All-human microphysical model of metastasis therapy

[1]  D. Lauffenburger,et al.  All-human microphysical model of metastasis therapy , 2013, Stem cell research & therapeutics.

[2]  Andrej J. Savol,et al.  Modeling Boundary Conditions for Balanced Proliferation in Metastatic Latency , 2013, Clinical Cancer Research.

[3]  R. Stevens,et al.  Case-control study of shift-work and breast cancer risk in Danish nurses: impact of shift systems. , 2012, European journal of cancer.

[4]  Shuichi Takayama,et al.  384 hanging drop arrays give excellent Z‐factors and allow versatile formation of co‐culture spheroids , 2012, Biotechnology and bioengineering.

[5]  Vito Pistoia,et al.  Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy , 2012, Science Translational Medicine.

[6]  A. Loudon,et al.  The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines , 2011, Proceedings of the National Academy of Sciences.

[7]  Jiandie D. Lin,et al.  Temporal orchestration of circadian autophagy rhythm by C/EBPβ , 2011, The EMBO journal.

[8]  Franziska Hirschhaeuser,et al.  Lactate: a metabolic key player in cancer. , 2011, Cancer research.

[9]  A. Atwood,et al.  Cell-autonomous circadian clock of hepatocytes drives rhythms in transcription and polyamine synthesis , 2011, Proceedings of the National Academy of Sciences.

[10]  Niraj K Inamdar,et al.  Microfluidic cell culture models for tissue engineering. , 2011, Current opinion in biotechnology.

[11]  Paul A. Khavari,et al.  Invasive 3-Dimensional Organotypic Neoplasia from Multiple Normal Human Epithelia , 2010, Nature Medicine.

[12]  Karen L. Gamble,et al.  Dysregulation of Inflammatory Responses by Chronic Circadian Disruption , 2010, The Journal of Immunology.

[13]  D. Bechtold,et al.  Circadian dysfunction in disease. , 2010, Trends in pharmacological sciences.

[14]  S. Panda,et al.  AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation , 2009, Science.

[15]  Pamela K. Kreeger,et al.  Cancer systems biology: a network modeling perspective , 2009, Carcinogenesis.

[16]  Walker Inman,et al.  Liver tissue engineering in the evaluation of drug safety , 2009, Expert opinion on drug metabolism & toxicology.

[17]  David J Beebe,et al.  Cellular observations enabled by microculture: paracrine signaling and population demographics. , 2009, Integrative biology : quantitative biosciences from nano to macro.

[18]  A. Wells,et al.  E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas , 2008, Clinical & Experimental Metastasis.

[19]  Julio Saez-Rodriguez,et al.  Fuzzy Logic Analysis of Kinase Pathway Crosstalk in TNF/EGF/Insulin-Induced Signaling , 2007, PLoS Comput. Biol..

[20]  J. Aguirre-Ghiso,et al.  Models, mechanisms and clinical evidence for cancer dormancy , 2007, Nature Reviews Cancer.

[21]  Daniel A Fletcher,et al.  Tissue Geometry Determines Sites of Mammary Branching Morphogenesis in Organotypic Cultures , 2006, Science.

[22]  Trey Ideker,et al.  Bioengineering and Systems Biology , 2006, Annals of Biomedical Engineering.

[23]  D. Lauffenburger,et al.  A Systems Model of Signaling Identifies a Molecular Basis Set for Cytokine-Induced Apoptosis , 2005, Science.

[24]  J. Brugge,et al.  Use of Three-Dimensional Basement Membrane Cultures to Model Oncogene-Induced Changes in Mammary Epithelial Morphogenesis , 2004, Journal of Mammary Gland Biology and Neoplasia.

[25]  G. Naumov,et al.  Persistence of solitary mammary carcinoma cells in a secondary site: a possible contributor to dormancy. , 2002, Cancer research.

[26]  I. Macdonald,et al.  Temporal progression of metastasis in lung: cell survival, dormancy, and location dependence of metastatic inefficiency. , 2000, Cancer research.

[27]  K. Luzzi,et al.  Multistep nature of metastatic inefficiency: dormancy of solitary cells after successful extravasation and limited survival of early micrometastases. , 1998, The American journal of pathology.

[28]  A. Wells,et al.  Hepatocyte induced re-expression of E-cadherin in breast and prostate cancer cells increases chemoresistance , 2011, Clinical & Experimental Metastasis.

[29]  Alan Wells,et al.  Novel three-dimensional organotypic liver bioreactor to directly visualize early events in metastatic progression. , 2007, Advances in cancer research.

[30]  S. Ohdo.  Circadian rhythms in the CNS and peripheral clock disorders: chronopharmacological findings on antitumor drugs. , 2007, Journal of pharmacological sciences.

[31]  G. Hortobagyi,et al.  Overview of resistance to systemic therapy in patients with breast cancer. , 2007, Advances in experimental medicine and biology.