Sustainable Electro-Responsive Semi-Interpenetrating Starch/Ionic Liquid Copolymer Networks for the Controlled Sorption/Release of Biomolecules

The main objective of this work was the development and characterization of sustainable electro-responsive ionic liquid-based cationic copolymers. For this purpose degradable semi-interpenetrating polymer networks (s-IPNs) based on starch and on ion-conducting cationic copolymers of 2-hydroxyethyl methacrylate (HEMA) and 1-butyl-3-vinylimidazolium chloride (BVImCl), cross-linked with N,N′-methylenebis(acrylamide) (MBA), were synthesized by following principles of green chemistry. Cross-linked poly(HEMA-co-BVImCl) copolymers were also prepared for comparison. The resulting cationic hydrogels (copolymer and s-IPNs) were characterized in terms of their physicochemical, thermomechanical, morphological, and electrochemical properties, as well as in terms of cell viability and proliferation against fibroblast cells. Furthermore, the electro-assisted sorption/release capacity of the prepared hydrogels toward l-tryptophan (used as a model biomolecule) was also studied at different applied DC voltages (0, 2, 5, an...

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