Facile synthesis of α-fluoro substituted amidines from imidoyl chlorides and some of its application

[1]  Min Zhang,et al.  Facile synthesis of fluorinated α-imino alkynes by the coupling reaction of imidoyl iodides with terminal alkynes , 2006 .

[2]  Yong-ming Wu,et al.  The chemical transformation of β-bromodifluoromethyl β-enaminoketones: Synthesis of difluoromethylene thioether compounds , 2006 .

[3]  F. Rominger,et al.  Concise syntheses of meridianins by carbonylative alkynylation and a four-component pyrimidine synthesis. , 2005, Angewandte Chemie.

[4]  Yong-ming Wu,et al.  β-Bromodifluoromethyl β-enaminoketones: versatile synthetic intermediates for synthesis of CF2-containing compounds , 2005 .

[5]  N. Meanwell,et al.  Synthesis of substituted aryl amidines from aminoacetonitriles , 2005 .

[6]  J. Cesar.  Solid-phase synthesis of structurally diverse 2-alkyl- and 2-aryl-pyrimidines from support-bound amidines. , 2005, Journal of combinatorial chemistry.

[7]  P. Dunn.  Amidines and N -Substituted Amidines , 2005 .

[8]  Yong-ming Wu,et al.  One-pot synthesis of bromodifluoroacetimidoyl halides and its Suzuki coupling reactions with aryl boronic acids , 2005 .

[9]  Y. Matsumoto,et al.  Orally active factor Xa inhibitor: synthesis and biological activity of masked amidines as prodrugs of novel 1,4-diazepane derivatives. , 2004, Bioorganic & medicinal chemistry.

[10]  B. Stanovnik,et al.  Application of alkyl 3-dimethylamino-2-(1H-indol-3-yl)propenoates in the synthesis of 3-heteroarylindoles , 2004 .

[11]  M. Maccoss,et al.  Amidines as amide bond replacements in VLA-4 antagonists. , 2004, Bioorganic & medicinal chemistry letters.

[12]  A. Contini,et al.  3‐Nitrocoumarin Amidines: A New Synthetic Strategy for Substituted [1]Benzopyrano[3,4‐d]imidazol‐4(3H)‐ones , 2003 .

[13]  Min Zhang,et al.  Synthesis of 4-trifluoromethylpyrido[1,2-a)pyrimidin-2-ones utilizing activated alkynoates , 2003 .

[14]  M. Bagley,et al.  Highly efficient synthesis of pyrimidines under microwave-assisted conditions , 2003 .

[15]  R. Hank,et al.  An Optimized Process for Formation of 2,4-Disubstituted Imidazoles from Condensation of Amidines and α-Haloketones , 2002 .

[16]  I. Ashworth,et al.  An asymmetric synthesis of a 4-substituted-1,4-dihydropyridine , 2002 .

[17]  K. Okuda,et al.  Polycyclic N-Heterocyclic Compounds. 56 Reaction of N-(5,6-Dihydro[1]benzoxepino[5,4-d]pyrimidin-4-yl)amidine or Its Amide Oxime Derivatives with Hydroxylamine Hyrdochloride† , 2001 .

[18]  V. Puranik,et al.  Facile Synthesis of 4-Acylamino and 4-Sulphonamido β-lactams , 2000 .

[19]  A. Kraft.  Branched non-covalent complexes between carboxylic acids and two tris(amidines) , 1999 .

[20]  W. Bode,et al.  Design of benzamidine-type inhibitors of factor Xa. , 1998, Journal of medicinal chemistry.

[21]  S. Banba,et al.  New platelet fibrinogen receptor glycoprotein IIb-IIIa antagonists: orally active series of N-alkylated amidines with a 6,6-bicyclic template. , 1998, Journal of medicinal chemistry.

[22]  U Winkler,et al.  Synthesis and evaluation of diphenyl phosphonate esters as inhibitors of the trypsin-like granzymes A and K and mast cell tryptase. , 1998, Journal of medicinal chemistry.

[23]  R. Boere,et al.  Synthesis of some very bulky N,N′-disubstituted amidines and initial studies of their coordination chemistry† , 1998 .

[24]  A. Yudin,et al.  Perfluoroalkylation with Organosilicon Reagents. , 1997, Chemical reviews.

[25]  W. DeGrado,et al.  Design, synthesis, and in vitro activities of benzamide-core glycoprotein IIb/IIIa antagonists: 2,3-diaminopropionic acid derivatives as surrogates of aspartic acid. , 1997, Bioorganic & medicinal chemistry.

[26]  B Kohl,et al.  From peptide to non-peptide. 3. Atropisomeric GPIIbIIIa antagonists containing the 3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione nucleus. , 1997, Journal of medicinal chemistry.

[27]  B. Smart,et al.  Organofluorine chemistry : principles and commercial applications , 1994 .

[28]  G. Boyd.  Recent Advances in the Synthesis of Amidines , 1992 .

[29]  G. Boyd.  Reactions and Synthetic Uses of Amidines , 1992 .

[30]  M. Dräger,et al.  Synthesis, configuration, and calcium modulatory properties of enantiomerically pure 5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylates. , 1992, Journal of medicinal chemistry.

[31]  T. Kitazume,et al.  Antibody-catalyzed double stereoselection in fluorinated materials , 1991 .

[32]  John T. Welch,et al.  Fluorine in bioorganic chemistry , 1991 .

[33]  S. Patai.  The Chemistry of amidines and imidates , 1975 .