Strategies for controlled delivery of growth factors and cells for bone regeneration.
暂无分享,去创建一个
[1] P. Layrolle,et al. Surface treatments of titanium dental implants for rapid osseointegration. , 2007, Dental materials : official publication of the Academy of Dental Materials.
[2] M. Kurabayashi,et al. Notch Signaling Induces Osteogenic Differentiation and Mineralization of Vascular Smooth Muscle Cells: Role of Msx2 Gene Induction via Notch-RBP-Jk Signaling , 2009, Arteriosclerosis, thrombosis, and vascular biology.
[3] Ulrich Joos,et al. VEGF-activated angiogenesis during bone regeneration. , 2005, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
[4] R. Gurny,et al. The effects of carrier nature and pH on rhBMP-2-induced ectopic bone formation. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[5] T. Clemens,et al. Mesenchymal stem cells expressing osteogenic and angiogenic factors synergistically enhance bone formation in a mouse model of segmental bone defect. , 2010, Molecular therapy : the journal of the American Society of Gene Therapy.
[6] G. Im,et al. Electroporation-mediated transfer of Runx2 and Osterix genes to enhance osteogenesis of adipose stem cells. , 2011, Biomaterials.
[7] Bin Wang,et al. Homogeneous osteogenesis and bone regeneration by demineralized bone matrix loading with collagen-targeting bone morphogenetic protein-2. , 2007, Biomaterials.
[8] E. Deutsch. The use of stem cell synthesized extracellular matrix for bone repair , 2009 .
[9] P. Kasten,et al. The effect of platelet-rich plasma on healing in critical-size long-bone defects. , 2008, Biomaterials.
[10] Chi-Hwa Wang,et al. Optimized bone regeneration based on sustained release from three‐dimensional fibrous PLGA/HAp composite scaffolds loaded with BMP‐2 , 2008, Biotechnology and bioengineering.
[11] David L. Kaplan,et al. Calcium phosphate combination biomaterials as human mesenchymal stem cell delivery vehicles for bone repair. , 2011, Journal of biomedical materials research. Part B, Applied biomaterials.
[12] Eva García,et al. Repair of rat mandibular bone defects by alveolar osteoblasts in a novel plasma-derived albumin scaffold. , 2010, Tissue engineering. Part A.
[13] K. Mustafa,et al. Endothelial cells influence the osteogenic potential of bone marrow stromal cells , 2009, Biomedical engineering online.
[14] L. Bonewald,et al. Signalling strategies for osteogenic differentiation of human umbilical cord mesenchymal stromal cells for 3D bone tissue engineering , 2009, Journal of tissue engineering and regenerative medicine.
[15] R. Guldberg,et al. Inducible regulation of Runx2-stimulated osteogenesis , 2006, Gene Therapy.
[16] Eben Alsberg,et al. Dual growth factor delivery and controlled scaffold degradation enhance in vivo bone formation by transplanted bone marrow stromal cells. , 2004, Bone.
[17] H. Redmond,et al. Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[18] S. Bryant,et al. Thermoresponsive, in situ cross-linkable hydrogels based on N-isopropylacrylamide: fabrication, characterization and mesenchymal stem cell encapsulation. , 2011, Acta biomaterialia.
[19] David L Kaplan,et al. Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering. , 2009, Journal of controlled release : official journal of the Controlled Release Society.
[20] Keun-Hong Park,et al. The use of injectable, thermosensitive poly(organophosphazene)-RGD conjugates for the enhancement of mesenchymal stem cell osteogenic differentiation. , 2009, Biomaterials.
[21] Tien-Min G. Chu,et al. Segmental bone regeneration using a load-bearing biodegradable carrier of bone morphogenetic protein-2. , 2007, Biomaterials.
[22] Fei Yang,et al. An injectable scaffold: rhBMP-2-loaded poly(lactide-co-glycolide)/hydroxyapatite composite microspheres. , 2010, Acta biomaterialia.
[23] Michael J Yaszemski,et al. Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration. , 2009, Biomaterials.
[24] Bin Chen,et al. The osteogenic effect of bone morphogenetic protein-2 on the collagen scaffold conjugated with antibodies. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[25] Hideki Yoshikawa,et al. Potentiation of the activity of bone morphogenetic protein-2 in bone regeneration by a PLA-PEG/hydroxyapatite composite. , 2005, Biomaterials.
[26] K. Neoh,et al. Titanium with surface-grafted dextran and immobilized bone morphogenetic protein-2 for inhibition of bacterial adhesion and enhancement of osteoblast functions. , 2009, Tissue engineering. Part A.
[27] R. Carano,et al. Angiogenesis and bone repair. , 2003, Drug discovery today.
[28] A Tampieri,et al. A novel route in bone tissue engineering: magnetic biomimetic scaffolds. , 2010, Acta biomaterialia.
[29] Hyun D Kim,et al. Retention and activity of BMP-2 in hyaluronic acid-based scaffolds in vitro. , 2002, Journal of biomedical materials research.
[30] Jennifer L. Moreau,et al. Mesenchymal stem cell proliferation and differentiation on an injectable calcium phosphate-chitosan composite scaffold. , 2009, Biomaterials.
[31] Johnny Huard,et al. VEGF Improves, Whereas sFlt1 Inhibits, BMP2‐Induced Bone Formation and Bone Healing Through Modulation of Angiogenesis , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[32] M. Morra,et al. Surface engineering of titanium by collagen immobilization. Surface characterization and in vitro and in vivo studies. , 2003, Biomaterials.
[33] G. C. Chan,et al. Mesenchymal stem cell-encapsulated collagen microspheres for bone tissue engineering. , 2010, Tissue engineering. Part C, Methods.
[34] Antonios G Mikos,et al. Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model. , 2008, Bone.
[35] Paula T Hammond,et al. Tunable dual growth factor delivery from polyelectrolyte multilayer films. , 2011, Biomaterials.
[36] Cato T. Laurencin,et al. Bone-Graft Substitutes: Facts, Fictions, and Applications , 2001, The Journal of bone and joint surgery. American volume.
[37] E. Hunziker,et al. BMP-2 liberated from biomimetic implant coatings induces and sustains direct ossification in an ectopic rat model. , 2005, Bone.
[38] Sha Huang,et al. Release of bioactive BMP from dextran-derived microspheres: a novel delivery concept. , 2006, International journal of pharmaceutics.
[39] Robert Gurny,et al. Novel thermosensitive chitosan hydrogels: in vivo evaluation. , 2009, Journal of biomedical materials research. Part A.
[40] V. Rosen,et al. Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[41] J. Wozney,et al. Characterization of rhBMP-2 pharmacokinetics implanted with biomaterial carriers in the rat ectopic model. , 1999, Journal of biomedical materials research.
[42] F K Kasper,et al. Effects of TGF-beta3 and preculture period of osteogenic cells on the chondrogenic differentiation of rabbit marrow mesenchymal stem cells encapsulated in a bilayered hydrogel composite. , 2010, Acta biomaterialia.
[43] Yasuhiko Tabata,et al. Regenerative inductive therapy based on DDS technology of protein and gene , 2006, Journal of drug targeting.
[44] S. Bidic,et al. rhBMP-2 delivered in a calcium phosphate cement accelerates bridging of critical-sized defects in rabbit radii. , 2006, The Journal of bone and joint surgery. American volume.
[45] Casey K Chan,et al. Cell therapy for bone regeneration--bench to bedside. , 2009, Journal of biomedical materials research. Part B, Applied biomaterials.
[46] U. Ripamonti. Soluble osteogenic molecular signals and the induction of bone formation. , 2006, Biomaterials.
[47] Seok-Jung Kim,et al. A multi-center, randomized, clinical study to compare the effect and safety of autologous cultured osteoblast(Ossron™) injection to treat fractures , 2009, BMC Musculoskeletal Disorders.
[48] A. Goepferich,et al. Enhanced bone morphogenetic protein-2 performance on hydroxyapatite ceramic surfaces. , 2009, Journal of biomedical materials research. Part A.
[49] D. Mooney,et al. Growth factor delivery-based tissue engineering: general approaches and a review of recent developments , 2011, Journal of The Royal Society Interface.
[50] Ximeng Sun,et al. Inorganic–organic hybrid alginate beads with LCST near human body temperature for sustained dual‐sensitive drug delivery , 2008 .
[51] J. Kanczler,et al. Osteogenesis and angiogenesis: the potential for engineering bone. , 2008, European cells & materials.
[52] Johnny Huard,et al. Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4. , 2002, The Journal of clinical investigation.
[53] J. Tao,et al. Induced Endothelial Cells Enhance Osteogenesis and Vascularization of Mesenchymal Stem Cells , 2009, Cells Tissues Organs.
[54] K. Nguyen,et al. A review of materials, fabrication methods, and strategies used to enhance bone regeneration in engineered bone tissues. , 2008, Journal of biomedical materials research. Part B, Applied biomaterials.
[55] J. Hollinger,et al. A Bone Regeneration Study: Transforming Growth Factor‐β1 and Its Delivery , 1996 .
[56] Rui L Reis,et al. Crosstalk between osteoblasts and endothelial cells co-cultured on a polycaprolactone-starch scaffold and the in vitro development of vascularization. , 2009, Biomaterials.
[57] Daocheng Wu,et al. Preparation and property of a novel bone graft composite consisting of rhBMP-2 loaded PLGA microspheres and calcium phosphate cement , 2008, Journal of materials science. Materials in medicine.
[58] Ann-Christine Albertsson,et al. A strategy for the covalent functionalization of resorbable polymers with heparin and osteoinductive growth factor. , 2008, Biomacromolecules.
[59] D. Puleo,et al. A technique to immobilize bioactive proteins, including bone morphogenetic protein-4 (BMP-4), on titanium alloy. , 2002, Biomaterials.
[60] R. Bareille,et al. The effect of the co-immobilization of human osteoprogenitors and endothelial cells within alginate microspheres on mineralization in a bone defect. , 2009, Biomaterials.
[61] J. Jansen,et al. Analysis of the osteoinductive capacity and angiogenicity of an in vitro generated extracellular matrix. , 2009, Journal of biomedical materials research. Part A.
[62] Federica Chiellini,et al. Polymeric Materials for Bone and Cartilage Repair , 2010 .
[63] A. Mikos,et al. In vitro generation of an osteochondral construct using injectable hydrogel composites encapsulating rabbit marrow mesenchymal stem cells. , 2009, Biomaterials.
[64] Carl G Simon,et al. Injectable and strong nano-apatite scaffolds for cell/growth factor delivery and bone regeneration. , 2008, Dental materials : official publication of the Academy of Dental Materials.
[65] K. Matyjaszewski,et al. Influence of cross-linker chemistry on release kinetics of PEG-co-PGA hydrogels. , 2009, Journal of biomedical materials research. Part A.
[66] H. Burt,et al. The differential in vitro and in vivo responses of bone marrow stromal cells on novel porous gelatin–alginate scaffolds , 2009, Journal of tissue engineering and regenerative medicine.
[67] W. Lu,et al. Gene therapy for new bone formation using adeno-associated viral bone morphogenetic protein-2 vectors , 2003, Gene Therapy.
[68] Y. Carvalho,et al. Effect of calcitonin on bone regeneration in male rats: a histomorphometric analysis. , 2007, International journal of oral and maxillofacial surgery.
[69] A. Lode,et al. Influence of modified extracellular matrices on TI6AL4V implants on binding and release of VEGF. , 2006, Journal of biomedical materials research. Part A.
[70] Antonios G Mikos,et al. Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model. , 2009, Tissue engineering. Part A.
[71] H. Schliephake. Application of bone growth factors—the potential of different carrier systems , 2009, Oral and Maxillofacial Surgery.
[72] Jin Chang,et al. PLGA/polymeric liposome for targeted drug and gene co-delivery. , 2010, Biomaterials.
[73] Jaesoon Choi,et al. In vivo evaluation of MMP sensitive high-molecular weight HA-based hydrogels for bone tissue engineering. , 2010, Journal of biomedical materials research. Part A.
[74] C James Kirkpatrick,et al. Microvessel-like structures from outgrowth endothelial cells from human peripheral blood in 2-dimensional and 3-dimensional co-cultures with osteoblastic lineage cells. , 2007, Tissue engineering.
[75] Ueon Sang Shin,et al. Direct deposited porous scaffolds of calcium phosphate cement with alginate for drug delivery and bone tissue engineering. , 2011, Acta biomaterialia.
[76] Yasuhiko Tabata,et al. In Vitro and In Vivo Release of Basic Fibroblast Growth Factor Using a Silk Fibroin Scaffold as Delivery Carrier , 2010, Journal of biomaterials science. Polymer edition.
[77] K. So,et al. Fabrication of nano-fibrous collagen microspheres for protein delivery and effects of photochemical crosslinking on release kinetics. , 2008, Journal of controlled release : official journal of the Controlled Release Society.
[78] E. Korgun,et al. Human fetal placental endothelial cells have a mature arterial and a juvenile venous phenotype with adipogenic and osteogenic differentiation potential. , 2008, Differentiation; research in biological diversity.
[79] Dietmar W Hutmacher,et al. Co-culture of bone marrow fibroblasts and endothelial cells on modified polycaprolactone substrates for enhanced potentials in bone tissue engineering. , 2006, Tissue engineering.
[80] Shigeru Kobayashi,et al. Bone formation on apatite-coated titanium with incorporated BMP-2/heparin in vivo. , 2009, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.
[81] M. Marcacci,et al. A conceptually new type of bio-hybrid scaffold for bone regeneration , 2011, Nanotechnology.
[82] K. Healy,et al. Biomimetic artificial ECMs stimulate bone regeneration. , 2006, Journal of biomedical materials research. Part A.
[83] D. Scharnweber,et al. Evaluation of osseointegration of dental implants coated with collagen, chondroitin sulphate and BMP-4: an animal study. , 2008, International journal of oral and maxillofacial surgery.
[84] Bin Wu,et al. Preparation and ectopic osteogenesis in vivo of scaffold based on mineralized recombinant human-like collagen loaded with synthetic BMP-2-derived peptide , 2008, Biomedical materials.
[85] Maik Stiehler,et al. Bioreactor systems for bone tissue engineering. , 2011, Tissue engineering. Part B, Reviews.
[86] T. Miclau,et al. Autologous iliac crest bone graft: should it still be the gold standard for treating nonunions? , 2007, Injury.
[87] A. Metters,et al. Hydrogels in controlled release formulations: network design and mathematical modeling. , 2006, Advanced drug delivery reviews.
[88] A. Mikos,et al. Osteogenic differentiation of mesenchymal stem cells on pregenerated extracellular matrix scaffolds in the absence of osteogenic cell culture supplements. , 2010, Tissue engineering. Part A.
[89] Allan S Hoffman,et al. Injectable pH- and temperature-responsive poly(N-isopropylacrylamide-co-propylacrylic acid) copolymers for delivery of angiogenic growth factors. , 2010, Biomacromolecules.
[90] David A. Wang,et al. Prospective evaluation of chronic pain associated with posterior autologous iliac crest bone graft harvest and its effect on postoperative outcome , 2009, Health and quality of life outcomes.
[91] M. Wendel,et al. Bone matrix formation in osteogenic cultures derived from human embryonic stem cells in vitro. , 2007, Stem cells and development.
[92] C. Ge,et al. Use of a stringent dimerizer-regulated gene expression system for controlled BMP2 delivery. , 2006, Molecular therapy : the journal of the American Society of Gene Therapy.
[93] Antonios G Mikos,et al. Modulation of the inflammatory response for enhanced bone tissue regeneration. , 2008, Tissue engineering. Part B, Reviews.
[94] K. Lau,et al. Retroviral‐based gene therapy with cyclooxygenase‐2 promotes the union of bony callus tissues and accelerates fracture healing in the rat , 2008, The journal of gene medicine.
[95] David J Mooney,et al. Coating of VEGF-releasing scaffolds with bioactive glass for angiogenesis and bone regeneration. , 2006, Biomaterials.
[96] K. Ishihara,et al. Controlled drug release from multilayered phospholipid polymer hydrogel on titanium alloy surface. , 2009, Biomaterials.
[97] A. Khademhosseini,et al. Creation of bony microenvironment with CaP and cell-derived ECM to enhance human bone-marrow MSC behavior and delivery of BMP-2. , 2011, Biomaterials.
[98] Yasuhiko Tabata,et al. Enhanced bone regeneration at a segmental bone defect by controlled release of bone morphogenetic protein-2 from a biodegradable hydrogel. , 2006, Tissue engineering.
[99] A. Mikos,et al. Modulation of osteogenic properties of biodegradable polymer/extracellular matrix scaffolds generated with a flow perfusion bioreactor. , 2010, Acta biomaterialia.
[100] A. Mikos,et al. Modulation of differentiation and mineralization of marrow stromal cells cultured on biomimetic hydrogels modified with Arg-Gly-Asp containing peptides. , 2004, Journal of biomedical materials research. Part A.
[101] Austin G Smith,et al. Osteogenic and chondrogenic differentiation of embryonic stem cells in response to specific growth factors. , 2005, Bone.
[102] C. Kirker-Head,et al. Potential applications and delivery strategies for bone morphogenetic proteins. , 2000, Advanced drug delivery reviews.
[103] A. Matsumura,et al. Enhanced bone formation using hydroxyapatite ceramic coated with fibroblast growth factor-2. , 2010, Acta biomaterialia.
[104] Johnna S Temenoff,et al. Engineering orthopedic tissue interfaces. , 2009, Tissue engineering. Part B, Reviews.
[105] D W Hutmacher,et al. The stimulation of healing within a rat calvarial defect by mPCL-TCP/collagen scaffolds loaded with rhBMP-2. , 2009, Biomaterials.
[106] C. Tsakiroglou,et al. Liposomal drugs dispersed in hydrogels. Effect of liposome, drug and gel properties on drug release kinetics. , 2007, Colloids and surfaces. B, Biointerfaces.
[107] Heungsoo Shin,et al. Matrices and scaffolds for delivery of bioactive molecules in bone and cartilage tissue engineering. , 2007, Advanced drug delivery reviews.
[108] K. Anseth,et al. Repair of a calvarial defect with biofactor and stem cell-embedded polyethylene glycol scaffold. , 2010, Archives of facial plastic surgery.
[109] R L Reis,et al. Journal of Tissue Engineering and Regenerative Medicine Silk Fibroin Microparticles as Carriers for Delivery of Human Recombinant Bmps. Physical Characterization and Drug Release , 2022 .
[110] Matthias P Lutolf,et al. Biomimetic PEG hydrogels crosslinked with minimal plasmin-sensitive tri-amino acid peptides. , 2009, Journal of biomedical materials research. Part A.
[111] Bernard A Roos,et al. Low oxygen tension inhibits osteogenic differentiation and enhances stemness of human MIAMI cells. , 2006, Bone.
[112] William V Giannobile,et al. The enhancement of osteogenesis by nano-fibrous scaffolds incorporating rhBMP-7 nanospheres. , 2007, Biomaterials.
[113] K. Mäder,et al. The influence of covalently linked and free polyethylene glycol on the structural and release properties of rhBMP-2 loaded microspheres. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[114] J. Wiltfang,et al. Survival of transplanted rat bone marrow-derived osteogenic stem cells in vivo. , 2011, Tissue engineering. Part A.
[115] Zhifeng Xiao,et al. Improved cellularization and angiogenesis using collagen scaffolds chemically conjugated with vascular endothelial growth factor. , 2011, Acta biomaterialia.
[116] J. Goh,et al. Growth factor delivery through electrospun nanofibers in scaffolds for tissue engineering applications. , 2009, Journal of biomedical materials research. Part A.
[117] Pol Maria Rommens,et al. The effect of human osteoblasts on proliferation and neo-vessel formation of human umbilical vein endothelial cells in a long-term 3D co-culture on polyurethane scaffolds. , 2008, Biomaterials.
[118] Y. Tabata,et al. Controlled release of platelet growth factors enhances bone regeneration at rabbit calvaria. , 2007, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.
[119] Antonios G Mikos,et al. Gelatin as a delivery vehicle for the controlled release of bioactive molecules. , 2005, Journal of controlled release : official journal of the Controlled Release Society.
[120] E. Galun,et al. Gene therapy platform for bone regeneration using an exogenously regulated, AAV-2-based gene expression system. , 2004, Molecular therapy : the journal of the American Society of Gene Therapy.
[121] David J Mooney,et al. Cell delivery mechanisms for tissue repair. , 2008, Cell stem cell.
[122] Gorka Orive,et al. Delivering growth factors for therapeutics. , 2008, Trends in pharmacological sciences.
[123] U. Ripamonti,et al. Tissue engineering: TGF-β superfamily members and delivery systems in bone regeneration , 2002, Expert Reviews in Molecular Medicine.
[124] Eunhee Cho,et al. A novel synthetic route for the preparation of hydrolytically degradable synthetic hydrogels. , 2009, Journal of biomedical materials research. Part A.
[125] J. Fisher,et al. Bone tissue engineering bioreactors: dynamic culture and the influence of shear stress. , 2011, Bone.
[126] Chengtie Wu,et al. Porous bioactive diopside (CaMgSi(2)O(6)) ceramic microspheres for drug delivery. , 2010, Acta biomaterialia.
[127] N. Ferrara,et al. Angiogenesis and bone growth. , 2000, Trends in cardiovascular medicine.
[128] Antonios G Mikos,et al. Mineralization of hydrogels for bone regeneration. , 2010, Tissue engineering. Part B, Reviews.
[129] David L Kaplan,et al. Osteogenesis by human mesenchymal stem cells cultured on silk biomaterials: comparison of adenovirus mediated gene transfer and protein delivery of BMP-2. , 2006, Biomaterials.
[130] Byung-Soo Kim,et al. Heparin-conjugated fibrin as an injectable system for sustained delivery of bone morphogenetic protein-2. , 2010, Tissue engineering. Part A.
[131] H. Lee,et al. In vivo osteogenic differentiation of rat bone marrow stromal cells in thermosensitive MPEG-PCL diblock copolymer gels. , 2006, Tissue engineering.
[132] D. Schaffer,et al. Engineering biomaterial systems to enhance viral vector gene delivery. , 2011, Molecular therapy : the journal of the American Society of Gene Therapy.
[133] J. Jansen,et al. In vitro degradation rate of apatitic calcium phosphate cement with incorporated PLGA microspheres. , 2011, Acta biomaterialia.
[134] J. Jansen,et al. The effect of a low dose of transforming growth factor beta1 (TGF-beta1) on the early bone-healing around oral implants inserted in trabecular bone. , 2009, Biomaterials.
[135] W. Friess,et al. Collagen sponges for bone regeneration with rhBMP-2. , 2003, Advanced drug delivery reviews.
[136] Ana Jaklenec,et al. Sequential release of bioactive IGF-I and TGF-beta 1 from PLGA microsphere-based scaffolds. , 2008, Biomaterials.
[137] Charles A Gersbach,et al. Virus-based gene therapy strategies for bone regeneration. , 2007, Biomaterials.
[138] J. Jansen,et al. Bone inductive properties of rhBMP-2 loaded porous calcium phosphate cement implants inserted at an ectopic site in rabbits. , 2005, Biomaterials.
[139] C. Tonda-Turo,et al. Incorporation of PLGA nanoparticles into porous chitosan-gelatin scaffolds: influence on the physical properties and cell behavior. , 2011, Journal of the mechanical behavior of biomedical materials.
[140] S. Ahmed,et al. Biology and clinical applications , 2004 .
[141] M. Schulz-Siegmund,et al. VEGF-controlled release within a bone defect from alginate/chitosan/PLA-H scaffolds. , 2009, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[142] A. Metters,et al. Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: Engineering cell-invasion characteristics , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[143] J. Fischer,et al. Cell therapy in bone healing disorders , 2010, Orthopedic reviews.
[144] R. Reis,et al. Drug delivery therapies II. Strategies for delivering bone regenerating factors , 2002 .
[145] Michael J Yaszemski,et al. Three-dimensional porous biodegradable polymeric scaffolds fabricated with biodegradable hydrogel porogens. , 2009, Tissue engineering. Part C, Methods.
[146] Yasuhiko Tabata,et al. Controlled release of bone morphogenetic protein-2 enhances recruitment of osteogenic progenitor cells for de novo generation of bone tissue. , 2010, Tissue engineering. Part A.
[147] Vasif Hasirci,et al. Sequential growth factor delivery from complexed microspheres for bone tissue engineering. , 2008, Biomaterials.
[148] J. Conway. Autograft and nonunions: morbidity with intramedullary bone graft versus iliac crest bone graft. , 2010, The Orthopedic clinics of North America.
[149] D W Hutmacher,et al. Novel PCL-based honeycomb scaffolds as drug delivery systems for rhBMP-2. , 2005, Biomaterials.
[150] Peter C. Johnson,et al. Challenges in tissue engineering and regenerative medicine product commercialization: building an industry. , 2011, Tissue engineering. Part A.
[151] Min Zhang,et al. Toward delivery of multiple growth factors in tissue engineering. , 2010, Biomaterials.
[152] Chaoliang He,et al. In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery. , 2008, Journal of controlled release : official journal of the Controlled Release Society.
[153] Emil H Schemitsch,et al. Growth factors and bone regeneration: how much bone can we expect? , 2011, Injury.
[154] K. Siebenrock,et al. Long-term cell-mediated protein release from calcium phosphate ceramics. , 2009, Journal of biomedical materials research. Part A.
[155] Eyal Zussman,et al. Slow-release human recombinant bone morphogenetic protein-2 embedded within electrospun scaffolds for regeneration of bone defect: in vitro and in vivo evaluation. , 2011, Tissue engineering. Part A.
[156] T. Hefferan,et al. Enhanced bone morphogenetic protein-2-induced ectopic and orthotopic bone formation by intermittent parathyroid hormone (1-34) administration. , 2010, Tissue engineering. Part A.
[157] J. Heckman,et al. Bone morphogenetic protein but not transforming growth factor-beta enhances bone formation in canine diaphyseal nonunions implanted with a biodegradable composite polymer. , 1999, The Journal of bone and joint surgery. American volume.
[158] Antonios G Mikos,et al. Flow perfusion culture induces the osteoblastic differentiation of marrow stroma cell-scaffold constructs in the absence of dexamethasone. , 2005, Journal of biomedical materials research. Part A.
[159] Michael J Yaszemski,et al. Retention of in vitro and in vivo BMP-2 bioactivities in sustained delivery vehicles for bone tissue engineering. , 2008, Biomaterials.
[160] F. Krummenauer,et al. Biological activity of recombinant human growth factors released from biocompatible bone implants. , 2008, Journal of biomedical materials research. Part A.
[161] Yourong Duan,et al. Novel thymopentin release systems prepared from bioresorbable PLA-PEG-PLA hydrogels. , 2010, International journal of pharmaceutics.
[162] Minhyung Lee,et al. Apatite-coated collagen scaffold for bone morphogenetic protein-2 delivery. , 2011, Tissue engineering. Part A.
[163] R. Oreffo,et al. Gene delivery in bone tissue engineering: progress and prospects using viral and nonviral strategies. , 2004, Tissue engineering.
[164] H. Yoo,et al. MMPs-responsive release of DNA from electrospun nanofibrous matrix for local gene therapy: in vitro and in vivo evaluation. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[165] N. Dahotre,et al. Calcium phosphate coatings for bio-implant applications: Materials, performance factors, and methodologies , 2009 .
[166] J. Jansen,et al. The kinetic and biological activity of different loaded rhBMP-2 calcium phosphate cement implants in rats. , 2008, Journal of biomedical materials research. Part A.
[167] J. Kinney,et al. Repair of rabbit segmental defects with the thrombin peptide, TP508 , 2004, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[168] D. Stewart,et al. Effect of cell‐based VEGF gene therapy on healing of a segmental bone defect , 2009, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[169] G. Pei,et al. Reconstruction of goat tibial defects using an injectable tricalcium phosphate/chitosan in combination with autologous platelet-rich plasma. , 2010, Biomaterials.
[170] D. Mooney,et al. Polymeric system for dual growth factor delivery , 2001, Nature Biotechnology.
[171] Antonios G Mikos,et al. Design of a flow perfusion bioreactor system for bone tissue-engineering applications. , 2003, Tissue engineering.
[172] S. Soker,et al. Osteogenic differentiation of human amniotic fluid-derived stem cells induced by bone morphogenetic protein-7 and enhanced by nanofibrous scaffolds. , 2010, Biomaterials.
[173] Christina Eckhardt,et al. Vascular Endothelial Growth Factor Gene‐Activated Matrix (VEGF165‐GAM) Enhances Osteogenesis and Angiogenesis in Large Segmental Bone Defects , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[174] Shu-Hua Yang,et al. Bone induction by biomimetic PLGA-(PEG-ASP)n copolymer loaded with a novel synthetic BMP-2-related peptide in vitro and in vivo. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[175] Richard O C Oreffo,et al. The effect of the delivery of vascular endothelial growth factor and bone morphogenic protein-2 to osteoprogenitor cell populations on bone formation. , 2010, Biomaterials.
[176] Benjamin M. Wu,et al. Biomimetic apatite-coated alginate/chitosan microparticles as osteogenic protein carriers. , 2009, Biomaterials.
[177] E. Kang,et al. Injectable in situ-forming pH/thermo-sensitive hydrogel for bone tissue engineering. , 2009, Tissue engineering. Part A.
[178] X. Marchandise,et al. Evaluation of human recombinant bone morphogenetic protein-2-loaded tricalcium phosphate implants in rabbits' bone defects. , 1999, Bone.
[179] M. Urist. Bone: Formation by Autoinduction , 1965, Science.
[180] K. Na,et al. Osteogenic differentiation of rabbit mesenchymal stem cells in thermo-reversible hydrogel constructs containing hydroxyapatite and bone morphogenic protein-2 (BMP-2). , 2007, Biomaterials.
[181] K E Healy,et al. A biodegradable polymer scaffold for delivery of osteotropic factors. , 2000, Biomaterials.
[182] A G Mikos,et al. Controlled release of rhBMP-2 loaded poly(dl-lactic-co-glycolic acid)/calcium phosphate cement composites in vivo. , 2005, Journal of controlled release : official journal of the Controlled Release Society.
[183] J. Fisher,et al. Nanoparticle technology in bone tissue engineering , 2007, Journal of drug targeting.
[184] Heung Jae Chun,et al. Fabrication of core-shell microcapsules using PLGA and alginate for dual growth factor delivery system. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[185] J. Jansen,et al. Effect of dual growth factor delivery on chondrogenic differentiation of rabbit marrow mesenchymal stem cells encapsulated in injectable hydrogel composites. , 2009, Journal of biomedical materials research. Part A.
[186] F. Singer,et al. Calcitonin stimulates bone formation when administered prior to initiation of osteogenesis. , 1981, The Journal of clinical investigation.
[187] Gabriela A Silva,et al. Natural-origin polymers as carriers and scaffolds for biomolecules and cell delivery in tissue engineering applications. , 2007, Advanced drug delivery reviews.
[188] Antonios G Mikos,et al. Harnessing and modulating inflammation in strategies for bone regeneration. , 2011, Tissue engineering. Part B, Reviews.
[189] T. Hefferan,et al. Potential of hydrogels based on poly(ethylene glycol) and sebacic acid as orthopedic tissue engineering scaffolds. , 2009, Tissue engineering. Part A.
[190] Takaaki Tanaka,et al. Repair of segmental bone defects in rabbit tibiae using a complex of beta-tricalcium phosphate, type I collagen, and fibroblast growth factor-2. , 2006, Biomaterials.
[191] Sung Min Kang,et al. Osteoconductive conjugation of bone morphogenetic protein-2 onto titanium/titanium oxide surfaces coated with non-biofouling poly(poly(ethylene glycol) methacrylate). , 2010, Colloids and surfaces. B, Biointerfaces.
[192] Fa-Ming Chen,et al. In vitro cellular responses to scaffolds containing two microencapulated growth factors. , 2009, Biomaterials.
[193] Yinghong Zhou,et al. In vitro and in vivo evaluation of adenovirus combined silk fibroin scaffolds for bone morphogenetic protein-7 gene delivery. , 2011, Tissue engineering. Part C, Methods.
[194] J. van den Dolder,et al. Bone formation in CaP-coated and noncoated titanium fiber mesh. , 2003, Journal of biomedical materials research. Part A.
[195] D. Kaplan,et al. Bone morphogenetic protein-2 binds as multilayers to a collagen delivery matrix: an equilibrium thermodynamic analysis. , 2006, Biomacromolecules.
[196] Ling Li,et al. Prospective study of iliac crest bone graft harvest site pain and morbidity. , 2009, The spine journal : official journal of the North American Spine Society.
[197] Antonios G Mikos,et al. Uncultured marrow mononuclear cells delivered within fibrin glue hydrogels to porous scaffolds enhance bone regeneration within critical-sized rat cranial defects. , 2010, Tissue engineering. Part A.
[198] Sang Hoon Lee,et al. Bone regeneration using hyaluronic acid-based hydrogel with bone morphogenic protein-2 and human mesenchymal stem cells. , 2007, Biomaterials.
[199] H. Sung,et al. Heparin-functionalized chitosan-alginate scaffolds for controlled release of growth factor. , 2009, International journal of pharmaceutics.
[200] J. Herzenberg,et al. Bone Graft Harvest Using a New Intramedullary System , 2008, Clinical orthopaedics and related research.
[201] Antonios G Mikos,et al. In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[202] Jennifer Patterson,et al. Hyaluronic acid hydrogels with controlled degradation properties for oriented bone regeneration. , 2010, Biomaterials.
[203] S. Bhang,et al. Long-term delivery enhances in vivo osteogenic efficacy of bone morphogenetic protein-2 compared to short-term delivery. , 2008, Biochemical and biophysical research communications.
[204] P H Krebsbach,et al. Localized viral vector delivery to enhance in situ regenerative gene therapy , 2007, Gene Therapy.
[205] Pieter Buma,et al. Anisotropic Porous Biodegradable Scaffolds for Musculoskeletal Tissue Engineering , 2009, Materials.
[206] J. Miyazaki,et al. Simple strategy for bone regeneration with a BMP-2/7 gene expression cassette vector. , 2009, Biochemical and biophysical research communications.
[207] S. Goldstein,et al. Stimulation of new bone formation by direct transfer of osteogenic plasmid genes. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[208] Jian Dong,et al. The repair of large segmental bone defects in the rabbit with vascularized tissue engineered bone. , 2010, Biomaterials.
[209] Thomas J Webster,et al. Ceramic/polymer nanocomposites with tunable drug delivery capability at specific disease sites. , 2009, Journal of biomedical materials research. Part A.
[210] R. Reis,et al. Silk fibroin microparticles as carriers for delivery of human recombinant bone morphogenetic protein-2: in vitro and in vivo bioactivity. , 2010, Tissue engineering. Part C, Methods.
[211] Antonios G Mikos,et al. In vivo bone and soft tissue response to injectable, biodegradable oligo(poly(ethylene glycol) fumarate) hydrogels. , 2003, Biomaterials.
[212] Maria Luisa Brandi,et al. Vascular Biology and the Skeleton , 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[213] Henning Schliephake,et al. Mandibular bone repair by implantation of rhBMP-2 in a slow release carrier of polylactic acid--an experimental study in rats. , 2008, Biomaterials.
[214] Jeffrey C. Wang,et al. Comparison of Lentiviral and Adenoviral Gene Therapy for Spinal Fusion in Rats , 2008, Spine.
[215] Aldo R Boccaccini,et al. The pro-angiogenic properties of multi-functional bioactive glass composite scaffolds. , 2011, Biomaterials.
[216] Hani Awad,et al. Direct gene therapy for bone regeneration: gene delivery, animal models, and outcome measures. , 2009, Tissue engineering. Part B, Reviews.
[217] H. Seeherman,et al. Delivery of bone morphogenetic proteins for orthopedic tissue regeneration. , 2005, Cytokine & growth factor reviews.
[218] Kristi S. Anseth,et al. PEG Hydrogels for the Controlled Release of Biomolecules in Regenerative Medicine , 2009, Pharmaceutical Research.
[219] Robert E Guldberg,et al. Sustained release of BMP-2 in a lipid-based microtube vehicle. , 2009, Acta biomaterialia.
[220] J. van den Dolder,et al. Bone response and mechanical strength of rabbit femoral defects filled with injectable CaP cements containing TGF-beta 1 loaded gelatin microparticles. , 2008, Biomaterials.
[221] T A Einhorn,et al. Growth Factor Regulation of Fracture Repair , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[222] A. Caplan. New era of cell-based orthopedic therapies. , 2009, Tissue engineering. Part B, Reviews.
[223] David J Mooney,et al. VEGF Scaffolds Enhance Angiogenesis and Bone Regeneration in Irradiated Osseous Defects , 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[224] Eleftherios Tsiridis,et al. Current concepts of molecular aspects of bone healing. , 2005, Injury.
[225] J. Reginster,et al. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. , 2001, The New England journal of medicine.
[226] A. Turner,et al. In vivo BMP-7 (OP-1) enhancement of osteoporotic vertebral bodies in an ovine model. , 2006, The spine journal : official journal of the North American Spine Society.
[227] Hasan Uludağ,et al. Nanoparticulate Systems for Growth Factor Delivery , 2009, Pharmaceutical Research.
[228] Christian Koch,et al. A strategy to establish a gene-activated matrix on titanium using gene vectors protected in a polylactide coating. , 2011, Biomaterials.
[229] Y. Tabata,et al. Bone regeneration using titanium nonwoven fabrics combined with fgf-2 release from gelatin hydrogel microspheres in rabbit skull defects. , 2008, Tissue engineering. Part A.
[230] Bochu Wang,et al. Factors affecting protein release from microcapsule prepared by liposome in alginate. , 2005, Colloids and surfaces. B, Biointerfaces.
[231] G. Pelled,et al. Ultrasound-based nonviral gene delivery induces bone formation in vivo , 2008, Gene Therapy.
[232] David Dean,et al. Bone formation in transforming growth factor beta-1-coated porous poly(propylene fumarate) scaffolds. , 2002, Journal of biomedical materials research.
[233] M. Leigheb,et al. Effect of different growth factors on human osteoblasts activities: a possible application in bone regeneration for tissue engineering. , 2007, Biomolecular engineering.
[234] J. Huard,et al. Development of a self-inactivating tet-on retroviral vector expressing bone morphogenetic protein 4 to achieve regulated bone formation. , 2004, Molecular therapy : the journal of the American Society of Gene Therapy.
[235] J. Jansen,et al. Mineralization, biodegradation, and drug release behavior of gelatin/apatite composite microspheres for bone regeneration. , 2010, Biomacromolecules.
[236] Günter Finkenzeller,et al. Bone formation and neovascularization mediated by mesenchymal stem cells and endothelial cells in critical-sized calvarial defects. , 2011, Tissue engineering. Part A.
[237] Raul Machado,et al. Thermoresponsive self-assembled elastin-based nanoparticles for delivery of BMPs. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[238] Helen H. Lu,et al. Controlled delivery of platelet-rich plasma-derived growth factors for bone formation. , 2008, Journal of biomedical materials research. Part A.
[239] Michael J Yaszemski,et al. Non-invasive monitoring of BMP-2 retention and bone formation in composites for bone tissue engineering using SPECT/CT and scintillation probes. , 2009, Journal of controlled release : official journal of the Controlled Release Society.
[240] M. Tabrizian,et al. A hybrid rhOP-1 delivery system enhances new bone regeneration and consolidation in a rabbit model of distraction osteogenesis , 2010, Growth factors.
[241] M. Liebergall,et al. Nucleofection-based ex vivo nonviral gene delivery to human stem cells as a platform for tissue regeneration. , 2006, Tissue engineering.
[242] Cato T Laurencin,et al. Induction of angiogenesis in tissue-engineered scaffolds designed for bone repair: A combined gene therapy–cell transplantation approach , 2008, Proceedings of the National Academy of Sciences.
[243] C. Chung,et al. Enhanced bone formation by transforming growth factor-beta1-releasing collagen/chitosan microgranules. , 2006, Journal of biomedical materials research. Part A.
[244] T. Nishihara,et al. Heparin inhibits BMP‐2 osteogenic bioactivity by binding to both BMP‐2 and BMP receptor , 2008, Journal of cellular physiology.
[245] E. Jabbari,et al. Effect of encapsulation or grafting on release kinetics of recombinant human bone morphogenetic protein‐2 from self‐assembled poly(lactide‐co‐glycolide ethylene oxide fumarate) nanoparticles , 2010, Microscopy research and technique.
[246] T. Lenarz,et al. Amino-modified silica surfaces efficiently immobilize bone morphogenetic protein 2 (BMP2) for medical purposes. , 2011, Acta biomaterialia.
[247] T. Webster,et al. Molecular plasma deposited peptides on anodized nanotubular titanium: an osteoblast density study. , 2011, Journal of biomedical materials research. Part A.
[248] J. Mano. Stimuli‐Responsive Polymeric Systems for Biomedical Applications , 2008 .
[249] K. Shakesheff,et al. The effect of mesenchymal populations and vascular endothelial growth factor delivered from biodegradable polymer scaffolds on bone formation. , 2008, Biomaterials.
[250] David J Mooney,et al. Quantitative assessment of scaffold and growth factor‐mediated repair of critically sized bone defects , 2007, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[251] H. Seeherman,et al. Protein-based tissue engineering in bone and cartilage repair. , 2004, Current Opinion in Biotechnology.
[252] M. Farach-Carson,et al. Perlecan domain I promotes fibroblast growth factor 2 delivery in collagen I fibril scaffolds. , 2005, Tissue engineering.
[253] Y. Tabata,et al. Use of collagen sponge incorporating transforming growth factor-beta1 to promote bone repair in skull defects in rabbits. , 2002, Biomaterials.
[254] J Amédée,et al. Cell-to-cell communication between osteogenic and endothelial lineages: implications for tissue engineering. , 2009, Trends in biotechnology.
[255] D. Mooney,et al. Combined Angiogenic and Osteogenic Factor Delivery Enhances Bone Marrow Stromal Cell‐Driven Bone Regeneration , 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[256] David J Mooney,et al. An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects. , 2011, Biomaterials.
[257] J. Hubbell,et al. Bone healing induced by local delivery of an engineered parathyroid hormone prodrug. , 2009, Biomaterials.
[258] A. Ammann,et al. An intraosseous device for studies of bone-healing. The effect of transforming growth-factor beta. , 1992, The Journal of bone and joint surgery. American volume.
[259] L. Schmidt‐Mende,et al. ZnO - nanostructures, defects, and devices , 2007 .
[260] K. Shiba,et al. Directional BMP-2 for functionalization of titanium surfaces. , 2009, Biomaterials.
[261] Junfeng Zhang,et al. Simultaneous regeneration of articular cartilage and subchondral bone in vivo using MSCs induced by a spatially controlled gene delivery system in bilayered integrated scaffolds. , 2011, Biomaterials.
[262] Xuebin B. Yang,et al. Human osteoprogenitor bone formation using encapsulated bone morphogenetic protein 2 in porous polymer scaffolds. , 2004, Tissue engineering.
[263] J. Jansen,et al. Ceramic composites as matrices and scaffolds for drug delivery in tissue engineering. , 2007, Advanced drug delivery reviews.
[264] Antonios G Mikos,et al. Biodegradable gelatin microparticles as delivery systems for the controlled release of bone morphogenetic protein-2. , 2008, Acta biomaterialia.
[265] E. Schwarz,et al. Review: gene- and stem cell-based therapeutics for bone regeneration and repair. , 2007, Tissue engineering.
[266] Benjamin M Wu,et al. High doses of bone morphogenetic protein 2 induce structurally abnormal bone and inflammation in vivo. , 2011, Tissue engineering. Part A.
[267] Qixin Zheng,et al. Porous nano-HA/collagen/PLLA scaffold containing chitosan microspheres for controlled delivery of synthetic peptide derived from BMP-2. , 2009, Journal of controlled release : official journal of the Controlled Release Society.
[268] Aaron Schindeler,et al. Bone remodeling during fracture repair: The cellular picture. , 2008, Seminars in cell & developmental biology.
[269] Bai Yang,et al. In vitro and in vivo effects of rat kidney vascular endothelial cells on osteogenesis of rat bone marrow mesenchymal stem cells growing on polylactide-glycoli acid (PLGA) scaffolds , 2007, Biomedical engineering online.
[270] J. Jansen,et al. Degradable hydrogel scaffolds for in vivo delivery of single and dual growth factors in cartilage repair. , 2007, Osteoarthritis and cartilage.
[271] P. Giannoudis,et al. Molecular aspects of fracture healing: which are the important molecules? , 2007, Injury.
[272] J A Planell,et al. Calcium phosphate cements as bone drug delivery systems: a review. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[273] M. Wendel,et al. Cell-derived matrix enhances osteogenic properties of hydroxyapatite. , 2011, Tissue engineering. Part A.
[274] V. Hasırcı,et al. Sequential BMP-2/BMP-7 delivery from polyester nanocapsules. , 2009, Journal of biomedical materials research. Part A.
[275] A. Mikos,et al. Attachment, proliferation, and migration of marrow stromal osteoblasts cultured on biomimetic hydrogels modified with an osteopontin-derived peptide. , 2004, Biomaterials.
[276] Jason A Burdick,et al. Delivery of osteoinductive growth factors from degradable PEG hydrogels influences osteoblast differentiation and mineralization. , 2002, Journal of controlled release : official journal of the Controlled Release Society.
[277] Eben Alsberg,et al. Affinity-based growth factor delivery using biodegradable, photocrosslinked heparin-alginate hydrogels. , 2011, Journal of controlled release : official journal of the Controlled Release Society.
[278] Timo Jämsä,et al. Adenoviral VEGF‐A gene transfer induces angiogenesis and promotes bone formation in healing osseous tissues , 2003, The journal of gene medicine.
[279] Jay R Lieberman,et al. The role of growth factors in the repair of bone. Biology and clinical applications. , 2002, The Journal of bone and joint surgery. American volume.
[280] M. Kassem,et al. Selective isolation and differentiation of a stromal population of human embryonic stem cells with osteogenic potential. , 2010, Bone.
[281] Jong-Ho Lee,et al. Enhanced bone regeneration with BMP-2 loaded functional nanoparticle-hydrogel complex. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[282] B. Melsen,et al. Human recombinant transforming growth factor-beta 1 in healing of calvarial bone defects. , 1996, The Journal of craniofacial surgery.
[283] S. Bronson,et al. Derivation of murine induced pluripotent stem cells (iPS) and assessment of their differentiation toward osteogenic lineage , 2009, Journal of cellular biochemistry.
[284] A. Dierich,et al. Active multilayered capsules for in vivo bone formation , 2010, Proceedings of the National Academy of Sciences.
[285] C. Plank,et al. Future of local bone regeneration - Protein versus gene therapy. , 2011, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.
[286] Paul H Wooley,et al. Promotion of osteogenesis in tissue‐engineered bone by pre‐seeding endothelial progenitor cells‐derived endothelial cells , 2008, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[287] K. Lau,et al. LMP-1 Retroviral Gene Therapy Influences Osteoblast Differentiation and Fracture Repair: A Preliminary Study , 2008, Calcified Tissue International.
[288] Marc Long,et al. Bone Graft Substitutes , 2003 .
[289] Teruyuki Nagamune,et al. Bone regeneration using collagen type I vitrigel with bone morphogenetic protein-2. , 2009, Journal of bioscience and bioengineering.
[290] Jeffrey C. Wang,et al. Comparison of Human Mesenchymal Stem Cells Derived From Adipose Tissue and Bone Marrow for Ex Vivo Gene Therapy in Rat Spinal Fusion Model , 2008, Spine.
[291] D. Scharnweber,et al. Immobilization of oligonucleotides on titanium based materials by partial incorporation in anodic oxide layers. , 2009, Biomaterials.