A green strategy to produce potential substitute resource for bear bile using engineered Saccharomyces cerevisiae

[1]  E. Carneiro,et al.  TUDCA receptors and their role on pancreatic beta cells. , 2021, Progress in biophysics and molecular biology.

[2]  E. Carneiro,et al.  The bile acid TUDCA and neurodegenerative disorders: An overview. , 2021, Life sciences.

[3]  Hai Hu,et al.  The effect of Tauroursodeoxycholic acid (TUDCA) and gut microbiota on murine gallbladder stone formation. , 2020, Annals of hepatology.

[4]  Lei Li,et al.  Taurochenodeoxycholic Acid Inhibited AP-1 Activation via Stimulating Glucocorticoid Receptor , 2019, Molecules.

[5]  Li Yang,et al.  Large-scale production of tauroursodeoxycholic acid products through fermentation optimization of engineered Escherichia coli cell factory , 2019, Microbial Cell Factories.

[6]  Bin Huang,et al.  Enhanced activity and substrate tolerance of 7α-hydroxysteroid dehydrogenase by directed evolution for 7-ketolithocholic acid production , 2019, Applied Microbiology and Biotechnology.

[7]  Huimin Zhao,et al.  Recent advances in metabolic engineering of Saccharomyces cerevisiae: New tools and their applications. , 2018, Metabolic engineering.

[8]  Zheng-Tao Wang,et al.  [Systematical analysis of multiple components in drainage bear bile powder from different sources]. , 2018, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[9]  I. Arends,et al.  Latest development in the synthesis of ursodeoxycholic acid (UDCA): a critical review , 2018, Beilstein journal of organic chemistry.

[10]  Bochu Wang,et al.  Discovery of tauroursodeoxycholic acid biotransformation enzymes from the gut microbiome of black bears using metagenomics , 2017, Scientific Reports.

[11]  Li Yang,et al.  Rapidly directional biotransformation of tauroursodeoxycholic acid through engineered Escherichia coli , 2017, Journal of Industrial Microbiology & Biotechnology.

[12]  Jian‐He Xu,et al.  Engineering 7β-Hydroxysteroid Dehydrogenase for Enhanced Ursodeoxycholic Acid Production by Multiobjective Directed Evolution. , 2017, Journal of agricultural and food chemistry.

[13]  E. Boles,et al.  Parallelised online biomass monitoring in shake flasks enables efficient strain and carbon source dependent growth characterisation of Saccharomycescerevisiae , 2016, Microbial Cell Factories.

[14]  V. Titorenko,et al.  Lithocholic bile acid accumulated in yeast mitochondria orchestrates a development of an anti-aging cellular pattern by causing age-related changes in cellular proteome , 2015, Cell cycle.

[15]  Jian‐He Xu,et al.  Two-step enzymatic synthesis of ursodeoxycholic acid with a new 7β-hydroxysteroid dehydrogenase from Ruminococcus torques , 2015 .

[16]  T. Eggert,et al.  Enzymatic routes for the synthesis of ursodeoxycholic acid. , 2014, Journal of biotechnology.

[17]  H. Yang,et al.  Hyaluronic Acid Production by Genetic Modified GRAS Strains , 2014 .

[18]  S. Fukiya,et al.  Contribution of the 7β-hydroxysteroid dehydrogenase from Ruminococcus gnavus N53 to ursodeoxycholic acid formation in the human colon[S] , 2013, Journal of Lipid Research.

[19]  Jianzhu Liu,et al.  The effects of taurochenodeoxycholic acid in preventing pulmonary fibrosis in mice. , 2013, Pakistan journal of pharmaceutical sciences.

[20]  D. Weuster‐Botz,et al.  One-step synthesis of 12-ketoursodeoxycholic acid from dehydrocholic acid using a multienzymatic system , 2012, Applied Microbiology and Biotechnology.

[21]  Sergio Riva,et al.  In search of sustainable chemical processes: cloning, recombinant expression, and functional characterization of the 7α- and 7β-hydroxysteroid dehydrogenases from Clostridium absonum , 2011, Applied Microbiology and Biotechnology.

[22]  S. Tsao,et al.  Bear bile: dilemma of traditional medicinal use and animal protection , 2009, Journal of ethnobiology and ethnomedicine.

[23]  Wei Li,et al.  Bile acids metabonomic study on the CCl4- and alpha-naphthylisothiocyanate-induced animal models: quantitative analysis of 22 bile acids by ultraperformance liquid chromatography-mass spectrometry. , 2008, Chemical research in toxicology.

[24]  A. Toledo,et al.  Taurodeoxycholate Stimulates Intestinal Cell Proliferation and Protects Against Apoptotic Cell Death Through Activation of NF-κB , 2004, Digestive Diseases and Sciences.

[25]  A. Görg,et al.  Comparison of the Proteomes of Three Yeast Wild Type Strains: CEN.PK2, FY1679 and W303 , 2001, Comparative and functional genomics.

[26]  T. Iida,et al.  An improved synthesis of taurine- and glycine-conjugated bile acids , 1997, Lipids.

[27]  T. Yoshimoto,et al.  Cloning and sequencing of the 7 alpha-hydroxysteroid dehydrogenase gene from Escherichia coli HB101 and characterization of the expressed enzyme , 1991, Journal of bacteriology.