The role of the wnt/β-catenin signaling pathway in formation and maintenance of bone and teeth.
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[1] Mark L. Johnson,et al. Beta-Catenin Haplo Insufficient Male Mice Do Not Lose Bone in Response to Hindlimb Unloading , 2016, PloS one.
[2] P. Newsholme,et al. Multi-lineage differentiation of mesenchymal stem cells - To Wnt, or not Wnt. , 2015, The international journal of biochemistry & cell biology.
[3] B. Clarke,et al. Bone biology, signaling pathways, and therapeutic targets for osteoporosis. , 2015, Maturitas.
[4] D. E. Gibbons,et al. Dynamic fluid flow induced mechanobiological modulation of in situ osteocyte calcium oscillations. , 2015, Archives of biochemistry and biophysics.
[5] P. Esbrit,et al. VEGF Receptor 2 (VEGFR2) Activation Is Essential for Osteocyte Survival Induced by Mechanotransduction , 2015, Journal of cellular physiology.
[6] D. Burr,et al. Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone , 2015, Proceedings of the National Academy of Sciences.
[7] J. Helms,et al. Wnt signaling regulates homeostasis of the periodontal ligament. , 2014, Journal of periodontal research.
[8] M. Capulli,et al. Osteoblast and osteocyte: games without frontiers. , 2014, Archives of biochemistry and biophysics.
[9] R. Weinstein,et al. Osteocyte-derived RANKL is a critical mediator of the increased bone resorption caused by dietary calcium deficiency. , 2014, Bone.
[10] G. Livshits,et al. Osteocyte control of bone remodeling: is sclerostin a key molecular coordinator of the balanced bone resorption–formation cycles? , 2014, Osteoporosis International.
[11] B. Clarke,et al. Anti-sclerostin antibodies: utility in treatment of osteoporosis. , 2014, Maturitas.
[12] G. Papaccio,et al. Bone defects: molecular and cellular therapeutic targets. , 2014, The international journal of biochemistry & cell biology.
[13] P. D’Haese,et al. Romosozumab in postmenopausal women with osteopenia. , 2014, The New England journal of medicine.
[14] Mark L. Johnson,et al. Deletion of a Single β‐Catenin Allele in Osteocytes Abolishes the Bone Anabolic Response to Loading , 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[15] T. Komori. Mouse Models for the Evaluation of Osteocyte Functions , 2014, Journal of bone metabolism.
[16] Cesar Libanati,et al. Romosozumab in postmenopausal women with low bone mineral density , 2014, The New England journal of medicine.
[17] R. Rabadán,et al. Leukemogenesis Induced by an Activating β-catenin mutation in Osteoblasts , 2014, Nature.
[18] S. Premaraj,et al. Focal adhesion kinase mediates β-catenin signaling in periodontal ligament cells. , 2013, Biochemical and biophysical research communications.
[19] E. Canalis. Wnt signalling in osteoporosis: mechanisms and novel therapeutic approaches , 2013, Nature Reviews Endocrinology.
[20] Bo Zhang,et al. Effects of Constitutive β-Catenin Activation on Vertebral Bone Growth and Remodeling at Different Postnatal Stages in Mice , 2013, PloS one.
[21] Ivo Kalajzic,et al. In vitro and in vivo approaches to study osteocyte biology. , 2013, Bone.
[22] L. Bonewald,et al. Preface: the osteocyte. , 2013, Bone.
[23] B. Williams,et al. Regulation of Wnt/β-catenin signaling within and from osteocytes. , 2013, Bone.
[24] Sarah L Dallas,et al. The osteocyte: an endocrine cell ... and more. , 2013, Endocrine reviews.
[25] L. Bonewald,et al. FGF23 production by osteocytes , 2013, Pediatric Nephrology.
[26] J. Xie,et al. Disruption of Wnt/β-catenin Signaling in Odontoblasts and Cementoblasts Arrests Tooth Root Development in Postnatal Mouse Teeth , 2013, International journal of biological sciences.
[27] M. Amling,et al. Canonical Wnt signaling inhibits osteoclastogenesis independent of osteoprotegerin , 2013, The Journal of cell biology.
[28] M. Martín-Millán,et al. Crosstalk between Caveolin-1/Extracellular Signal-regulated Kinase (ERK) and β-Catenin Survival Pathways in Osteocyte Mechanotransduction* , 2013, The Journal of Biological Chemistry.
[29] E. Cho,et al. β-catenin is Required in Odontoblasts for Tooth Root Formation , 2013, Journal of dental research.
[30] S. Warren,et al. Flow perfusion maintains ex vivo bone viability: a novel model for bone biology research , 2012, Journal of tissue engineering and regenerative medicine.
[31] Mark L. Johnson,et al. Skeletal muscle secreted factors prevent glucocorticoid-induced osteocyte apoptosis through activation of β-catenin. , 2012, European cells & materials.
[32] D. Kiel,et al. Clinical review: Genome-wide association studies of skeletal phenotypes: what we have learned and where we are headed. , 2012, The Journal of clinical endocrinology and metabolism.
[33] Seung-O Ko,et al. Col1a1-cre mediated activation of β-catenin leads to aberrant dento-alveolar complex formation , 2012, Anatomy & cell biology.
[34] Konrad Basler,et al. The many faces and functions of β‐catenin , 2012, The EMBO journal.
[35] O. Kennedy,et al. Activation of resorption in fatigue-loaded bone involves both apoptosis and active pro-osteoclastogenic signaling by distinct osteocyte populations. , 2012, Bone.
[36] Lynda F. Bonewald,et al. Sclerostin Stimulates Osteocyte Support of Osteoclast Activity by a RANKL-Dependent Pathway , 2011, PloS one.
[37] X. Yang,et al. Constitutive stabilization of ß-catenin in the dental mesenchyme leads to excessive dentin and cementum formation. , 2011, Biochemical and biophysical research communications.
[38] Yan Jin,et al. High levels of β‐catenin signaling reduce osteogenic differentiation of stem cells in inflammatory microenvironments through inhibition of the noncanonical Wnt pathway , 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[39] S. Premaraj,et al. Mechanical loading activates β-catenin signaling in periodontal ligament cells. , 2011, The Angle orthodontist.
[40] L. Bonewald,et al. The Amazing Osteocyte , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[41] Mark L. Johnson,et al. Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone. , 2010, Bone.
[42] T. Bellido. Antagonistic interplay between mechanical forces and glucocorticoids in bone: A tale of kinases , 2010, Journal of cellular biochemistry.
[43] Hai Qing,et al. Mechanical Induction of PGE2 in Osteocytes Blocks Glucocorticoid-Induced Apoptosis Through Both the β-Catenin and PKA Pathways , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[44] Lynda F. Bonewald,et al. Osteocyte Wnt/β-Catenin Signaling Is Required for Normal Bone Homeostasis , 2010, Molecular and Cellular Biology.
[45] S. Millar,et al. Wnt/β-catenin Signaling in Oral Tissue Development and Disease , 2010, Journal of dental research.
[46] G. Luo,et al. A new osteopetrosis mutant mouse strain (ntl) with odontoma-like proliferations and lack of tooth roots. , 2009, European journal of oral sciences.
[47] Lynda F. Bonewald,et al. Prostaglandin Promotion of Osteocyte Gap Junction Function through Transcriptional Regulation of Connexin 43 by Glycogen Synthase Kinase 3/β-Catenin Signaling , 2009, Molecular and Cellular Biology.
[48] Y. Lan,et al. Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development. , 2009, Developmental biology.
[49] M. Bei. Molecular genetics of ameloblast cell lineage. , 2009, Journal of experimental zoology. Part B, Molecular and developmental evolution.
[50] E. Järvinen,et al. Tinkering with the inductive mesenchyme: Sostdc1 uncovers the role of dental mesenchyme in limiting tooth induction , 2009, Development.
[51] B. Clarke,et al. Normal bone anatomy and physiology. , 2008, Clinical journal of the American Society of Nephrology : CJASN.
[52] Katsu Takahashi,et al. Enhanced BMP signaling results in supernumerary tooth formation in USAG-1 deficient mouse. , 2008, Biochemical and biophysical research communications.
[53] Mark L. Johnson,et al. Osteocytes, mechanosensing and Wnt signaling. , 2008, Bone.
[54] M. Peifer,et al. Terminal regions of beta-catenin come into view. , 2008, Structure.
[55] Jie J. Zheng,et al. Crystal structure of a full-length beta-catenin. , 2008, Structure.
[56] Matthew R Allen,et al. Mechanical Stimulation of Bone in Vivo Reduces Osteocyte Expression of Sost/Sclerostin* , 2008, Journal of Biological Chemistry.
[57] Ron Y Kwon,et al. Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism , 2007, Proceedings of the National Academy of Sciences.
[58] B. Alman,et al. Beta-Catenin Signaling Plays a Disparate Role in Different Phases of Fracture Repair: Implications for Therapy to Improve Bone Healing , 2007, PLoS medicine.
[59] M. Seppala,et al. Hedgehog pathway gene expression during early development of the molar tooth root in the mouse. , 2007, Gene expression patterns : GEP.
[60] W. Birchmeier,et al. Continuous tooth generation in mouse is induced by activated epithelial Wnt/β-catenin signaling , 2006, Proceedings of the National Academy of Sciences.
[61] S. Fernandez,et al. Remodeling dynamics in the alveolar process in skeletally mature dogs. , 2006, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology.
[62] Hans Clevers,et al. Wnt/β-Catenin Signaling in Development and Disease , 2006, Cell.
[63] Mark L. Johnson,et al. Wnt/β-Catenin Signaling Is a Normal Physiological Response to Mechanical Loading in Bone* , 2006, Journal of Biological Chemistry.
[64] Stephen E. Harris,et al. E11/gp38 Selective Expression in Osteocytes: Regulation by Mechanical Strain and Role in Dendrite Elongation , 2006, Molecular and Cellular Biology.
[65] L. Bonewald. Summary--Osteocytes and mechanotransduction. , 2005, Journal of musculoskeletal & neuronal interactions.
[66] Bart O. Williams,et al. Essential Role of β-Catenin in Postnatal Bone Acquisition* , 2005, Journal of Biological Chemistry.
[67] Xizhi Guo,et al. Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. , 2005, Developmental cell.
[68] Hans Clevers,et al. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. , 2005, Developmental cell.
[69] D. Ornitz,et al. Sequential roles of Hedgehog and Wnt signaling in osteoblast development , 2004, Development.
[70] R. Nusse,et al. The Wnt signaling pathway in development and disease. , 2004, Annual review of cell and developmental biology.
[71] N. Perrimon,et al. The Promise and Perils of Wnt Signaling Through β-Catenin , 2002, Science.
[72] W. Birchmeier,et al. β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin , 2001, Cell.
[73] A. McMahon,et al. Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. , 2001, Development.
[74] S. Manolagas,et al. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. , 2000, Endocrine reviews.
[75] D L Lacey,et al. RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[76] Carmen Birchmeier,et al. Requirement for beta-catenin in anterior-posterior axis formation in mice. , 2000 .
[77] P. Roberson,et al. Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin. , 1999, The Journal of clinical investigation.
[78] M. Taketo,et al. Intestinal polyposis in mice with a dominant stable mutation of the β‐catenin gene , 1999, The EMBO journal.
[79] J. Wit,et al. The Role of Estrogen in the Control of Rat Osteocyte Apoptosis , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[80] Jörg Stappert,et al. β‐catenin is a target for the ubiquitin–proteasome pathway , 1997 .
[81] I. Thesleff,et al. Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development , 1993, Cell.
[82] C W Turck,et al. A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. , 1991, Science.
[83] R. Kemler,et al. The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. , 1989, The EMBO journal.
[84] Stefaan W Verbruggen,et al. Fluid flow in the osteocyte mechanical environment: a fluid–structure interaction approach , 2013, Biomechanics and Modeling in Mechanobiology.
[85] L. Bonewald,et al. Disruption of the insulin-like growth factor-1 gene in osteocytes impairs developmental bone growth in mice. , 2013, Bone.
[86] H. Deng,et al. Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts. , 2013, Bone.
[87] R. Atit,et al. Wnt/β-catenin signaling directs multiple stages of tooth morphogenesis , 2008 .
[88] G. Karsenty,et al. Molecular bases of the regulation of bone remodeling by the canonical Wnt signaling pathway. , 2006, Current topics in developmental biology.