Synthesis, in Vitro Bio-evaluation, and Molecular Docking Study of Thiosemicarbazone-based Isatin/bis-Schiff base Hybrid Analogues as Effective Cholinesterase Inhibitors
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R. Hussain | H. Ullah | Misbah Ullah Khan | Shoaib Khan | Mehmand Khan | Abdul Sattar | Muhammad Saleem Khan | Yousaf Khan
[1] Y. Zorlu,et al. Synthesis and molecular modeling studies of naphthazarin derivatives as novel selective inhibitors of α-glucosidase and α-amylase , 2023, Journal of Molecular Structure.
[2] R. Hussain,et al. Synthesis, In Vitro α-Glucosidase Inhibitory Activity and Molecular Docking Study of New Benzotriazole-Based Bis-Schiff Base Derivatives , 2022, Pharmaceuticals.
[3] R. Hussain,et al. Synthesis of New Triazole-Based Thiosemicarbazone Derivatives as Anti-Alzheimer’s Disease Candidates: Evidence-Based In Vitro Study , 2022, Molecules.
[4] W. Dong,et al. Novel phenoxo-bridged di- and tri-nuclear Cu(II) salamo-like complexes driven by various counter-anions , 2022, Inorganica Chimica Acta.
[5] R. Hussain,et al. Benzoxazole based thiazole hybrid analogs: Synthesis, in vitro cholinesterase inhibition, and molecular docking studies , 2022, Computational Toxicology.
[6] W. Dong,et al. Solvent-driven self-assembly of two novel di- and tetra-nuclear Cu(II) bis(salamo)-based complexes , 2022, Journal of Molecular Structure.
[7] W. Dong,et al. An investigation of two heterobimetallic [Cu(II)2Ln(III)] (Ln = La and Ce) complexes of a more flexible bis(salamo)‐type ligand , 2022, Journal of Molecular Structure.
[8] R. Hussain,et al. Molecular iodine-promoted oxidative cyclization for the synthesis of 1,3,4-thiadiazole-fused- [1,2,4]-thiadiazole incorporating 1,4-benzodioxine moiety as potent inhibitors of α-amylase and α-glucosidase: In vitro and in silico study , 2022, Frontiers in Chemistry.
[9] M. Awad,et al. Benzimidazole Bearing Thiosemicarbazone Derivatives Act as Potent α-Amylase and α-Glucosidase Inhibitors; Synthesis, Bioactivity Screening and Molecular Docking Study , 2022, Molecules.
[10] R. Hussain,et al. New Triazinoindole Bearing Benzimidazole/Benzoxazole Hybrids Analogs as Potent Inhibitors of Urease: Synthesis, In Vitro Analysis and Molecular Docking Studies , 2022, Molecules.
[11] R. Hussain,et al. Synthesis of Novel Benzimidazole-Based Thiazole Derivatives as Multipotent Inhibitors of α-Amylase and α-Glucosidase: In Vitro Evaluation along with Molecular Docking Study , 2022, Molecules.
[12] R. Hussain,et al. Multipotent Cholinesterase Inhibitors for the Treatment of Alzheimer’s Disease: Synthesis, Biological Analysis and Molecular Docking Study of Benzimidazole-Based Thiazole Derivatives , 2022, Molecules.
[13] R. Hussain,et al. New biologically potent benzimidazole‐based‐triazole derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors along with molecular docking study , 2022, Journal of Heterocyclic Chemistry.
[14] N. El‐Metwaly,et al. Novel organoselenium-based N-mealanilic acid and its zinc (II) chelate: Catalytic, anticancer, antimicrobial, antioxidant, and computational assessments , 2022, Journal of Molecular Liquids.
[15] N. El‐Metwaly,et al. Synthesis and Investigation of Bivalent Thiosemicarbazone Complexes: Conformational Analysis, Methyl Green DNA Binding and In-silico Studies , 2022, Arabian Journal for Science and Engineering.
[16] A. Alrefaei,et al. Green synthesis for new Co(II), Ni(II), Cu(II) and Cd(II) hydrazone-based complexes; characterization, biological activity and electrical conductance of nano-sized copper sulphate , 2021, Journal of Molecular Structure.
[17] Tahani M. Bawazeer,et al. Synthesis and characterization of new thiazole-based Co(II) and Cu(II) complexes; therapeutic function of thiazole towards COVID-19 in comparing to current antivirals in treatment protocol , 2021, Journal of Molecular Structure.
[18] Razieh Sabet,et al. Quantitative Structure Activity Relationship of New Isatin Analogues for Design New Compounds as Anti-breast Cancer , 2019, Journal of Pharmaceutical Research International.
[19] M. Gabr,et al. Design and synthesis of donepezil analogues as dual AChE and BACE-1 inhibitors. , 2018, Bioorganic chemistry.
[20] A. Ivanov,et al. Isatin, an endogenous nonpeptide biofactor: A review of its molecular targets, mechanisms of actions, and their biomedical implications , 2018, BioFactors.
[21] L. Teh,et al. Synthesis of azomethines derived from cinnamaldehyde and vanillin: in vitro aetylcholinesterase inhibitory, antioxidant and insilico molecular docking studies , 2018, Medicinal Chemistry Research.
[22] A. Abdelhamid,et al. Synthesis and characterization of new pyrazole-based thiazoles , 2017 .
[23] U. Rashid,et al. Rational design and synthesis of dihydropyrimidine based dual binding site acetylcholinesterase inhibitors. , 2016, Bioorganic chemistry.
[24] H. Ullah,et al. Synthesis and in vitro acetylcholinesterase and butyrylcholinesterase inhibitory potential of hydrazide based Schiff bases. , 2016, Bioorganic chemistry.
[25] L. Teh,et al. Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies. , 2016, Bioorganic chemistry.
[26] Qurat-Ul-Ain,et al. Synthesis, molecular docking, acetylcholinesterase and butyrylcholinesterase inhibitory potential of thiazole analogs as new inhibitors for Alzheimer disease. , 2015, Bioorganic chemistry.
[27] Mohammad A Kamal,et al. Status of acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease and type 2 diabetes mellitus. , 2014, CNS & neurological disorders drug targets.
[28] Maurizio Recanatini,et al. Multi-target-directed ligands to combat neurodegenerative diseases. , 2008, Journal of medicinal chemistry.
[29] R. Quirion,et al. Alzheimer’s disease and the basal forebrain cholinergic system: relations to β-amyloid peptides, cognition, and treatment strategies , 2002, Progress in Neurobiology.
[30] Marsel Mesulam,et al. Widely Spread Butyrylcholinesterase Can Hydrolyze Acetylcholine in the Normal and Alzheimer Brain , 2002, Neurobiology of Disease.
[31] J. Mintzer,et al. Effects of a flexible galantamine dose in Alzheimer's disease: a randomised, controlled trial , 2001, Journal of neurology, neurosurgery, and psychiatry.
[32] Xiaoxiang Zhu,et al. A New Therapeutic Target in Alzheimer's Disease Treatment: Attention to Butyrylcholinesterase , 2001, Current medical research and opinion.
[33] D. Melzer. New drug treatment for Alzheimer's disease: lessons for healthcare policy , 1998, BMJ.
[34] M. Jann,et al. Preclinical Pharmacology of Metrifonate , 1998, Pharmacotherapy.
[35] K. Davis,et al. The search for disease-modifying treatment for Alzheimer's disease , 1997, Neurology.
[36] F. Vallette,et al. Molecular and cellular biology of cholinesterases , 1993, Progress in Neurobiology.
[37] O. Parsons,et al. Neuropsychology of dementia. , 1986, Neurologic clinics.
[38] A. Comeau,et al. Pseudocholinesterases of mammalian plasma: physicochemical properties and organophosphate inhibition in eleven species. , 1973, Toxicology and applied pharmacology.