Azidomorphine: Subjective effects and suppression of morphine abstinence

In man, azidomorphine, a new morphine congener, constricted pupils, produced morphine‐like subjective effects and euphoria, and suppressed the morphine abstinence syndrome. Azidomorphine was 10 to 50 times as potent as morphine. It is concluded that in man azidomorphine is a typical morphine‐like drug.

[1]  S. Koerner,et al.  Clinical pharmacological studies with 6-azidomorphine. , 1976, Drug and alcohol dependence.

[2]  S. Fûrst,et al.  The pharmacology of azidomorphine and azidocodeine , 1973, The Journal of pharmacy and pharmacology.

[3]  R. Hoeldtke,et al.  Studies of the dependence‐producing properties of GPA‐1657, profadol, and propiram in man , 1971, Clinical pharmacology and therapeutics.

[4]  W. Martin,et al.  A comparison of fentanyl, droperidol, and morphine. , 1966, Clinical pharmacology and therapeutics.

[5]  W. Martin,et al.  Methods for evaluating addiction liability. (A) "Attitude" of opiate addicts toward opiate-like drugs. (B) a short-term "direct" addiction test. , 1961, The Journal of pharmacology and experimental therapeutics.

[6]  J. O. Irwin,et al.  Statistical Method in Biological Assay , 1953, Nature.