson,et al.  Mutational analysis of the Saccharomyces cerevisiae SNF1 protein kinase and evidence for functional interaction with the SNF4 protein , 1989, Molecular and cellular biology.

[36]  M. Carlson,et al.  A yeast gene that is essential for release from glucose repression encodes a protein kinase. , 1986, Science.