Simulating the Spread of Membrane Potential Changes in Arteriolar Networks

Objective: Our aim was to simulate the spread of membrane potential changes in microvascular trees and then make the simulation programs accessible to other researchers. We have applied our simulations to demonstrate the implications of electrical coupling between arteriolar smooth muscle and endothelium.

[1]  D. Welsh,et al.  Spread of vasodilatation and vasoconstriction along feed arteries and arterioles of hamster skeletal muscle , 1999, The Journal of physiology.

[2]  C. Guibert,et al.  Positive and negative coupling of the endothelin ETA receptor to Ca2+‐permeable channels in rabbit cerebral cortex arterioles , 1999, The Journal of physiology.

[3]  K. Endlich,et al.  Electrically induced vasomotor responses and their propagation in rat renal vessels In vivo , 1997, The Journal of physiology.

[4]  F. Edwards,et al.  Electrical properties of iridial arterioles of the rat. , 1997, American journal of physiology. Heart and circulatory physiology.

[5]  M. Hines,et al.  The NEURON Simulation Environment , 1997, Neural Computation.

[6]  N. Holstein-Rathlou,et al.  Internephron coupling by conducted vasomotor responses in normotensive and spontaneously hypertensive rats. , 1997, The American journal of physiology.

[7]  L. Moore,et al.  Branching patterns and autoregulatory responses of juxtamedullary afferent arterioles. , 1997, The American journal of physiology.

[8]  B. Duling,et al.  Morphology favors an endothelial cell pathway for longitudinal conduction within arterioles. , 1997, Microvascular research.

[9]  T. Neild,et al.  Conducted depolarization in arteriole networks of the guinea‐pig small intestine: effect of branching of signal dissipation. , 1996, The Journal of physiology.

[10]  O. Schaad,et al.  Electrotonic propagation of kinin-induced, endothelium-dependent hyperpolarizations in pig coronary smooth muscles. , 1996, Journal of vascular research.

[11]  J. Lash Regulation of Skeletal Muscle Blood Flow During Contractions , 1996, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[12]  B. Duling,et al.  Electromechanical coupling and the conducted vasomotor response. , 1995, The American journal of physiology.

[13]  S. Segal,et al.  Cell-to-cell communication coordinates blood flow control. , 1994, Hypertension.

[14]  D. Grant,et al.  Electrophysiological characteristics of cultured human umbilical vein endothelial cells. , 1994, Microvascular research.

[15]  B. Duling,et al.  Heterogeneity in conducted arteriolar vasomotor response is agonist dependent. , 1991, The American journal of physiology.

[16]  M Hines,et al.  A program for simulation of nerve equations with branching geometries. , 1989, International journal of bio-medical computing.

[17]  J. Daut,et al.  Passive electrical properties and electrogenic sodium transport of cultured guinea‐pig coronary endothelial cells. , 1988, The Journal of physiology.

[18]  T. Neild The relation between the structure and innervation of small arteries and arterioles and the smooth muscle membrane potential changes expected at different levels of sympathetic nerve activity , 1983, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[19]  J. E. Mann,et al.  Propagation Down a Chain of Excitable Cells by Electric Field Interactions in the Junctional Clefts: Effect of Variation in Extracellular Resistances, Including a "Sucrose Gap" Simulation , 1983, IEEE Transactions on Biomedical Engineering.

[20]  B. Duling,et al.  Quantitative morphology of arterioles from the hamster cheek pouch related to mechanical analysis. , 1982, Microvascular research.

[21]  G. Hirst,et al.  An analysis of excitatory junctional potentials recorded from arterioles. , 1978, The Journal of physiology.

[22]  M. Bennett Autonomic neuromuscular transmission. , 1973, Monographs of the Physiological Society.

[23]  J J Jack,et al.  The propagation of transient potentials in some linear cable structures , 1971, The Journal of physiology.

[24]  T. Tomita,et al.  Cable properties of smooth muscle , 1968, The Journal of physiology.

[25]  J. Rhodin,et al.  The ultrastructure of mammalian arterioles and precapillary sphincters. , 1967, Journal of ultrastructure research.

[26]  Donald G Welsh,et al.  Endothelial and smooth muscle cell conduction in arterioles controlling blood flow. , 1998, American journal of physiology. Heart and circulatory physiology.

[27]  B. Cragg,et al.  Measurements of smooth muscle cells in arterioles of guinea pig ileum. , 1980, Acta anatomica.

[28]  Johannes A. G. Rhodin,et al.  Architecture of the Vessel Wall , 1980 .