Studies on allogeneic inhibition I. Differential behavior of mouse tumors transplanted to homozygous and F1 hybrid hosts

Lymphomas, carcinomas and sarcomas originating in homozygous hosts grew better when transplanted into syngeneic mice than in F1 hybrids between the syngeneic and an allogeneic strain. The growth inhibition in F1 hybrids was called allogeneic inhibition. In order to demonstrate the phenomenon small inocula had to be used, as a rule below 106 cells. It was demonstrated with tumors originating in seven different mouse strains tested (A, A.SW, A.CA, A.BY, C57BL, C57L and C3H).

[1]  K. Hellström,et al.  Studies on allogeneic inhibition II. Inhibition of mouse tumor cell growth by In vitro contact with cells containing foreign H‐2 antigens , 1966 .

[2]  K. Hellström,et al.  Allogeneic Inhibition of Tumour Cells by in vitro Contact with Cells Containing Foreign H-2 Antigens , 1965, Nature.

[3]  K. Hellström,et al.  Immunological and Immunogenetic Aspects of Tumor Transplantation (Part 1 of 3) , 1965 .

[4]  R. Huemer.  Repression of Growth, and Subsequent Adaptation, of A Parental Strain Tumour in Genetically Compatible F1 Hybrid Mice , 1965, Nature.

[5]  K. Hellström,et al.  Demonstration of Syngeneic Preference In Vitro , 1964, Nature.

[6]  G. Cudkowicz,et al.  DEFICIENT GROWTH OF C57BL MARROW CELLS TRANSPLANTED IN F1 HYBRID MICE. ASSOCIATION WITH THE HISTOCOMPATIBILITY-2 LOCUS. , 1964, Immunology.

[7]  K. Hellstroem.  GROWTH INHIBITION OF SARCOMA AND CARCINOMA CELLS OF HOMOZYGOUS ORIGIN. , 1964, Science.

[8]  K. Hellström.  Differential Behaviour of Transplanted Mouse Lymphoma Lines in Genetically Compatible Homozygous and F1 Hybrid Mice , 1963, Nature.

[9]  J. Batchelor,et al.  SEROLOGICAL STUDIES ON THE X ANTIGENS * , 1962 .

[10]  F. Celada,et al.  DEMONSTRATION OF F1 HYBRID ANTI-PARENT IMMUNOLOGICAL REACTION , 1962 .

[11]  K. Hellström.  Studies on the mechanism of isoantigenic variant formation in heterozygous mouse tumors. II. Behavior of H-2 antigens D and K: cytotoxic tests on mouse lymphomas. , 1961 .

[12]  G. Snell,et al.  Histocompatibility genes of mice. III. H-1 and H-4, two histocompatibility loci in the first linkage group. , 1961, Immunology.

[13]  G. Cudkowicz.  Evidence for Immunization of F1 Hybrid Mice Against Parental Transplantation Antigens , 1961 .

[14]  G. Snell.  Note on results of Linder and Klein with coisogenic resistant lines of mice. , 1960 .

[15]  E. Klein,et al.  Skin and tumor grafting in coisogenic resistant lines of mice and their hybrids. , 1960, Journal of the National Cancer Institute.

[16]  G. Snell,et al.  Histocompatibility genes of the mouse. II. Production and analysis of isogenic resistant lines. , 1958, Journal of the National Cancer Institute.

[17]  G. Snell.  The genetics of transplantation. , 1953, Annals of the New York Academy of Sciences.

[18]  L. Cohen,et al.  Radiobiology of the C3H Mouse Mammary Carcinoma: Effect of Immunogenetic Factors on the Radiosensitivity of the Tumour Treated In Situ , 1954, British Journal of Cancer.

[19]  C. Little.  The genetics of tumor transplantation. , 1941 .