Primary Anetoderma in Children: Report of Two Cases and Literature Review

Abstract: Two boys, age 7 and 9 years, with the diagnosis of primary anetoderma are presented, in one patient a growing number of indolent lesions developed for one year on the neck. The other boy complained of Single lesions appearing over four months on the arms, teet, and chest wall. Individual lesions measured up to 1 cm In diameter and showed a palpable herniation phenomenon and wrinkled surface. The lesions did not have an inflammatory onset. Histologically, in both patients the diagnosis of anetoderma was verified by loss of elastic fibers and a lympho‐histiocytic infiltration in the middermis. Administration of oral penicillin for three weeks did not result in marked improvement, and atrophic macules continued to appear in the younger boy. Although no autoimmune logic abnormalities or other associated diseases have arisen in our patients, long‐term follow‐up is mandatory to detect autoimmune disorders that are reported to occur In the course of the disease.