An approach to control of bioreactors. Application of the gain–scheduling method

A control system based on a combination of the gain-scheduling control method and an adaptive PID controller was designed for the production of xylose from hardwood hemicellulose using a stirring tank reactor. Different operating conditions have been considered for estimating the adjustable parameter (θ) to take into account the changes of energy of the system. The performance of the control system was studied first by numerical simulation, and after implementation in the stirred tank reactor where the controller actually works.