论文信息 - EFFECTS OF LOW-LEVEL IRRADIATION ON FITNESS AND SKELETAL VARIATION IN AN INBRED MOUSE STRAIN.

EFFECTS OF LOW-LEVEL IRRADIATION ON FITNESS AND SKELETAL VARIATION IN AN INBRED MOUSE STRAIN.

the taneous mutations affecting the frequencies of particular variants and becoming incorporated into particular sublines. The rate of subline differentiation is thus a measure of the mutation rate to the genes concerned, which are essentially the same as the “polygenes” of continuous variation. GRUNEBERG therefore suggested that a comparison of the rate of subline differentiation with and without the added factor of irradiation should make it possible to estimate the radiation- induced mutation rate for this type of variation. This is what was attempted in the present experiment.

A. Searle

[1] R. Phillips,et al. THE EFFECT OF DOSE-RATE ON THE YIELD OF TRANSLOCATIONS AND DOMINANT LETHALS FOLLOWING SPERMATOGONIAL IRRADIATION OF MICE , 1964 .

[2] M. Lyon,et al. The overall rates of dominant and recessive lethal and visible mutation induced by spermatogonial X-irradiation of mice , 1964 .

[3] K. Luening. STUDIES OF IRRADIATED MOUSE POPULATIONS. 3. ACCUMULATION OF RECESSIVE LETHALS. , 1964, Mutation research.

[4] R. Edwards,et al. Genetic radiosensitivity of specific post-dictyate stages in mouse oocytes. , 1963 .

[5] B. Wallace. Further Data on the Overdominance of Induced Mutations. , 1963, Genetics.

[6] M. Grewal. The rate of genetic divergence of sublines in the c57bl strain of mice. , 1962 .

[7] M. Lyon,et al. An attempt to estimate the induction by x-rays of recessive lethal and visible mutations in mice. , 1961 .

[8] H. Grüneberg,et al. Genetical differentiation involving morphological characters in an inbred strain of mice. I. A british branch of the C57BL strain , 1957 .