论文信息 - A 32-ch. bidirectional neural/EMG interface with on-chip spike detection for sensorimotor feedback

A 32-ch. bidirectional neural/EMG interface with on-chip spike detection for sensorimotor feedback

This paper presents a novel 32-channel bidirectional neural interface, capable of high voltage stimulation and low-power, low-noise neural recording. Current-controlled biphasic pulses are output with a voltage compliance of 9.25 V, user-configurable amplitude (max. 315 μA) & phase duration (max. 2 ms). The low-voltage recording amplifiers consume 23 μW per channel with programmable gain between 225–4725. Signals are 10-bit sampled at 16 kHz. Data rates are reduced by granular control of active recording channels, spike detection and event-driven communication, and repeatable multi-pulse stimulation configurations.

Timothy G. Constandinou | Ian Williams | Song Luan | Adrien Rapeaux | Yan Liu

[1] Awais M. Kamboh,et al. A CMOS Micro-power and Area Efficient Neural Recording and Stimulation Front-End for Biomedical Applications , 2015, Circuits Syst. Signal Process..

[2] Timothy G. Constandinou,et al. Computationally efficient modeling of proprioceptive signals in the upper limb for prostheses: a simulation study , 2014, Front. Neurosci..

[3] Maurits Ortmanns,et al. A bidirectional neural interface IC with high voltage compliance and spectral separation , 2016, 2016 IEEE International Symposium on Circuits and Systems (ISCAS).

[4] Takashi Tateno,et al. A CMOS IC-based multisite measuring system for stimulation and recording in neural preparations in vitro , 2014, Front. Neuroeng..

[5] Anne Beuter. Parkinson's Disease: Deep Brain Stimulation , 2014, Encyclopedia of Computational Neuroscience.

[6] Hsi-Pin Ma,et al. A Battery-Less, Implantable Neuro-Electronic Interface for Studying the Mechanisms of Deep Brain Stimulation in Rat Models , 2016, IEEE Transactions on Biomedical Circuits and Systems.

[7] I. Soltesz,et al. Future of seizure prediction and intervention: closing the loop. , 2015, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.